,NSG 3280 EXAM 2 - Original Practice Study Guide
NSG 3280 Exam 2 |Pathophysiology I | 2026
Update |100% Correct – Galen College
1. Which mechanism best explains atopic dermatitis?
A) Deep bacterial tissue destruction
B) Skin-barrier dysfunction with immune-mediated inflammation
C) Autoimmune destruction of melanocytes
D) Isolated vascular occlusion
Correct Answer: Skin-barrier dysfunction with immune-mediated inflammation
Rationale: Atopic dermatitis combines impaired epidermal barrier function with dysregulated immune
responses, producing chronic pruritic inflammation.
2. A nurse is interpreting the mechanism behind this disorder. which mechanism best explains atopic
dermatitis?
A) Isolated vascular occlusion
B) Deep bacterial tissue destruction
C) Autoimmune destruction of melanocytes
D) Skin-barrier dysfunction with immune-mediated inflammation
Correct Answer: Skin-barrier dysfunction with immune-mediated inflammation
Rationale: Atopic dermatitis combines impaired epidermal barrier function with dysregulated immune
responses, producing chronic pruritic inflammation. Clinically, the mechanism should be linked to expected
manifestations, disease progression, risk factors, and the physiologic consequences of impaired tissue or
organ function.
3. During clinical assessment, which explanation best applies? Which mechanism best explains atopic
dermatitis?
A) Autoimmune destruction of melanocytes
B) Deep bacterial tissue destruction
C) Skin-barrier dysfunction with immune-mediated inflammation
D) Isolated vascular occlusion
Correct Answer: Skin-barrier dysfunction with immune-mediated inflammation
Rationale: Atopic dermatitis combines impaired epidermal barrier function with dysregulated immune
responses, producing chronic pruritic inflammation. Clinically, the mechanism should be linked to expected
manifestations, disease progression, risk factors, and the physiologic consequences of impaired tissue or
organ function.
4. A patient presents with findings related to this concept. Which mechanism best explains atopic
dermatitis?
A) Skin-barrier dysfunction with immune-mediated inflammation
B) Deep bacterial tissue destruction
C) Autoimmune destruction of melanocytes
Page 2
, NSG 3280 EXAM 2 - Original Practice Study Guide
D) Isolated vascular occlusion
Correct Answer: Skin-barrier dysfunction with immune-mediated inflammation
Rationale: Atopic dermatitis combines impaired epidermal barrier function with dysregulated immune
responses, producing chronic pruritic inflammation. Clinically, the mechanism should be linked to expected
manifestations, disease progression, risk factors, and the physiologic consequences of impaired tissue or
organ function.
5. Which lesion pattern is most typical of psoriasis?
A) Honey-colored crusts
B) Well-demarcated erythematous plaques with silvery scale
C) Painless black eschar
D) Linear burrows
Correct Answer: Well-demarcated erythematous plaques with silvery scale
Rationale: Psoriasis is an immune-mediated disorder with accelerated keratinocyte turnover, producing sharply
demarcated plaques and scale.
6. A nurse is interpreting the mechanism behind this disorder. which lesion pattern is most typical of
psoriasis?
A) Painless black eschar
B) Honey-colored crusts
C) Well-demarcated erythematous plaques with silvery scale
D) Linear burrows
Correct Answer: Well-demarcated erythematous plaques with silvery scale
Rationale: Psoriasis is an immune-mediated disorder with accelerated keratinocyte turnover, producing sharply
demarcated plaques and scale. Clinically, the mechanism should be linked to expected manifestations, disease
progression, risk factors, and the physiologic consequences of impaired tissue or organ function.
7. During clinical assessment, which explanation best applies? Which lesion pattern is most typical of
psoriasis?
A) Honey-colored crusts
B) Well-demarcated erythematous plaques with silvery scale
C) Painless black eschar
D) Linear burrows
Correct Answer: Well-demarcated erythematous plaques with silvery scale
Rationale: Psoriasis is an immune-mediated disorder with accelerated keratinocyte turnover, producing sharply
demarcated plaques and scale. Clinically, the mechanism should be linked to expected manifestations, disease
progression, risk factors, and the physiologic consequences of impaired tissue or organ function.
8. A patient presents with findings related to this concept. Which lesion pattern is most typical of
psoriasis?
