Page 1 of 98
HESI A2 V2 COMPLETE ENTRANCE EXAM 2026 SOLVED QUESTIONS & ANSWERS
VERIFIED 100 %
HESI A2 V2 Complete Entrance Exam –Questions with Detailed Rationales
SECTION 1: READING COMPREHENSION (Q1–Q40)
Q1. A passage describes how regular exercise strengthens the heart, improves
circulation, releases endorphins, and reduces stress. What is the main idea?
A. Exercise reduces stress only
B. Exercise improves cardiovascular health and mood
C. Endorphins are the primary benefit of exercise
D. Blood circulation is the only benefit of exercise
Correct Answer: B
Rationale: The passage presents multiple benefits; the main idea must synthesize all of
them, not focus on one detail.
Q2. A passage explains that proper hand hygiene prevents infection transmission,
yet compliance among healthcare workers remains low. What is the main idea?
A. Healthcare workers should wear gloves at all times
B. Alcohol-based rubs are superior to soap and water
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C. Hand hygiene is effective but underutilized
D. The CDC issued new guidelines in 2026
Correct Answer: C
Rationale: The passage emphasizes both the effectiveness of hand hygiene and the
problem of low compliance, making C the central claim.
Q3. A passage describes how the digestive system breaks down food through
mechanical and chemical processes, absorbs nutrients, and eliminates waste.
What is the main idea?
A. The stomach produces hydrochloric acid
B. Villi increase surface area for absorption
C. The digestive system converts food into energy and nutrients
D. The liver produces bile
Correct Answer: C
Rationale: Options A, B, and D are supporting details; the overarching concept is the
digestive system's function.
Q4. A passage discusses how honeybee colonies exposed to sub-lethal pesticide
levels show impaired navigation and reduced foraging. What is the primary
conclusion?
A. Pesticides are lethal to all bees
B. Even low-level pesticide exposure disrupts bee behavior
C. Pesticides have no measurable effect on bees
D. Bees naturally avoid treated areas
Correct Answer: B
Rationale: The passage specifies "sub-lethal" exposure causing behavioral changes,
supporting B; A contradicts the passage.
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Q5. A passage explains that hypertension is called the "silent killer" because it has
no symptoms, and screening is essential for early detection. Why is it called the
silent killer?
A. It causes sudden death
B. It has no symptoms
C. It affects millions
D. It is not detectable
Correct Answer: B
Rationale: The passage explicitly states the nickname derives from the absence of
symptoms.
Q6. A patient presents to the emergency department complaining of sudden onset
chest pain radiating to the left arm accompanied by shortness of breath. What is
the most likely diagnosis the nurse should suspect?
A. Anxiety attack
B. Gastroesophageal reflux disease
C. Acute myocardial infarction
D. Muscle strain
Correct Answer: C
Rationale: The classic presentation of acute myocardial infarction includes sudden
onset substernal chest pain that radiates to the left arm or jaw, accompanied by
dyspnea, diaphoresis, and anxiety.
Q7. Read the following passage: "The human body maintains homeostasis through
various regulatory mechanisms. The hypothalamus acts as the body's thermostat,
detecting temperature changes and initiating responses to maintain a stable
internal environment." What is the primary purpose of the hypothalamus according
to the passage?
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A. To regulate hormone production only
B. To maintain body temperature homeostasis through detection and response
C. To control voluntary muscle movement
D. To process sensory information from the skin
Correct Answer: B
Rationale: The passage explicitly states that the hypothalamus "acts as the body's
thermostat, detecting temperature changes and initiating responses to maintain a
stable internal environment."
Q8. Which of the following best describes the main idea of an informational text
about vaccines?
A. Vaccines are harmful and should be avoided at all costs
B. Vaccines work by introducing weakened or inactive pathogens to stimulate immune
response without causing disease
C. Vaccines are only effective for children under the age of five
D. Vaccine development takes only a few weeks
Correct Answer: B
Rationale: This answer accurately describes the mechanism and purpose of vaccines.
Vaccines typically contain weakened or inactivated versions of pathogens that trigger
an immune response, allowing the body to develop immunity without causing the actual
disease.
Q9. What is the main idea of a passage about the water cycle?
