NR 508 Week 6 Ultimate Exam –
2026/2027 Updated Questions, Answers &
Rationales
Henry presents to clinic with a significantly swollen, painful great toe and is
diagnosed with gout. Of the following, which would be the best treatment for
Henry?
1. High-dose colchicine
2. Low-dose colchicine
3. High-dose aspirin
4. Acetaminophen with codeine - correct answer-2. Low-dose colchicine
Patient education when prescribing colchicine includes:
1. Colchicine may be constipating.
2. Colchicine always causes some degree of diarrhea.
3. Mild muscle weakness is normal.
4. Moderate amounts of alcohol are safe with colchicine. - correct answer-2.
Colchicine always causes some degree of diarrhea.
,Larry is taking allopurinol to prevent gout. Monitoring of a patient who is taking
allopurinol includes:
1. Complete blood count
2. Blood glucose
3. C-reactive protein
4. BUN, creatinine, and creatinine clearance - correct answer-4. BUN, creatinine,
and creatinine clearance
Phil is starting treatment with febuxostat (Uloric). Education of patients starting
febuxostat includes:
1. Gout may worsen with therapy.
2. Febuxostat may cause severe diarrhea.
3. He should consume a high-calcium diet.
4. He will need frequent CBC monitoring. - correct answer-1. Gout may worsen
with therapy.
Sallie has been taking 10 mg per day of prednisone for the past 6 months. She
should be assessed for:
1. Gout
2. Iron deficiency anemia
3. Osteoporosis
4. Renal dysfunction - correct answer-3. Osteoporosis
Patients whose total dose of prednisone will exceed 1 gram will most likely need a
second prescription for:
1. Metformin, a biguanide to prevent diabetes
, 2. Omeprazole, a proton pump inhibitor to prevent peptic ulcer disease
3. Naproxen, an NSAID to treat joint pain
4. Furosemide, a diuretic to treat fluid retention - correct answer-2. Omeprazole,
a proton pump inhibitor to prevent peptic ulcer disease
Daniel has been on 60 mg of prednisone for 10 days to treat a severe asthma
exacerbation. It is time to discontinue the prednisone. How is prednisone
discontinued?
1. Patients with asthma are transitioned directly off the prednisone onto inhaled
corticosteroids.
2. Prednisone can be abruptly discontinued with no adverse effects.
3. Develop a tapering schedule to slowly wean Daniel off the prednisone.
4. Substitute the prednisone with another anti-inflammatory such as ibuprofen. -
correct answer-3. Develop a tapering schedule to slowly wean Daniel off the
prednisone.
Patients with rheumatoid arthritis who are on chronic low-dose prednisone will
need co-treatment with which medications to prevent further adverse effects?
1. A bisphosphonate
2. Calcium supplementation
3. Vitamin D
4. All of the above - correct answer-4. All of the above
Patients who are on or who will be starting chronic corticosteroid therapy need
monitoring of:
1. Serum glucose
2. Stool culture
2026/2027 Updated Questions, Answers &
Rationales
Henry presents to clinic with a significantly swollen, painful great toe and is
diagnosed with gout. Of the following, which would be the best treatment for
Henry?
1. High-dose colchicine
2. Low-dose colchicine
3. High-dose aspirin
4. Acetaminophen with codeine - correct answer-2. Low-dose colchicine
Patient education when prescribing colchicine includes:
1. Colchicine may be constipating.
2. Colchicine always causes some degree of diarrhea.
3. Mild muscle weakness is normal.
4. Moderate amounts of alcohol are safe with colchicine. - correct answer-2.
Colchicine always causes some degree of diarrhea.
,Larry is taking allopurinol to prevent gout. Monitoring of a patient who is taking
allopurinol includes:
1. Complete blood count
2. Blood glucose
3. C-reactive protein
4. BUN, creatinine, and creatinine clearance - correct answer-4. BUN, creatinine,
and creatinine clearance
Phil is starting treatment with febuxostat (Uloric). Education of patients starting
febuxostat includes:
1. Gout may worsen with therapy.
2. Febuxostat may cause severe diarrhea.
3. He should consume a high-calcium diet.
4. He will need frequent CBC monitoring. - correct answer-1. Gout may worsen
with therapy.
Sallie has been taking 10 mg per day of prednisone for the past 6 months. She
should be assessed for:
1. Gout
2. Iron deficiency anemia
3. Osteoporosis
4. Renal dysfunction - correct answer-3. Osteoporosis
Patients whose total dose of prednisone will exceed 1 gram will most likely need a
second prescription for:
1. Metformin, a biguanide to prevent diabetes
, 2. Omeprazole, a proton pump inhibitor to prevent peptic ulcer disease
3. Naproxen, an NSAID to treat joint pain
4. Furosemide, a diuretic to treat fluid retention - correct answer-2. Omeprazole,
a proton pump inhibitor to prevent peptic ulcer disease
Daniel has been on 60 mg of prednisone for 10 days to treat a severe asthma
exacerbation. It is time to discontinue the prednisone. How is prednisone
discontinued?
1. Patients with asthma are transitioned directly off the prednisone onto inhaled
corticosteroids.
2. Prednisone can be abruptly discontinued with no adverse effects.
3. Develop a tapering schedule to slowly wean Daniel off the prednisone.
4. Substitute the prednisone with another anti-inflammatory such as ibuprofen. -
correct answer-3. Develop a tapering schedule to slowly wean Daniel off the
prednisone.
Patients with rheumatoid arthritis who are on chronic low-dose prednisone will
need co-treatment with which medications to prevent further adverse effects?
1. A bisphosphonate
2. Calcium supplementation
3. Vitamin D
4. All of the above - correct answer-4. All of the above
Patients who are on or who will be starting chronic corticosteroid therapy need
monitoring of:
1. Serum glucose
2. Stool culture
