Western Governors University D 236
Pathophysiology Exam 1 with question and answer 100%
correct
An ordered photographic display of a set of c
chromosomes from a single cell is a(n):
A) metaphase spread.
B)autosomal spread.
C) karyotype.
D)anaphase spread.
An error in which homologous b
chromosomes fail to separate during
meiosis is termed:
A) aneuploidy.
B)nondisjunction.
C) polyploidy.
D)anaplasia.
,A somatic cell that does not contain a
a multiple of 23 chromosomes is called:
A) an aneuploid cell.
B)a euploid cell.
C) a polyploidy cell.
D)a haploid cell.
A 20-year-old pregnant female gives birth c
to a stillborn child. Autopsy reveals that the
fetus has 92 chromosomes. Which of
the following describes this
condition?
A) Euploidy
B) Triploidy
C) Tetraploidy
D)Aneuploidy
If a person is a chromosomal mosaic, the b
person may:
A) be a carrier of the genetic disease.
B)have a mild form of the genetic disease.
C) have two genetic diseases.
D) be sterile as a result of the
genetic disease.
The most common cause of Down c
syndrome is:
A) paternal nondisjunction.
B)maternal translocations.
C) maternal nondisjunction.
D) paternal translocations.
Risk factors for Down syndrome include: d
A) fetal exposure to mutagens in the uterus.
B)increased paternal age.
C) family history of Down syndrome.
D) pregnancy in women over age 35.
A 13-year-old girl has a karyotype that c
reveals an absent homologous X
chromosome with only a single X
chromosome present. Her condition is
called:
A) Down syndrome.
B)Cri du chat syndrome.
C) Turner syndrome.
D) Edward syndrome
,A child is diagnosed with cystic fibrosis. c
History reveals that the child's parents are
first cousins. Cystic fibrosis was most likely
the result of:
A) X inactivation.
B)genomic imprinting.
C) consanguinity.
D) obligate carriers.
Joey, age 9, is admitted to a pediatric unit d
with Duchenne muscular dystrophy. He
inherited this condition through a:
A) sex-linked dominant trait.
B)sex-influenced trait.
C) sex-limited trait.
D) sex-linked recessive trait.
A 50-year-old male was recently diagnosed d
with Huntington disease. Transmission of this
disease is associated with:
A) penetrance.
B)recurrence risk.
C) expressivity.
D) delayed age of onset.
People who have neurofibromatosis will b
show varying degrees of the disease; this is
because of the genetic principle of:
A) penetrance.
B)expressivity.
C) dominance.
D)recessiveness.
Cystic fibrosis is caused by an _____ gene. d
A) X-linked dominant
B)X-linked recessive
C) autosomal dominant
D)autosomal recessive
To express a polygenic trait: b
A) genes must interact with the environment.
B)several genes must act together.
C) multiple mutations must occur in
the same family.
D) in situ cloning must occur.
The gradual increase in height among the b
human population over the past 100 years is
an example of:
A) polygenic trait.
B)multifactorial trait.
C) crossing over.
D)recombination.
, A couple has three offspring: one child with
a an autosomal dominant disease trait and
two
who are normal. The father is affected
by the autosomal dominant disease, but
the mother does not have the disease
gene.
What is the recurrence risk of this
autosomal dominant disease for their
next child?
A) 50%
B)33%
C) 25%
D) Impossible to determine
A 12-year-old male is diagnosed with d
Klinefelter syndrome. His karyotype would
reveal which of the following?
A) XY
B)XX
C) XYY
D)XXY
A 5-year-old male presents with mental d
retardation and is diagnosed with Fragile X
syndrome. Which of the following is most
likely to cause this syndrome?
A)Translocation
B)Inversion
C) Nondisjunction
D) Duplication at fragile sites
The outward manifestation of a disease, c
often influenced by both genes and the
environment, is called the disease:
A) genotype.
B)allele.
C) phenotype.
D)dominance.
Which of the following genetic diseases d
manifests with progressive dementia in
middle to later adulthood?
A) Duchenne muscular dystrophy
B)Cystic fibrosis
C) Achondroplasia
D) Huntington disease
Which of the following types of genetic d
disorders is the most common cause of
miscarriage?