A. Oceans are the largest source of water
B. The water cycle describes the continuous movement of water
C. Precipitation only occurs as rain
D. Water never changes state
HESI A2 V2 COMPLETE ENTRANCE EXAM 2026 SOLVED QUESTIONS & ANSWERS
VERIFIED 100 %
HESI A2 V2 Complete Entrance Exam –Questions with Detailed Rationales
SECTION 1: READING COMPREHENSION (Q1–Q40)
Q1. A passage describes how regular exercise strengthens the heart, improves
circulation, releases endorphins, and reduces stress. What is the main idea?
A. Exercise reduces stress only
B. Exercise improves cardiovascular health and mood
C. Endorphins are the primary benefit of exercise
D. Blood circulation is the only benefit of exercise
Correct Answer: B
Rationale: The passage presents multiple benefits; the main idea must synthesize all of
them, not focus on one detail.
Q2. A passage explains that proper hand hygiene prevents infection transmission,
yet compliance among healthcare workers remains low. What is the main idea?
A. Healthcare workers should wear gloves at all times
B. Alcohol-based rubs are superior to soap and water
, Page 2 of 98
C. Hand hygiene is effective but underutilized
D. The CDC issued new guidelines in 2026
Correct Answer: C
Rationale: The passage emphasizes both the effectiveness of hand hygiene and the
problem of low compliance, making C the central claim.
Q3. A passage describes how the digestive system breaks down food through
mechanical and chemical processes, absorbs nutrients, and eliminates waste.
What is the main idea?
A. The stomach produces hydrochloric acid
B. Villi increase surface area for absorption
C. The digestive system converts food into energy and nutrients
D. The liver produces bile
Correct Answer: C
Rationale: Options A, B, and D are supporting details; the overarching concept is the
digestive system's function.
Q4. A passage discusses how honeybee colonies exposed to sub-lethal pesticide
levels show impaired navigation and reduced foraging. What is the primary
conclusion?
A. Pesticides are lethal to all bees
B. Even low-level pesticide exposure disrupts bee behavior
C. Pesticides have no measurable effect on bees
D. Bees naturally avoid treated areas
Correct Answer: B
Rationale: The passage specifies "sub-lethal" exposure causing behavioral changes,
supporting B; A contradicts the passage.
, Page 3 of 98
Q5. A passage explains that hypertension is called the "silent killer" because it has
no symptoms, and screening is essential for early detection. Why is it called the
silent killer?
A. It causes sudden death
B. It has no symptoms
C. It affects millions
D. It is not detectable
Correct Answer: B
Rationale: The passage explicitly states the nickname derives from the absence of
symptoms.
Q6. A patient presents to the emergency department complaining of sudden onset
chest pain radiating to the left arm accompanied by shortness of breath. What is
the most likely diagnosis the nurse should suspect?
A. Anxiety attack
B. Gastroesophageal reflux disease
C. Acute myocardial infarction
D. Muscle strain
Correct Answer: C
Rationale: The classic presentation of acute myocardial infarction includes sudden
onset substernal chest pain that radiates to the left arm or jaw, accompanied by
dyspnea, diaphoresis, and anxiety.
Q7. Read the following passage: "The human body maintains homeostasis through
various regulatory mechanisms. The hypothalamus acts as the body's thermostat,
detecting temperature changes and initiating responses to maintain a stable
internal environment." What is the primary purpose of the hypothalamus according
to the passage?
, Page 4 of 98
A. To regulate hormone production only
B. To maintain body temperature homeostasis through detection and response
C. To control voluntary muscle movement
D. To process sensory information from the skin
Correct Answer: B
Rationale: The passage explicitly states that the hypothalamus "acts as the body's
thermostat, detecting temperature changes and initiating responses to maintain a
stable internal environment."
Q8. Which of the following best describes the main idea of an informational text
about vaccines?
A. Vaccines are harmful and should be avoided at all costs
B. Vaccines work by introducing weakened or inactive pathogens to stimulate immune
response without causing disease
C. Vaccines are only effective for children under the age of five
D. Vaccine development takes only a few weeks
Correct Answer: B
Rationale: This answer accurately describes the mechanism and purpose of vaccines.
Vaccines typically contain weakened or inactivated versions of pathogens that trigger
an immune response, allowing the body to develop immunity without causing the actual
disease.
Q9. What is the main idea of a passage about the water cycle?
A. Oceans are the largest source of water
B. The water cycle describes the continuous movement of water
C. Precipitation only occurs as rain
D. Water never changes state
