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This NURS 6531 Final Exam study guide offers 300 unique multiple-choice
questions covering advanced practice care of adults across the lifespan. Organized
into ten sections, it addresses cardiovascular, respiratory, endocrine,
gastrointestinal, renal, musculoskeletal, dermatologic, and infectious disease
topics, plus preventive care and pharmacokinetics. Each question includes four
options, the correct answer, and a detailed rationale. Designed for Walden
University MSN Family Nurse Practitioner students, this resource reinforces
clinical decision-making and diagnostic reasoning for primary care. It
complements official course materials and helps candidates prepare for the
comprehensive final exam by simulating realistic patient scenarios and evidence-
based management choices.
Section 1: Cardiovascular Disorders (1-45)
1. A 68-year-old African American female presents with blood pressure readings
of 162/98 mmHg and 158/94 mmHg on two separate occasions. She has a BMI of
31 kg/m² and a family history of hypertension and type 2 diabetes. Which
component is MOST critical to include in her focused cardiovascular history?
A. Detailed dietary recall including sodium, potassium, and caffeine intake
B. Assessment of medication adherence, home blood pressure monitoring log
review, and screening for target organ damage symptoms
C. Comprehensive sexual health history including contraceptive use
D. Detailed family pedigree charting extending to second-degree relatives
Answer: B
Rationale: This patient has Stage 2 hypertension (BP >160/100 mmHg per
ACC/AHA 2017 guidelines) with multiple risk factors. The most critical
component is assessing medication adherence, reviewing home BP logs, and
,screening for target organ damage (chest pain, dyspnea, nocturia) to guide urgent
management decisions.
2. A 58-year-old male with a history of hypertension presents with crushing
substernal chest pain radiating to the left jaw. Which is the most likely diagnosis?
A. Pericarditis
B. Angina pectoris
C. Myocardial infarction
D. Pulmonary embolism
Answer: C
Rationale: Crushing substernal chest pain radiating to the jaw is classic for
myocardial infarction. Immediate ECG and troponin levels are indicated.
3. Which medication is first-line therapy for stable angina?
A. Beta-blocker
B. Calcium channel blocker
C. Nitrate
D. ACE inhibitor
Answer: A
Rationale: Beta-blockers are first-line therapy for stable angina, reducing
myocardial oxygen demand by decreasing heart rate and contractility.
4. A patient with heart failure with reduced ejection fraction (HFrEF) should be
prescribed which class of medication to reduce mortality?
A. Beta-blocker
B. Calcium channel blocker
C. Alpha-blocker
D. Diuretic
Answer: A
Rationale: Beta-blockers (carvedilol, metoprolol succinate, bisoprolol) reduce
mortality in HFrEF. They are part of guideline-directed medical therapy.
5. Which of the following are non-modifiable risk factors for cardiovascular
disease? (Select all that apply.)
A. Age
B. Family history
C. Smoking
,D. Gender
Answer: A, B, D
Rationale: Age, family history, and gender are non-modifiable. Smoking is
modifiable.
6. A 68-year-old patient with heart failure reports increasing shortness of breath
and weight gain of 3 kg in one week. What is the most appropriate initial
intervention?
A. Increase diuretic dose
B. Decrease fluid intake
C. Schedule follow-up in one month
D. Order chest X-ray
Answer: A
Rationale: Worsening heart failure symptoms with rapid weight gain indicate fluid
overload. Increasing the diuretic dose is the most appropriate initial intervention.
7. Which medication class is considered first-line therapy for reducing
cardiovascular events in a patient with diabetes and hypertension?
A. ACE inhibitor or ARB
B. Calcium channel blocker
C. Beta-blocker
D. Alpha-blocker
Answer: A
Rationale: ACE inhibitors or ARBs are first-line for patients with diabetes and
hypertension due to their renal protective effects.
8. A patient presents with jugular venous distension, ascites, and peripheral edema.
Which condition is most likely?
A. Left-sided heart failure
B. Right-sided heart failure
C. Pulmonary embolism
D. Pneumonia
Answer: B
Rationale: Right-sided heart failure leads to systemic congestion, resulting in JVD,
ascites, and edema. Pulmonary crackles are more typical of left-sided failure.
, 9. Which finding suggests right-sided heart failure?
A. Pulmonary crackles
B. Orthopnea
C. Jugular venous distension
D. Inspiratory wheezes
Answer: C
Rationale: Right-sided failure leads to systemic congestion, resulting in JVD,
ascites, and edema.
10. A 55-year-old man with hypertension has a BP of 150/92 mmHg on lisinopril
20 mg daily. What is the most appropriate next step?
A. Continue current therapy
B. Add a second antihypertensive agent
C. Discontinue lisinopril
D. Refer to cardiology
Answer: B
Rationale: The patient's BP is above goal on monotherapy. Adding a second agent
(e.g., thiazide diuretic or calcium channel blocker) is appropriate.
11. Which lipid-lowering drug reduces cardiovascular events but does not lower
LDL significantly?
A. Statin
B. Ezetimibe
C. Fibrate
D. Niacin
Answer: C
Rationale: Fibrates reduce triglycerides and cardiovascular events but have
minimal effect on LDL cholesterol.
12. Which medication is first-line for a 54-year-old Black patient with newly
diagnosed hypertension without CKD, diabetes, or albuminuria?
A. ACE inhibitor
B. ARB
C. Thiazide diuretic or calcium channel blocker
D. Beta-blocker
Answer: C