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Question 1
What is the most common indication for genetic counselling?
• A. Maternal Age
• B. Drug exposure during the first trimester
• C. Increased maternal alpha-fetoprotein
• D. History of previous still birth
Correct Answer: A. Maternal Age
Rationale: Advanced maternal age is the most common indication for genetic
counseling due to increased risk of chromosomal abnormalities.
Question 2
The FNP schedules a 38-year-old primigravida (first time pregnancy) for an
amniocentesis at 16 weeks gestation. The FNP would explain that the
purpose of this procedure is to:
• A. Assess for the possibility of twins
• B. Determine bilirubin level
• C. Perform genetic studies
• D. Assess L/S ratio
Correct Answer: C. Perform genetic studies
Rationale: This woman's age puts her at risk for Down Syndrome.
,Question 3
In the most commonly seen form of Turner Syndrome, how is the X
chromosome affected?
• A. Each cell has only one X chromosome
• B. Some cells have two X chromosomes, while other cells have only one.
• C. Each cell has two X chromosomes, but part of the chromosome is
missing.
• D. Each cell has an extra X chromosome.
Correct Answer: A. Each cell has only one X chromosome
Rationale: 45% of persons with Turner Syndrome have monosomy X meaning
there is only one copy of the X chromosome in each cell.
Question 4
The FNP is assessing a newborn who is demonstrating a high-pitched cry,
microcephaly, hypertelorism, hypotonia, and a low birth weight. The FNP
would suspect which of the following genetic conditions?
• A. Down Syndrome
• B. Cri du chat
• C. Charge syndrome
• D. Duncan disease
Correct Answer: B. Cri du chat
Rationale: The clinical symptoms of cri du chat syndrome usually include a
high-pitched cat-like cry, mental retardation, delayed development, distinctive
facial features, small head size (microcephaly), widely-spaced eyes
(hypertelorism), low birth weight and weak muscle tone (hypotonia) in infancy.
, Question 5
When explaining the types of adaptive immunity, the FNP student is aware
that:
• A. Adaptive immunity is a cell-mediated immune response which is
carried out by T cells and B cells.
• B. Adaptive immunity is the level of immunity that all persons are born
with.
• C. Adaptive immunity occurs when antibodies are passed from the
mother to the fetus.
• D. Adaptive immunity occurs through immunization
Correct Answer: A. Adaptive immunity is a cell-mediated immune response
which is carried out by T cells and B cells.
Rationale: There are two types of adaptive immunity responses: the cell-
mediated immune response, which is carried out by T cells, and the humoral
immune response, which is controlled by activated B cells and antibodies.
Question 6
A woman has sustained a traumatic brain injury. She is able to follow simple
commands and can manipulate objects. Which term describes this state?
• A. Coma
• B. Persistent vegetative state
• C. Minimally conscious
• D. Locked-in syndrome
Correct Answer: C. Minimally conscious
Rationale: When responses to the environment are seen, the patient is said to
be in a minimally conscious state.
Question 7