BIOL 3201 Immunology –
Questions and Answers | Final
Exam Preparation | Thompson
Rivers University | 2026–2027
Description: This comprehensive revision set covers innate
immunity, adaptive immunity, antigens, antibodies,
complement, MHC, T cell and B cell biology, hypersensitivity,
vaccines, transplantation, autoimmunity, immunodeficiency,
and clinical immunology for BIOL 3201 Immunology at
Thompson Rivers University.
Keywords: Immunology, innate immunity, adaptive immunity,
antibodies, T cells, B cells, MHC, complement, cytokines,
hypersensitivity, autoimmunity, vaccines, transplantation,
immunology MCQ, BIOL 3201, TRU.
1. Which of the following is a primary lymphoid organ?
A. Spleen
B. Lymph node
C. Bone marrow ✅
D. Tonsil
2. Which cells are the first responders during innate immunity?
A. B cells
B. Macrophages ✅
,C. Plasma cells
D. Memory T cells
3. What is the main function of dendritic cells?
A. Produce antibodies
B. Phagocytose pathogens and present antigens ✅
C. Kill infected cells directly
D. Release histamine
4. Which immunoglobulin is most abundant in serum?
A. IgA
B. IgM
C. IgG ✅
D. IgE
5. Which antibody class is found in mucosal secretions?
A. IgG
B. IgA ✅
C. IgD
D. IgM
6. Which antibody is first produced in a primary immune response?
A. IgG
B. IgA
C. IgM ✅
D. IgE
7. What is the function of IgE?
A. Opsonization
B. Allergy and parasite defense ✅
C. Complement activation
D. Mucosal immunity
,8. Which cells produce antibodies?
A. T cells
B. Plasma cells ✅
C. Macrophages
D. Neutrophils
9. Where do T cells mature?
A. Bone marrow
B. Thymus ✅
C. Spleen
D. Lymph nodes
10. Which MHC class presents antigens to CD8+ T cells?
A. MHC I ✅
B. MHC II
C. MHC III
D. CD4
11. Which MHC class presents antigens to CD4+ T cells?
A. MHC I
B. MHC II ✅
C. MHC III
D. CD8
12. What is the role of CD4+ T cells?
A. Kill infected cells
B. Help activate B cells and macrophages ✅
C. Produce antibodies
D. Release histamine
13. What is the role of CD8+ T cells?
A. Kill infected cells ✅
B. Help B cells
, C. Produce antibodies
D. Phagocytose bacteria
14. Which cytokine is produced by Th1 cells?
A. IL-4
B. IFN-γ ✅
C. IL-5
D. IL-10
15. Which cytokine is produced by Th2 cells?
A. IFN-γ
B. IL-4 ✅
C. TNF-α
D. IL-12
16. What is the function of complement protein C3b?
A. Opsonization ✅
B. Histamine release
C. Antibody production
D. Antigen presentation
17. Which complement pathway is activated by antibodies?
A. Classical ✅
B. Alternative
C. Lectin
D. Intrinsic
18. Which complement pathway is activated by microbial surfaces?
A. Classical
B. Alternative ✅
C. Lectin
D. Extrinsic
Questions and Answers | Final
Exam Preparation | Thompson
Rivers University | 2026–2027
Description: This comprehensive revision set covers innate
immunity, adaptive immunity, antigens, antibodies,
complement, MHC, T cell and B cell biology, hypersensitivity,
vaccines, transplantation, autoimmunity, immunodeficiency,
and clinical immunology for BIOL 3201 Immunology at
Thompson Rivers University.
Keywords: Immunology, innate immunity, adaptive immunity,
antibodies, T cells, B cells, MHC, complement, cytokines,
hypersensitivity, autoimmunity, vaccines, transplantation,
immunology MCQ, BIOL 3201, TRU.
1. Which of the following is a primary lymphoid organ?
A. Spleen
B. Lymph node
C. Bone marrow ✅
D. Tonsil
2. Which cells are the first responders during innate immunity?
A. B cells
B. Macrophages ✅
,C. Plasma cells
D. Memory T cells
3. What is the main function of dendritic cells?
A. Produce antibodies
B. Phagocytose pathogens and present antigens ✅
C. Kill infected cells directly
D. Release histamine
4. Which immunoglobulin is most abundant in serum?
A. IgA
B. IgM
C. IgG ✅
D. IgE
5. Which antibody class is found in mucosal secretions?
A. IgG
B. IgA ✅
C. IgD
D. IgM
6. Which antibody is first produced in a primary immune response?
A. IgG
B. IgA
C. IgM ✅
D. IgE
7. What is the function of IgE?
A. Opsonization
B. Allergy and parasite defense ✅
C. Complement activation
D. Mucosal immunity
,8. Which cells produce antibodies?
A. T cells
B. Plasma cells ✅
C. Macrophages
D. Neutrophils
9. Where do T cells mature?
A. Bone marrow
B. Thymus ✅
C. Spleen
D. Lymph nodes
10. Which MHC class presents antigens to CD8+ T cells?
A. MHC I ✅
B. MHC II
C. MHC III
D. CD4
11. Which MHC class presents antigens to CD4+ T cells?
A. MHC I
B. MHC II ✅
C. MHC III
D. CD8
12. What is the role of CD4+ T cells?
A. Kill infected cells
B. Help activate B cells and macrophages ✅
C. Produce antibodies
D. Release histamine
13. What is the role of CD8+ T cells?
A. Kill infected cells ✅
B. Help B cells
, C. Produce antibodies
D. Phagocytose bacteria
14. Which cytokine is produced by Th1 cells?
A. IL-4
B. IFN-γ ✅
C. IL-5
D. IL-10
15. Which cytokine is produced by Th2 cells?
A. IFN-γ
B. IL-4 ✅
C. TNF-α
D. IL-12
16. What is the function of complement protein C3b?
A. Opsonization ✅
B. Histamine release
C. Antibody production
D. Antigen presentation
17. Which complement pathway is activated by antibodies?
A. Classical ✅
B. Alternative
C. Lectin
D. Intrinsic
18. Which complement pathway is activated by microbial surfaces?
A. Classical
B. Alternative ✅
C. Lectin
D. Extrinsic
