Monday 11 May 2026 – Morning
AS Level Biology B (Advancing Biology)
H022/01 Foundations of biology
Time allowed: 1 hour 30 minutes
You can use:
* 2 6 4 5 8 4 1 1 2 3 *
• a scientific or graphical calculator
• a ruler (cm/mm)
* H 0 2 2 0 1 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© Cambridge OCR 2026 [601/4721/0] Cambridge OCR is an exempt Charity
DC (EV/TC) 363158/5 Turn over
, 2
Section A
You should spend a maximum of 25 minutes on this section.
Write your answer for each question in the box provided.
1 Which of the molecules is not a component commonly found in plasma membranes?
A Cholesterol
B Glycolipid
C Glycoprotein
D Triglyceride
Your answer
[1]
2 Which description of the fluid mosaic model for plasma membranes is correct?
A All phospholipids in the bilayer have tails composed of the same two fatty acids.
B Phospholipids cannot move laterally within each monolayer.
C Proteins in the phospholipid bilayer can be different shapes and sizes.
D Proteins in each monolayer are all the same shape and size.
Your answer
[1]
© Cambridge OCR 2026
, 3
3 Part of a DNA codon chart is shown below.
Second base
Third base
T C A G
First base phenylalanine serine tyrosine cysteine T
T phenylalanine serine tyrosine cysteine C
leucine serine STOP STOP A
leucine serine STOP tryptophan G
Which of the rows, A to D, below shows the correct mRNA codon and tRNA anticodon for the
amino acid, tryptophan?
mRNA codon tRNA anticodon
A ACC TGG
B ACC UGG
C TGG UCC
D UCC AGG
Your answer
[1]
4 At different stages of the cardiac cycle, atrioventricular (AV) and semilunar (SL) valves in the
heart are open or closed.
Which option correctly describes the state of heart valves during diastole?
A AV valves open and SL valves close.
B AV valves close and SL valves open.
C Both AV and SL valves remain open.
D Both AV and SL valves remain closed.
Your answer
[1]
© Cambridge OCR 2026 Turn over
AS Level Biology B (Advancing Biology)
H022/01 Foundations of biology
Time allowed: 1 hour 30 minutes
You can use:
* 2 6 4 5 8 4 1 1 2 3 *
• a scientific or graphical calculator
• a ruler (cm/mm)
* H 0 2 2 0 1 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© Cambridge OCR 2026 [601/4721/0] Cambridge OCR is an exempt Charity
DC (EV/TC) 363158/5 Turn over
, 2
Section A
You should spend a maximum of 25 minutes on this section.
Write your answer for each question in the box provided.
1 Which of the molecules is not a component commonly found in plasma membranes?
A Cholesterol
B Glycolipid
C Glycoprotein
D Triglyceride
Your answer
[1]
2 Which description of the fluid mosaic model for plasma membranes is correct?
A All phospholipids in the bilayer have tails composed of the same two fatty acids.
B Phospholipids cannot move laterally within each monolayer.
C Proteins in the phospholipid bilayer can be different shapes and sizes.
D Proteins in each monolayer are all the same shape and size.
Your answer
[1]
© Cambridge OCR 2026
, 3
3 Part of a DNA codon chart is shown below.
Second base
Third base
T C A G
First base phenylalanine serine tyrosine cysteine T
T phenylalanine serine tyrosine cysteine C
leucine serine STOP STOP A
leucine serine STOP tryptophan G
Which of the rows, A to D, below shows the correct mRNA codon and tRNA anticodon for the
amino acid, tryptophan?
mRNA codon tRNA anticodon
A ACC TGG
B ACC UGG
C TGG UCC
D UCC AGG
Your answer
[1]
4 At different stages of the cardiac cycle, atrioventricular (AV) and semilunar (SL) valves in the
heart are open or closed.
Which option correctly describes the state of heart valves during diastole?
A AV valves open and SL valves close.
B AV valves close and SL valves open.
C Both AV and SL valves remain open.
D Both AV and SL valves remain closed.
Your answer
[1]
© Cambridge OCR 2026 Turn over
