,NUR 600 Module 6 Advanced Pharmacology 2026/2027 Questions
And Answers SNHU
Q1. Which principle is most important when prescribing medication
for chronic obesity management?
A) Medication should replace nutrition and activity interventions.
B) Pharmacotherapy should be combined with individualized lifestyle and
behavioral treatment.
C) Treatment should stop as soon as any weight loss occurs.
D) Medication selection should be based only on BMI.
Correct Answer: B) Pharmacotherapy should be combined with individualized
lifestyle and behavioral treatment.
Rationale: Obesity is a chronic disease, and medications work best as part
of a comprehensive plan that includes nutrition, physical activity, behavioral
support, and management of related conditions.
Q2. Orlistat promotes weight loss primarily through which
mechanism?
A) Increasing norepinephrine release
B) Activating GLP-1 receptors
C) Blocking opioid receptors
D) Inhibiting gastrointestinal lipases and reducing dietary fat absorption
Correct Answer: D) Inhibiting gastrointestinal lipases and reducing dietary fat
absorption
Rationale: Orlistat inhibits gastric and pancreatic lipases, reducing
hydrolysis and absorption of dietary triglycerides.
Q3. Which adverse-effect pattern is most characteristic of orlistat?
A) Oily stools, fecal urgency, and increased flatulence
B) Severe bradycardia
C) Persistent dry cough
D) Urinary retention
Correct Answer: A) Oily stools, fecal urgency, and increased flatulence
Rationale: Unabsorbed dietary fat remains within the gastrointestinal tract
and can cause steatorrhea, urgency, oily spotting, and flatulence.
Q4. Which nutritional consideration is important during long-term
orlistat therapy?
A) Increase vitamin K intake without monitoring.
B) Avoid all protein.
C) Reduced absorption of fat-soluble vitamins may require appropriate
supplementation.
, D) Increase dietary fat to improve drug absorption.
Correct Answer: C) Reduced absorption of fat-soluble vitamins may require
appropriate supplementation.
Rationale: Orlistat can decrease absorption of vitamins A, D, E, and K.
Q5. Which patient characteristic creates the greatest concern before
prescribing phentermine?
A) Seasonal allergic rhinitis
B) Significant cardiovascular disease or uncontrolled hypertension
C) Mild iron-deficiency anemia
D) Controlled hypothyroidism
Correct Answer: B) Significant cardiovascular disease or uncontrolled
hypertension
Rationale: Phentermine is a sympathomimetic and can increase heart rate
and blood pressure.
Q6. Which adverse effect is commonly associated with
sympathomimetic weight-loss medications?
A) Insomnia and palpitations
B) Severe bradycardia
C) Profound hypoglycemia in all patients
D) Ototoxicity
Correct Answer: A) Insomnia and palpitations
Rationale: Central and peripheral adrenergic stimulation can produce
nervousness, insomnia, tachycardia, and increased blood pressure.
Q7. Which safety concern is particularly important with
phentermine/topiramate therapy in a patient who can become
pregnant?
A) Hyperkalemia
B) Severe neutropenia
C) Fetal harm associated with topiramate exposure
D) Irreversible hearing loss
Correct Answer: D) Fetal harm associated with topiramate exposure
Rationale: Topiramate exposure during pregnancy is associated with
congenital malformation risk, making pregnancy prevention and counseling
important.
Q8. Naltrexone/bupropion should generally be avoided in which
patient?
A) Patient with controlled allergic rhinitis
B) Patient with mild constipation
And Answers SNHU
Q1. Which principle is most important when prescribing medication
for chronic obesity management?
A) Medication should replace nutrition and activity interventions.
B) Pharmacotherapy should be combined with individualized lifestyle and
behavioral treatment.
C) Treatment should stop as soon as any weight loss occurs.
D) Medication selection should be based only on BMI.
Correct Answer: B) Pharmacotherapy should be combined with individualized
lifestyle and behavioral treatment.
Rationale: Obesity is a chronic disease, and medications work best as part
of a comprehensive plan that includes nutrition, physical activity, behavioral
support, and management of related conditions.
Q2. Orlistat promotes weight loss primarily through which
mechanism?
A) Increasing norepinephrine release
B) Activating GLP-1 receptors
C) Blocking opioid receptors
D) Inhibiting gastrointestinal lipases and reducing dietary fat absorption
Correct Answer: D) Inhibiting gastrointestinal lipases and reducing dietary fat
absorption
Rationale: Orlistat inhibits gastric and pancreatic lipases, reducing
hydrolysis and absorption of dietary triglycerides.
Q3. Which adverse-effect pattern is most characteristic of orlistat?
A) Oily stools, fecal urgency, and increased flatulence
B) Severe bradycardia
C) Persistent dry cough
D) Urinary retention
Correct Answer: A) Oily stools, fecal urgency, and increased flatulence
Rationale: Unabsorbed dietary fat remains within the gastrointestinal tract
and can cause steatorrhea, urgency, oily spotting, and flatulence.
Q4. Which nutritional consideration is important during long-term
orlistat therapy?
A) Increase vitamin K intake without monitoring.
B) Avoid all protein.
C) Reduced absorption of fat-soluble vitamins may require appropriate
supplementation.
, D) Increase dietary fat to improve drug absorption.
Correct Answer: C) Reduced absorption of fat-soluble vitamins may require
appropriate supplementation.
Rationale: Orlistat can decrease absorption of vitamins A, D, E, and K.
Q5. Which patient characteristic creates the greatest concern before
prescribing phentermine?
A) Seasonal allergic rhinitis
B) Significant cardiovascular disease or uncontrolled hypertension
C) Mild iron-deficiency anemia
D) Controlled hypothyroidism
Correct Answer: B) Significant cardiovascular disease or uncontrolled
hypertension
Rationale: Phentermine is a sympathomimetic and can increase heart rate
and blood pressure.
Q6. Which adverse effect is commonly associated with
sympathomimetic weight-loss medications?
A) Insomnia and palpitations
B) Severe bradycardia
C) Profound hypoglycemia in all patients
D) Ototoxicity
Correct Answer: A) Insomnia and palpitations
Rationale: Central and peripheral adrenergic stimulation can produce
nervousness, insomnia, tachycardia, and increased blood pressure.
Q7. Which safety concern is particularly important with
phentermine/topiramate therapy in a patient who can become
pregnant?
A) Hyperkalemia
B) Severe neutropenia
C) Fetal harm associated with topiramate exposure
D) Irreversible hearing loss
Correct Answer: D) Fetal harm associated with topiramate exposure
Rationale: Topiramate exposure during pregnancy is associated with
congenital malformation risk, making pregnancy prevention and counseling
important.
Q8. Naltrexone/bupropion should generally be avoided in which
patient?
A) Patient with controlled allergic rhinitis
B) Patient with mild constipation