A) Well-demarcated erythematous plaques with silvery scale
B) Honey-colored crusts
C) Painless black eschar
Page 3
NSG 3280 Exam 2 |Pathophysiology I | 2026
Update |100% Correct – Galen College
1. Which mechanism best explains atopic dermatitis?
A) Deep bacterial tissue destruction
B) Skin-barrier dysfunction with immune-mediated inflammation
C) Autoimmune destruction of melanocytes
D) Isolated vascular occlusion
Correct Answer: Skin-barrier dysfunction with immune-mediated inflammation
Rationale: Atopic dermatitis combines impaired epidermal barrier function with dysregulated immune
responses, producing chronic pruritic inflammation.
2. A nurse is interpreting the mechanism behind this disorder. which mechanism best explains atopic
dermatitis?
A) Isolated vascular occlusion
B) Deep bacterial tissue destruction
C) Autoimmune destruction of melanocytes
D) Skin-barrier dysfunction with immune-mediated inflammation
Correct Answer: Skin-barrier dysfunction with immune-mediated inflammation
Rationale: Atopic dermatitis combines impaired epidermal barrier function with dysregulated immune
responses, producing chronic pruritic inflammation. Clinically, the mechanism should be linked to expected
manifestations, disease progression, risk factors, and the physiologic consequences of impaired tissue or
organ function.
3. During clinical assessment, which explanation best applies? Which mechanism best explains atopic
dermatitis?
A) Autoimmune destruction of melanocytes
B) Deep bacterial tissue destruction
C) Skin-barrier dysfunction with immune-mediated inflammation
D) Isolated vascular occlusion
Correct Answer: Skin-barrier dysfunction with immune-mediated inflammation
Rationale: Atopic dermatitis combines impaired epidermal barrier function with dysregulated immune
responses, producing chronic pruritic inflammation. Clinically, the mechanism should be linked to expected
manifestations, disease progression, risk factors, and the physiologic consequences of impaired tissue or
organ function.
4. A patient presents with findings related to this concept. Which mechanism best explains atopic
dermatitis?
A) Skin-barrier dysfunction with immune-mediated inflammation
B) Deep bacterial tissue destruction
C) Autoimmune destruction of melanocytes
Page 2
, NSG 3280 EXAM 2 - Original Practice Study Guide
D) Isolated vascular occlusion
Correct Answer: Skin-barrier dysfunction with immune-mediated inflammation
Rationale: Atopic dermatitis combines impaired epidermal barrier function with dysregulated immune
responses, producing chronic pruritic inflammation. Clinically, the mechanism should be linked to expected
manifestations, disease progression, risk factors, and the physiologic consequences of impaired tissue or
organ function.
5. Which lesion pattern is most typical of psoriasis?
A) Honey-colored crusts
B) Well-demarcated erythematous plaques with silvery scale
C) Painless black eschar
D) Linear burrows
Correct Answer: Well-demarcated erythematous plaques with silvery scale
Rationale: Psoriasis is an immune-mediated disorder with accelerated keratinocyte turnover, producing sharply
demarcated plaques and scale.
6. A nurse is interpreting the mechanism behind this disorder. which lesion pattern is most typical of
psoriasis?
A) Painless black eschar
B) Honey-colored crusts
C) Well-demarcated erythematous plaques with silvery scale
D) Linear burrows
Correct Answer: Well-demarcated erythematous plaques with silvery scale
Rationale: Psoriasis is an immune-mediated disorder with accelerated keratinocyte turnover, producing sharply
demarcated plaques and scale. Clinically, the mechanism should be linked to expected manifestations, disease
progression, risk factors, and the physiologic consequences of impaired tissue or organ function.
7. During clinical assessment, which explanation best applies? Which lesion pattern is most typical of
psoriasis?
A) Honey-colored crusts
B) Well-demarcated erythematous plaques with silvery scale
C) Painless black eschar
D) Linear burrows
Correct Answer: Well-demarcated erythematous plaques with silvery scale
Rationale: Psoriasis is an immune-mediated disorder with accelerated keratinocyte turnover, producing sharply
demarcated plaques and scale. Clinically, the mechanism should be linked to expected manifestations, disease
progression, risk factors, and the physiologic consequences of impaired tissue or organ function.
8. A patient presents with findings related to this concept. Which lesion pattern is most typical of
psoriasis?
A) Well-demarcated erythematous plaques with silvery scale
B) Honey-colored crusts
C) Painless black eschar
Page 3
