,NUR 600 Module 7 Advanced Pharmacology 2026/2027 Questions
And Answers SNHU
Q1. Which medication class generally provides relatively rapid
improvement in lower urinary tract symptoms caused by benign
prostatic hyperplasia?
A) 5-alpha-reductase inhibitors
B) Alpha-1 adrenergic antagonists
C) PDE5 inhibitors used only as needed
D) Antimuscarinic agents alone
Correct Answer: B) Alpha-1 adrenergic antagonists
Rationale: Alpha-1 blockers relax smooth muscle in the prostate and
bladder neck and can improve urinary flow and symptoms relatively quickly.
Q2. Which adverse effect is particularly important when initiating an
alpha-1 blocker for BPH?
A) Hyperkalemia
B) Gingival hyperplasia
C) Severe hypoglycemia
D) Orthostatic hypotension and dizziness
Correct Answer: D) Orthostatic hypotension and dizziness
Rationale: Alpha-1 blockade decreases vascular tone and may cause
postural hypotension, particularly after initial doses or dose escalation.
Q3. Finasteride improves BPH primarily through which mechanism?
A) Inhibition of conversion of testosterone to dihydrotestosterone
B) Direct stimulation of bladder contraction
C) Muscarinic receptor blockade
D) Increased testosterone synthesis
Correct Answer: A) Inhibition of conversion of testosterone to
dihydrotestosterone
Rationale: 5-alpha-reductase inhibition lowers prostatic dihydrotestosterone
concentrations and gradually reduces prostate volume.
Q4. Which patient is most likely to benefit from a 5-alpha-reductase
inhibitor for BPH?
A) Patient with transient urinary frequency from caffeine
B) Patient with normal prostate size and mild symptoms
C) Patient with demonstrable prostatic enlargement and persistent lower
urinary tract symptoms
D) Patient with acute bacterial prostatitis
Correct Answer: C) Patient with demonstrable prostatic enlargement and
, persistent lower urinary tract symptoms
Rationale: 5-alpha-reductase inhibitors are most useful when BPH is
associated with substantial prostatic enlargement.
Q5. Which counseling point is appropriate before initiating
finasteride?
A) Symptom relief is usually complete after the first dose.
B) Improvement may take several months, and sexual adverse effects can
occur.
C) It commonly causes severe hypertension.
D) It should be taken only during episodes of urinary retention.
Correct Answer: B) Improvement may take several months, and sexual
adverse effects can occur.
Rationale: Reduction in prostate size develops gradually, and decreased
libido, erectile dysfunction, or ejaculatory changes can occur.
Q6. What effect can finasteride have on prostate-specific antigen
measurements?
A) It can lower PSA concentrations and must be considered when interpreting
follow-up results.
B) It always doubles PSA.
C) It makes PSA monitoring impossible.
D) It has no effect on PSA.
Correct Answer: A) It can lower PSA concentrations and must be considered
when interpreting follow-up results.
Rationale: 5-alpha-reductase inhibitors decrease PSA, so treatment-related
suppression should be considered when interpreting values.
Q7. Which medication used for BPH is particularly associated with
intraoperative floppy iris syndrome during cataract surgery?
A) Finasteride
B) Dutasteride
C) Tadalafil
D) Tamsulosin
Correct Answer: D) Tamsulosin
Rationale: Alpha-1 blockers, especially tamsulosin, have been associated
with intraoperative floppy iris syndrome.
Q8. Which medication can improve both lower urinary tract
symptoms from BPH and erectile dysfunction in an appropriate
patient?
A) Finasteride only
And Answers SNHU
Q1. Which medication class generally provides relatively rapid
improvement in lower urinary tract symptoms caused by benign
prostatic hyperplasia?
A) 5-alpha-reductase inhibitors
B) Alpha-1 adrenergic antagonists
C) PDE5 inhibitors used only as needed
D) Antimuscarinic agents alone
Correct Answer: B) Alpha-1 adrenergic antagonists
Rationale: Alpha-1 blockers relax smooth muscle in the prostate and
bladder neck and can improve urinary flow and symptoms relatively quickly.
Q2. Which adverse effect is particularly important when initiating an
alpha-1 blocker for BPH?
A) Hyperkalemia
B) Gingival hyperplasia
C) Severe hypoglycemia
D) Orthostatic hypotension and dizziness
Correct Answer: D) Orthostatic hypotension and dizziness
Rationale: Alpha-1 blockade decreases vascular tone and may cause
postural hypotension, particularly after initial doses or dose escalation.
Q3. Finasteride improves BPH primarily through which mechanism?
A) Inhibition of conversion of testosterone to dihydrotestosterone
B) Direct stimulation of bladder contraction
C) Muscarinic receptor blockade
D) Increased testosterone synthesis
Correct Answer: A) Inhibition of conversion of testosterone to
dihydrotestosterone
Rationale: 5-alpha-reductase inhibition lowers prostatic dihydrotestosterone
concentrations and gradually reduces prostate volume.
Q4. Which patient is most likely to benefit from a 5-alpha-reductase
inhibitor for BPH?
A) Patient with transient urinary frequency from caffeine
B) Patient with normal prostate size and mild symptoms
C) Patient with demonstrable prostatic enlargement and persistent lower
urinary tract symptoms
D) Patient with acute bacterial prostatitis
Correct Answer: C) Patient with demonstrable prostatic enlargement and
, persistent lower urinary tract symptoms
Rationale: 5-alpha-reductase inhibitors are most useful when BPH is
associated with substantial prostatic enlargement.
Q5. Which counseling point is appropriate before initiating
finasteride?
A) Symptom relief is usually complete after the first dose.
B) Improvement may take several months, and sexual adverse effects can
occur.
C) It commonly causes severe hypertension.
D) It should be taken only during episodes of urinary retention.
Correct Answer: B) Improvement may take several months, and sexual
adverse effects can occur.
Rationale: Reduction in prostate size develops gradually, and decreased
libido, erectile dysfunction, or ejaculatory changes can occur.
Q6. What effect can finasteride have on prostate-specific antigen
measurements?
A) It can lower PSA concentrations and must be considered when interpreting
follow-up results.
B) It always doubles PSA.
C) It makes PSA monitoring impossible.
D) It has no effect on PSA.
Correct Answer: A) It can lower PSA concentrations and must be considered
when interpreting follow-up results.
Rationale: 5-alpha-reductase inhibitors decrease PSA, so treatment-related
suppression should be considered when interpreting values.
Q7. Which medication used for BPH is particularly associated with
intraoperative floppy iris syndrome during cataract surgery?
A) Finasteride
B) Dutasteride
C) Tadalafil
D) Tamsulosin
Correct Answer: D) Tamsulosin
Rationale: Alpha-1 blockers, especially tamsulosin, have been associated
with intraoperative floppy iris syndrome.
Q8. Which medication can improve both lower urinary tract
symptoms from BPH and erectile dysfunction in an appropriate
patient?
A) Finasteride only
