NUR 600 Exam 1 Questions and Correct
Answers Updated
Question 1
All drugs continue to act in the body until they are changed or excreted. The ability of
the body to excrete drugs via the renal system would be increased by:
A. Reduced circulation and perfusion of the kidney
B. Chronic renal disease
C. Competition for a transport site by another drug
D. Unbinding a nonvolatile drug from plasma proteins
Correct Answer
D. Unbinding a nonvolatile drug from plasma proteins
Question 2
client has been receiving a cephalosporin for 20 days to treat a severe bacterial
infection. The client complains of mouth pain, and the nurse assesses white patches in
the client's mouth. What is the highest priority action on the part of the nurse?
a. Provide mouth care with glycerin swabs.
b. Encourage the client to drink more fluids.
c. Notify the physician and describe symptoms.
d. Administer analgesia for the mouth pain.
Correct Answer
c. Notify the physician and describe symptoms.
Question 3
Infants and young children are at higher risk of ADRs due to:
A. Immature renal function in school-age children
B. Lack of safety and efficacy studies in the pediatric population
C. Children's skin being thicker than adults, requiring higher dosages of topical
medication
D. Infant boys having a higher proportion of muscle mass, leading to a higher volume
of distribution
Correct Answer
B. Lack of safety and efficacy studies in the pediatric population
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,Question 4
Drugs administered via intravenous (IV) route:
A. Need to be lipid soluble in order to be easily absorbed
B. Begin distribution into the body immediately
C. Are easily absorbed if they are nonionized
D. May use pinocytosis to be absorbed
Correct Answer
B. Begin distribution into the body immediately
Question 5
Steps to avoid polypharmacy include:
A. Prescribing two or fewer drugs from each drug class
B. Reviewing a complete drug history every 12 to 18 months
C. Encouraging the elderly patient to coordinate their care with all of their providers
D. Evaluating for duplications in drug therapy and discontinuing any duplications
Correct Answer
D. Evaluating for duplications in drug therapy and discontinuing any duplications
Question 6
Criteria for choosing an effective drug for a disorder include:
A. Asking the patient what drug they think would work best for them
B. Consulting nationally recognized guidelines for disease management
C. Prescribing medications that are available as samples before writing a prescription
D. Following U.S. Drug Enforcement Administration (DEA) guidelines for prescribing
Correct Answer
B. Consulting nationally recognized guidelines for disease management
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,Question 7
Cardiac defects are a known Type D adverse drug reaction to lithium. Lithium causes a
Type D adverse drug reaction because it is:
A. An immunosuppressant
B. A carcinogen
C. A teratogen
D. An antiseizure medication
Correct Answer
C. A teratogen
Question 8
A client is admitted to the labor and delivery unit and is being treated with terbutaline
(Brethine). The nurse plans the client's care with the knowledge that this medication is
used to:
a. induce labor.
b. decrease uterine contractions.
c. stimulate fetal heart rate.
d. enhance placental blood flow.
Correct Answer
b. decrease uterine contractions.
Question 9
Sadie is a 90-year-old patient who requires a new prescription. What changes in drug
distribution with aging would influence prescribing for Sadie?
A. Increased volume of distribution
B. Decreased lipid solubility
C. Decreased plasma proteins
D. Increased muscle to fat ratio
Correct Answer
C. Decreased plasma proteins
Page 3 of 55
, Question 10
Sarah developed a rash after using a topical medication. This is a Type __ allergic drug
reaction.
A. I
B. II
C. III
D. IV
Correct Answer
D. IV
Question 11
Clopidogrel treatment failure may occur when it is co-administered with omeprazole,
known as a Type __ adverse drug reaction.
A. A
B. C
C. E
D. F
Correct Answer
D. F
Question 12
Which of the following statements about bioavailability is true?
A. Bioavailability issues are especially important for drugs with narrow therapeutic
ranges or sustained release mechanisms.
B. All brands of a drug have the same bioavailability.
C. Drugs that are administered more than once a day have greater bioavailability than
drugs given once daily.
D. Combining an active drug with an inert substance does not affect
Correct Answer
A. Bioavailability issues are especially important for drugs with narrow therapeutic
ranges or sustained release mechanisms.
