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Understanding Pathophysiology 7th edition by Huethe
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,Understanding Pathophysiology 7th edition by Huether, McCance Test Bank
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s
ate st Updated Examination Study Guide2022
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Chapter 1. Cellular Biology
MULTIPLECHOICE
1. Astudentisobservingacellunderthemicroscope. It isobservedtohavesupercoiled DN
A with histones. Whichofthefollowingwouldalsobeobservedbythestudent?
a. Asinglecircularchromosome
b. Anucleus
c. Free-floatingnuclearmaterial
d. Nolorganelles
ANS: B
Thelcelldescribedis aeukaryoticcell, so it has histonesandasupercoiled DNA withinitsnucle
us; th us,lthenucleusshouldbeobserved.
Asinglecircularchromosomeischaracteristicofprokaryoticcells, whichdonothavehistones.
Free-
floatinglnuclearmaterialdescribesaprokaryoticcell, whichwouldnotlhaveadistinctnucleus.
Eukaryoticlcellshavelmembraneboundedcellularcomponentscalledorganelles. No organellesdes
cribeslaprokaryoticcell.
2. Anurseisinstructingthelstaffaboutcellularfunctions. Whichcellularfunctionlisthenursedesc
ribingwhen an isolatedlcell absorbsoxygenandusesittoltransformlnutrients
toenergy?
a. Metaboliclabsorption
b. Communication
c. Secretion
d. Respiration
,Understanding Pathophysiology 7th edition by Huether, McCance Test Bank
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ANS: D
Thelabilityofthelcell toabsorboxygenrefersltothecellsfunctionofrespiration.
Thelabilityofthecelltofunctionwithinasocietyofcellsreferstoitsfunctionofcommunication.
Thelabilityof thecell totakein nutrients refersto thecellsfunction ofmetabolica
bsorption.
Theabilityofthelcelltosynthesizenewsubstancesandsecretetheselelsewherereferstothecellsfunction
ofsecretion.
3. Aeukaryoticcellisundergoing DNA replication. In whichregionofthecellwouldmo
stoftheg eneticinformationbecontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS: C
Thelregionofthelcellthatcontainsgeneticmaterial, includingalargeamountofribonucleicacid, m
ostofthe DNA, and DNA-binding proteins, isthenucleolus.
Thelmitochondriaisthesiteofcellularrespiration.
Thelribosomesareinvolvedinmanufacturingofproteinswithinthecell.
Thelnucleuscontainslthelnucleolus, anditisthenucleolusthatcontainsgeneticmaterial.
4. Thelfluidmosaiclmodelforbiologicmembranesdescribesmembranebehavior. Accordingtothis
model, whichofthefollowingfloatlsinglyor as aggregatesinlthefluid lipid bila
yer?
a. Peripheralmembraneproteins
b. Integralmembraneproteins
, Understanding Pathophysiology 7th edition by Huether, McCance Test Bank
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c. Glycoproteins
d. Celladhesionmolecules
ANS: B
Integralmembraneproteins float freelyinthefluidlipid bilayer.
Peripheralmembraneproteinsarenot embeddedinlthelayer, butreside at thesurface. Gl
ycoprotein s act as cell surfacemarkers.
Celladhesionmoleculesareontheoutsideofthemembraneandallowcellstohooktogether.
5. Whichofthefollowing can bindtoplasmamembranereceptors?
a. Oxygen
b. Ribosomes
c. Amphipathiclipids
d. Ligands
ANS: D
Ligandslarelspecificmoleculesthat can bindwithreceptorsonthecellmembrane. Oxygen movesb
ydiffusion; it doesnotbindto receptors.
Ribosomesmakeproteinsandarenotinvolvedinbinding. A mphipathicli
pidsareaportionofthecell membrane.
6. Anurselisreviewingareportfrom apatientwithmetastaticcancer. Whatfindingwouldsupp
ortthediagnosisofmetastaticcancer? Alterationsinextracellularmatrixthat include:
a. Decreasedfibronectin
b. Increasedcollagen
c. Decreasedelastin