NR 508 Final Review Questions | Nurse
Practitioner Pharmacology |
Comprehensive Study Guide
Nurse practitioner prescriptive authority is regulated by: - correct answer-The
State Board of Nursing for each state
The benefits to the patient of having an Advanced Practice Registered Nurse
(APRN) prescriber include: - correct answer-Nurses care for the patient from a
holistic approach and include the patient in decision making regarding their care.
Clinical judgment in prescribing includes: - correct answer-Consulting nationally
recognized guidelines for disease management
Nurse practitioner practice may thrive under health-care reform because of: -
correct answer-The demonstrated ability of nurse practitioners to control costs
and improve patient outcomes
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This
is critical to prescribing because: - correct answer-Distribution of drugs to target
tissue may be affected.
,Drugs that have a significant first-pass effect: - correct answer-re rapidly
metabolized by the liver and may have little if any desired action
The route of excretion of a volatile drug will likely be the: - correct answer-Bile
and feces
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create
a storage reservoir of the drug. Storage reservoirs: - correct answer-Increase the
length of time a drug is available and active
The NP chooses to give cephalexin every 8 hours based on knowledge of the
drug's: - correct answer-Biological half-life
Azithromycin dosing requires that the first day's dosage be twice those of the
other 4 days of the prescription. This is considered a loading dose. A loading dose:
- correct answer-Rapidly achieves drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a
therapeutic effect is the: - correct answer-Onset of action
Phenytoin requires that a trough level be drawn. Peak and trough levels are done
- correct answer-To determine if a drug is in the therapeutic range
A laboratory result indicates that the peak level for a drug is above the minimum
toxic concentration. This means that the: - correct answer-Concentration will
produce an adverse response
,Drugs that are receptor agonists may demonstrate what property? - correct
answer-Desensitization or downregulation with continuous use
Drugs that are receptor antagonists, such as beta blockers, may cause: - correct
answer-An exaggerated response if abruptly discontinued
Factors that affect gastric drug absorption include: - correct answer-Lipid
solubility of the drug
Drugs administered via IV - correct answer-begin distribution into the body
immediately
When a medication is added to a regimen for a synergistic effect, the combined
effect of the drugs is: - correct answer-Greater than the sum of the effects of
each drug individually
Which of the following statements about bioavailability is true? - correct answer-
Bioavailability issues are especially important for drugs with narrow therapeutic
ranges or sustained-release mechanisms.
Which of the following statements about the major distribution barriers (blood-
brain or fetal-placental) is true? - correct answer-The blood-brain barrier slows
the entry of many drugs into and from brain cells.
Drugs are metabolized mainly by the liver via phase I or phase II reactions. The
purpose of both of these types of reactions is to: - correct answer-Change drug
molecules to a form that an excretory organ can excrete
, Once they have been metabolized by the liver, the metabolites may be:
-More active than the parent drug
-Less active than the parent drug
-Totally "deactivated" so they are excreted without any effect
-All of the above - correct answer-All of the above
All drugs continue to act in the body until they are changed or excreted. The
ability of the body to excrete drugs via the renal system would be increased by: -
correct answer-Unbinding a nonvolatile drug from plasma proteins
Steady state is: - correct answer-When the amount of drug in the body remains
constant
Two different pain medications are given together for pain relief. The drug—drug
interaction is - correct answer-Additive
Actions taken to reduce drug—drug interaction problems include all of the
following EXCEPT: - correct answer-Prescribing a third drug to counteract the
adverse reaction of the combination
. Phase I oxidative-reductive processes of drug metabolism require certain
nutritional elements. Which of the following would reduce or inhibit this process?
-Protein malnutrition
-Iron-deficiency anemia
Practitioner Pharmacology |
Comprehensive Study Guide
Nurse practitioner prescriptive authority is regulated by: - correct answer-The
State Board of Nursing for each state
The benefits to the patient of having an Advanced Practice Registered Nurse
(APRN) prescriber include: - correct answer-Nurses care for the patient from a
holistic approach and include the patient in decision making regarding their care.
Clinical judgment in prescribing includes: - correct answer-Consulting nationally
recognized guidelines for disease management
Nurse practitioner practice may thrive under health-care reform because of: -
correct answer-The demonstrated ability of nurse practitioners to control costs
and improve patient outcomes
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This
is critical to prescribing because: - correct answer-Distribution of drugs to target
tissue may be affected.
,Drugs that have a significant first-pass effect: - correct answer-re rapidly
metabolized by the liver and may have little if any desired action
The route of excretion of a volatile drug will likely be the: - correct answer-Bile
and feces
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create
a storage reservoir of the drug. Storage reservoirs: - correct answer-Increase the
length of time a drug is available and active
The NP chooses to give cephalexin every 8 hours based on knowledge of the
drug's: - correct answer-Biological half-life
Azithromycin dosing requires that the first day's dosage be twice those of the
other 4 days of the prescription. This is considered a loading dose. A loading dose:
- correct answer-Rapidly achieves drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a
therapeutic effect is the: - correct answer-Onset of action
Phenytoin requires that a trough level be drawn. Peak and trough levels are done
- correct answer-To determine if a drug is in the therapeutic range
A laboratory result indicates that the peak level for a drug is above the minimum
toxic concentration. This means that the: - correct answer-Concentration will
produce an adverse response
,Drugs that are receptor agonists may demonstrate what property? - correct
answer-Desensitization or downregulation with continuous use
Drugs that are receptor antagonists, such as beta blockers, may cause: - correct
answer-An exaggerated response if abruptly discontinued
Factors that affect gastric drug absorption include: - correct answer-Lipid
solubility of the drug
Drugs administered via IV - correct answer-begin distribution into the body
immediately
When a medication is added to a regimen for a synergistic effect, the combined
effect of the drugs is: - correct answer-Greater than the sum of the effects of
each drug individually
Which of the following statements about bioavailability is true? - correct answer-
Bioavailability issues are especially important for drugs with narrow therapeutic
ranges or sustained-release mechanisms.
Which of the following statements about the major distribution barriers (blood-
brain or fetal-placental) is true? - correct answer-The blood-brain barrier slows
the entry of many drugs into and from brain cells.
Drugs are metabolized mainly by the liver via phase I or phase II reactions. The
purpose of both of these types of reactions is to: - correct answer-Change drug
molecules to a form that an excretory organ can excrete
, Once they have been metabolized by the liver, the metabolites may be:
-More active than the parent drug
-Less active than the parent drug
-Totally "deactivated" so they are excreted without any effect
-All of the above - correct answer-All of the above
All drugs continue to act in the body until they are changed or excreted. The
ability of the body to excrete drugs via the renal system would be increased by: -
correct answer-Unbinding a nonvolatile drug from plasma proteins
Steady state is: - correct answer-When the amount of drug in the body remains
constant
Two different pain medications are given together for pain relief. The drug—drug
interaction is - correct answer-Additive
Actions taken to reduce drug—drug interaction problems include all of the
following EXCEPT: - correct answer-Prescribing a third drug to counteract the
adverse reaction of the combination
. Phase I oxidative-reductive processes of drug metabolism require certain
nutritional elements. Which of the following would reduce or inhibit this process?
-Protein malnutrition
-Iron-deficiency anemia
