Lehne's Pharmacology for Nursing
Care
12th Edition
Author(s)Jacqueline Rosenjack
Burchum; Laura D. Rosenthal
TEST BANK
,
,Question 1 — Easy — Multiple Choice
A patient is prescribed acyclovir for a recurrent herpes
simplex virus infection. Which statement best describes the
therapeutic action of acyclovir?
A. It prevents viral attachment to host cells.
B. It inhibits viral DNA synthesis after activation in infected cells.
C. It destroys viral RNA before the virus enters the cell.
D. It stimulates bacterial antibodies that neutralize the virus.
Correct Answer:
B. It inhibits viral DNA synthesis after activation in infected cells.
Rationale:
Acyclovir is activated primarily in infected cells and inhibits viral
DNA polymerase, reducing viral replication. It does not directly
destroy viral RNA, prevent initial attachment, or stimulate
antibacterial antibodies.
Question 2 — Easy — Multiple Choice
A nurse is teaching a patient who is beginning oral acyclovir.
Which instruction is most appropriate?
A. "Stop taking the medication as soon as the lesions begin to
heal."
B. "Take the medication only when pain becomes severe."
C. "Maintain adequate fluid intake unless fluid restriction has been
prescribed."
D. "Avoid all foods containing carbohydrates while taking this
medication."
Correct Answer:
C. "Maintain adequate fluid intake unless fluid restriction has been
prescribed."
, Rationale:
Adequate hydration is important during acyclovir therapy because
renal adverse effects can occur, particularly with inadequate
hydration. The medication should be taken as prescribed rather
than stopped when symptoms improve, and the other instructions
are not relevant to acyclovir therapy.
Question 3 — Easy — Multiple Choice
Which medication is specifically used to treat infections
caused by cytomegalovirus (CMV)?
A. Ganciclovir
B. Oseltamivir
C. Zanamivir
D. Ribavirin
Correct Answer:
A. Ganciclovir
Rationale:
Ganciclovir is an antiviral agent used for CMV infections.
Oseltamivir and zanamivir are used for influenza, while ribavirin
has activity against selected viral infections but is not the primary
medication represented by this question for CMV treatment.
Question 4 — Easy — Multiple Choice
A patient asks why oseltamivir was prescribed after
developing influenza symptoms. Which response by the
nurse is most accurate?
A. "It is an antibiotic that prevents secondary bacterial infections."
B. "It interferes with influenza virus replication and can reduce the
Care
12th Edition
Author(s)Jacqueline Rosenjack
Burchum; Laura D. Rosenthal
TEST BANK
,
,Question 1 — Easy — Multiple Choice
A patient is prescribed acyclovir for a recurrent herpes
simplex virus infection. Which statement best describes the
therapeutic action of acyclovir?
A. It prevents viral attachment to host cells.
B. It inhibits viral DNA synthesis after activation in infected cells.
C. It destroys viral RNA before the virus enters the cell.
D. It stimulates bacterial antibodies that neutralize the virus.
Correct Answer:
B. It inhibits viral DNA synthesis after activation in infected cells.
Rationale:
Acyclovir is activated primarily in infected cells and inhibits viral
DNA polymerase, reducing viral replication. It does not directly
destroy viral RNA, prevent initial attachment, or stimulate
antibacterial antibodies.
Question 2 — Easy — Multiple Choice
A nurse is teaching a patient who is beginning oral acyclovir.
Which instruction is most appropriate?
A. "Stop taking the medication as soon as the lesions begin to
heal."
B. "Take the medication only when pain becomes severe."
C. "Maintain adequate fluid intake unless fluid restriction has been
prescribed."
D. "Avoid all foods containing carbohydrates while taking this
medication."
Correct Answer:
C. "Maintain adequate fluid intake unless fluid restriction has been
prescribed."
, Rationale:
Adequate hydration is important during acyclovir therapy because
renal adverse effects can occur, particularly with inadequate
hydration. The medication should be taken as prescribed rather
than stopped when symptoms improve, and the other instructions
are not relevant to acyclovir therapy.
Question 3 — Easy — Multiple Choice
Which medication is specifically used to treat infections
caused by cytomegalovirus (CMV)?
A. Ganciclovir
B. Oseltamivir
C. Zanamivir
D. Ribavirin
Correct Answer:
A. Ganciclovir
Rationale:
Ganciclovir is an antiviral agent used for CMV infections.
Oseltamivir and zanamivir are used for influenza, while ribavirin
has activity against selected viral infections but is not the primary
medication represented by this question for CMV treatment.
Question 4 — Easy — Multiple Choice
A patient asks why oseltamivir was prescribed after
developing influenza symptoms. Which response by the
nurse is most accurate?
A. "It is an antibiotic that prevents secondary bacterial infections."
B. "It interferes with influenza virus replication and can reduce the
