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A4M Board Review Exam | Questions & Verified Answers

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Prepare for the A4M Board Review Exam with verified questions on anti-aging, functional medicine, hormone optimization, and longevity science for .

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A4M review LATEST UPDATES!!! 2026-
2027 | CORRECT SOLUTIONS WITH QUIZ &
ANSWERS | VERIFIED | HIGHLY GRADED
A+

Cerebellum Lobe - CORRECT ANSWERS--Cooridination

Brain Stem - CORRECT ANSWERS--Breathing, speech
-swallowing
-movement
-balance and sleep apnea

Temporal Lobe - CORRECT ANSWERS--theta 4-8
-4-8
-GABBA
-Wernicke's aphasia
-Understand language
-Libido
-Short term memory

Occipital lobe - CORRECT ANSWERS--Delta
-1-4
-Seritonin
-Visual field defects
-Colors
-Hallucinations

Parietal Lobe - CORRECT ANSWERS--alpha waves
-8-12
-Agraphia
-difficulty distinguishing left from right
-calculations
-reading
-apraxia

Front Lobe - CORRECT ANSWERS--Beta
-12-16
-Broca's Aphasia, inability to express language

,-Mood changes

Cortical Dementia - CORRECT ANSWERS--affects cognition, language, memory
-Alzheimer's, CJD,
-Degenerative, Atherosclerotic/infarct, and CJD here

Frontotemporal Demential - CORRECT ANSWERS--personality changes
-compulsive disorders
-visualspatial abilities unchanged picks disease

Dementia with Lewy Bodies - CORRECT ANSWERS--rigidity
-Hallucinations
-Doesn't respond to dopamine , this is a degenerative dementia
-fluctuating cognitive impairment

Subcortical Dementia - CORRECT ANSWERS--slowing of psychomotor abilities and
reduced attention
- Parkinson's and
-vascular dementia, multi-infarct

Sirtuin 1 - CORRECT ANSWERS--Regulates gene expression of various metabolic
pathways
-MEDIATES THE BENEFICIAL EFFECTS OF CALORIC RESTRTRICTION
-Regulates glucose metabolism
-Increase in OsteoBLASTS, decrease in Adipocyes

Dietary Resveratrol - CORRECT ANSWERS--Mimics caloric restriction in MICE
-Inhibits gene expression associated with cardiac skeletal muscle aging in mice
-Modulates insulin mediated glucose uptake in muscle
-Makes yeast live 70% longer
-Acts a a fungicide in plants
-does Not alter SIRT1 levels

B Cells in Age-related Immune System Decline - CORRECT ANSWERS--Antigen
presenting cells and may help T cell development
-Increased in the offspring of healthy centenarians but total number do NOT typically
decline with age

High Exposure to Infections and Innate Immune System - CORRECT ANSWERS--
affects type 1 and type 2 T HELPER cell cytokine response
-Affects Toll-like receptor (TLR) mediated innate immune responses, early antigen
presenting cells
-Deleterious affect on the INNATE immune system

Oteoporosis - CORRECT ANSWERS-- INFLAMMATION is linked with ineffective bone
remodeling and increased bone resorption

, -E2, Estradiol deficiency
-Aging and estrogen deficiency two biggest risks
-Osteoporosis and immunosenescence accompanied by TNF, IL-1 and RANK-1
increased osteoCLASTIC inflammation

Periodontal Disease - CORRECT ANSWERS--Gram negative ANAEROBIC correlated
with atherosclerosis
-Worsens diabetes
-Slows wound healing
-loss of ALVEOLAR bone and teeth b/c of osteoCLASTIC activity

DHEA Oral Administration Elderly Men - CORRECT ANSWERS--Increases number of
MONOcytes between 2-20 weeks post treatment, 2-20 weeks
-10-20% increase in serum IGF-1 as early as 4 weeks
-Supplementation decreases lipofuscin accumulation in the brain in animals

Transdermal Estrogen - CORRECT ANSWERS--Reduces CAD
-Vasodilator
-Improves cholesterol, in humans and only transdermal

Progesterone - CORRECT ANSWERS--IV admin. blunts inflammatory cytokinde in TBI

Testosterone Replacement - CORRECT ANSWERS--Has shown to improve mood and
muscle mass
-No effect on COGNITIVE ability

Women Menopause Changes - CORRECT ANSWERS--Testosterone, DHT, 3
androstenedione, and estrogen
-Irritability and Depression

Low DHEA, and estrogen/progesterone imbalance - CORRECT ANSWERS--Increase
body fat
-Decreases lean body mass

What improves low bone marrow density - CORRECT ANSWERS--Testosterone
-Growth Hormone

Testosterone Replacement Therapy - CORRECT ANSWERS--Improves Depressive
Symptoms
-Promotes Lean muscle mass
-Improves Cholesterol profile
-improves visual and working memory in men
• Has shown to improve mood and muscle mass in andropausal men but did not affect
cognitive ability

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