NSG 533 OPIOID QUIZ LATEST
QUESTIONS AND
ANSWERS 2026 - 2027
Endogenous opioid peptides
Small molecules that are naturally produced in the CNS and in various
glands throughout the body, such as the pituitary and adrenal glands.
Consists of endorphins, enkephalins, dynorphins, and nociceptins.
Mechanism of action for opioids
Stimulating opioid u-receptors in the CNS. Pure agonists (morphine)
bind to u-receptors to produce analgesia that increases with dose without
a ceiling effect. Partial agonists at the u-receptor (Buprenorphine,
tramadol) cause less conformational change and receptor activation than
full agonists.
Indications for initiating opioid therapy
Used when benefits outweigh risks associated with opioids such as
abuse. Used for acute pain (including post-surgical) from under a month,
and chronic pain.
Tolerance
the diminishing effect with regular use of the same dose of a drug,
requiring the user to take larger and larger doses before experiencing the
drug's effect
Dependence
the condition that results when the brain develops a chemical need for a
drug and cannot function normally without it
END OF
PAGE 1
, NSG 533 OPIOID QUIZ LATEST
QUESTIONS AND
ANSWERS 2026 - 2027
Addiction
A physiological or psychological dependence on a drug
Neuralgia
nerve pain
Analgesia
Pain relief; inability to feel pain
Allodynia
Pain due to a stimulus that does not normally provoke pain
When to initiate long-acting opioids
If the short-acting opioids are not working as well in chronic pain or
end-of-life pain, or the patient feels as though their regular dose is not as
effective.
Abuse deterrent opioids
Designed to prevent these altered routes of administration, while
retaining efficacy with oral administration for legitimate pain relief.
Hydrocodone, oxycontin
Breakthrough pain management
Adjuvant medications, immediate-release opioids if necessary
How should a proper dose of opioid be determined
END OF
PAGE 2
QUESTIONS AND
ANSWERS 2026 - 2027
Endogenous opioid peptides
Small molecules that are naturally produced in the CNS and in various
glands throughout the body, such as the pituitary and adrenal glands.
Consists of endorphins, enkephalins, dynorphins, and nociceptins.
Mechanism of action for opioids
Stimulating opioid u-receptors in the CNS. Pure agonists (morphine)
bind to u-receptors to produce analgesia that increases with dose without
a ceiling effect. Partial agonists at the u-receptor (Buprenorphine,
tramadol) cause less conformational change and receptor activation than
full agonists.
Indications for initiating opioid therapy
Used when benefits outweigh risks associated with opioids such as
abuse. Used for acute pain (including post-surgical) from under a month,
and chronic pain.
Tolerance
the diminishing effect with regular use of the same dose of a drug,
requiring the user to take larger and larger doses before experiencing the
drug's effect
Dependence
the condition that results when the brain develops a chemical need for a
drug and cannot function normally without it
END OF
PAGE 1
, NSG 533 OPIOID QUIZ LATEST
QUESTIONS AND
ANSWERS 2026 - 2027
Addiction
A physiological or psychological dependence on a drug
Neuralgia
nerve pain
Analgesia
Pain relief; inability to feel pain
Allodynia
Pain due to a stimulus that does not normally provoke pain
When to initiate long-acting opioids
If the short-acting opioids are not working as well in chronic pain or
end-of-life pain, or the patient feels as though their regular dose is not as
effective.
Abuse deterrent opioids
Designed to prevent these altered routes of administration, while
retaining efficacy with oral administration for legitimate pain relief.
Hydrocodone, oxycontin
Breakthrough pain management
Adjuvant medications, immediate-release opioids if necessary
How should a proper dose of opioid be determined
END OF
PAGE 2