A) Autosomal dominant
B)Autosomal recessive
C) X-linked recessive
D)Chromosomal
Pathophysiology Exam 1 with question and answer 100%
correct
An ordered photographic display of a set of c
chromosomes from a single cell is a(n):
A) metaphase spread.
B)autosomal spread.
C) karyotype.
D)anaphase spread.
An error in which homologous b
chromosomes fail to separate during
meiosis is termed:
A) aneuploidy.
B)nondisjunction.
C) polyploidy.
D)anaplasia.
,A somatic cell that does not contain a
a multiple of 23 chromosomes is called:
A) an aneuploid cell.
B)a euploid cell.
C) a polyploidy cell.
D)a haploid cell.
A 20-year-old pregnant female gives birth c
to a stillborn child. Autopsy reveals that the
fetus has 92 chromosomes. Which of
the following describes this
condition?
A) Euploidy
B) Triploidy
C) Tetraploidy
D)Aneuploidy
If a person is a chromosomal mosaic, the b
person may:
A) be a carrier of the genetic disease.
B)have a mild form of the genetic disease.
C) have two genetic diseases.
D) be sterile as a result of the
genetic disease.
The most common cause of Down c
syndrome is:
A) paternal nondisjunction.
B)maternal translocations.
C) maternal nondisjunction.
D) paternal translocations.
Risk factors for Down syndrome include: d
A) fetal exposure to mutagens in the uterus.
B)increased paternal age.
C) family history of Down syndrome.
D) pregnancy in women over age 35.
A 13-year-old girl has a karyotype that c
reveals an absent homologous X
chromosome with only a single X
chromosome present. Her condition is
called:
A) Down syndrome.
B)Cri du chat syndrome.
C) Turner syndrome.
D) Edward syndrome
,A child is diagnosed with cystic fibrosis. c
History reveals that the child's parents are
first cousins. Cystic fibrosis was most likely
the result of:
A) X inactivation.
B)genomic imprinting.
C) consanguinity.
D) obligate carriers.
Joey, age 9, is admitted to a pediatric unit d
with Duchenne muscular dystrophy. He
inherited this condition through a:
A) sex-linked dominant trait.
B)sex-influenced trait.
C) sex-limited trait.
D) sex-linked recessive trait.
A 50-year-old male was recently diagnosed d
with Huntington disease. Transmission of this
disease is associated with:
A) penetrance.
B)recurrence risk.
C) expressivity.
D) delayed age of onset.
People who have neurofibromatosis will b
show varying degrees of the disease; this is
because of the genetic principle of:
A) penetrance.
B)expressivity.
C) dominance.
D)recessiveness.
Cystic fibrosis is caused by an _____ gene. d
A) X-linked dominant
B)X-linked recessive
C) autosomal dominant
D)autosomal recessive
To express a polygenic trait: b
A) genes must interact with the environment.
B)several genes must act together.
C) multiple mutations must occur in
the same family.
D) in situ cloning must occur.
The gradual increase in height among the b
human population over the past 100 years is
an example of:
A) polygenic trait.
B)multifactorial trait.
C) crossing over.
D)recombination.
, A couple has three offspring: one child with
a an autosomal dominant disease trait and
two
who are normal. The father is affected
by the autosomal dominant disease, but
the mother does not have the disease
gene.
What is the recurrence risk of this
autosomal dominant disease for their
next child?
A) 50%
B)33%
C) 25%
D) Impossible to determine
A 12-year-old male is diagnosed with d
Klinefelter syndrome. His karyotype would
reveal which of the following?
A) XY
B)XX
C) XYY
D)XXY
A 5-year-old male presents with mental d
retardation and is diagnosed with Fragile X
syndrome. Which of the following is most
likely to cause this syndrome?
A)Translocation
B)Inversion
C) Nondisjunction
D) Duplication at fragile sites
The outward manifestation of a disease, c
often influenced by both genes and the
environment, is called the disease:
A) genotype.
B)allele.
C) phenotype.
D)dominance.
Which of the following genetic diseases d
manifests with progressive dementia in
middle to later adulthood?
A) Duchenne muscular dystrophy
B)Cystic fibrosis
C) Achondroplasia
D) Huntington disease
Which of the following types of genetic d
disorders is the most common cause of
miscarriage?
A) Autosomal dominant
B)Autosomal recessive
C) X-linked recessive
D)Chromosomal