Page 4 of 55
Answers Updated
Question 1
All drugs continue to act in the body until they are changed or excreted. The ability of
the body to excrete drugs via the renal system would be increased by:
A. Reduced circulation and perfusion of the kidney
B. Chronic renal disease
C. Competition for a transport site by another drug
D. Unbinding a nonvolatile drug from plasma proteins
Correct Answer
D. Unbinding a nonvolatile drug from plasma proteins
Question 2
client has been receiving a cephalosporin for 20 days to treat a severe bacterial
infection. The client complains of mouth pain, and the nurse assesses white patches in
the client's mouth. What is the highest priority action on the part of the nurse?
a. Provide mouth care with glycerin swabs.
b. Encourage the client to drink more fluids.
c. Notify the physician and describe symptoms.
d. Administer analgesia for the mouth pain.
Correct Answer
c. Notify the physician and describe symptoms.
Question 3
Infants and young children are at higher risk of ADRs due to:
A. Immature renal function in school-age children
B. Lack of safety and efficacy studies in the pediatric population
C. Children's skin being thicker than adults, requiring higher dosages of topical
medication
D. Infant boys having a higher proportion of muscle mass, leading to a higher volume
of distribution
Correct Answer
B. Lack of safety and efficacy studies in the pediatric population
Page 1 of 55
,Question 4
Drugs administered via intravenous (IV) route:
A. Need to be lipid soluble in order to be easily absorbed
B. Begin distribution into the body immediately
C. Are easily absorbed if they are nonionized
D. May use pinocytosis to be absorbed
Correct Answer
B. Begin distribution into the body immediately
Question 5
Steps to avoid polypharmacy include:
A. Prescribing two or fewer drugs from each drug class
B. Reviewing a complete drug history every 12 to 18 months
C. Encouraging the elderly patient to coordinate their care with all of their providers
D. Evaluating for duplications in drug therapy and discontinuing any duplications
Correct Answer
D. Evaluating for duplications in drug therapy and discontinuing any duplications
Question 6
Criteria for choosing an effective drug for a disorder include:
A. Asking the patient what drug they think would work best for them
B. Consulting nationally recognized guidelines for disease management
C. Prescribing medications that are available as samples before writing a prescription
D. Following U.S. Drug Enforcement Administration (DEA) guidelines for prescribing
Correct Answer
B. Consulting nationally recognized guidelines for disease management
Page 2 of 55
,Question 7
Cardiac defects are a known Type D adverse drug reaction to lithium. Lithium causes a
Type D adverse drug reaction because it is:
A. An immunosuppressant
B. A carcinogen
C. A teratogen
D. An antiseizure medication
Correct Answer
C. A teratogen
Question 8
A client is admitted to the labor and delivery unit and is being treated with terbutaline
(Brethine). The nurse plans the client's care with the knowledge that this medication is
used to:
a. induce labor.
b. decrease uterine contractions.
c. stimulate fetal heart rate.
d. enhance placental blood flow.
Correct Answer
b. decrease uterine contractions.
Question 9
Sadie is a 90-year-old patient who requires a new prescription. What changes in drug
distribution with aging would influence prescribing for Sadie?
A. Increased volume of distribution
B. Decreased lipid solubility
C. Decreased plasma proteins
D. Increased muscle to fat ratio
Correct Answer
C. Decreased plasma proteins
Page 3 of 55
, Question 10
Sarah developed a rash after using a topical medication. This is a Type __ allergic drug
reaction.
A. I
B. II
C. III
D. IV
Correct Answer
D. IV
Question 11
Clopidogrel treatment failure may occur when it is co-administered with omeprazole,
known as a Type __ adverse drug reaction.
A. A
B. C
C. E
D. F
Correct Answer
D. F
Question 12
Which of the following statements about bioavailability is true?
A. Bioavailability issues are especially important for drugs with narrow therapeutic
ranges or sustained release mechanisms.
B. All brands of a drug have the same bioavailability.
C. Drugs that are administered more than once a day have greater bioavailability than
drugs given once daily.
D. Combining an active drug with an inert substance does not affect
Correct Answer
A. Bioavailability issues are especially important for drugs with narrow therapeutic
ranges or sustained release mechanisms.
Page 4 of 55
