NSG 552 Psychopharmacology Exam 2 Complete Test
Bank: 300 Questions with Correct Answers, NGN Case
Scenarios & Detailed Rationales 2026/2027 | Practice
Study Guide | Guaranteed Pass
1. Which medication is first-line for alcohol withdrawal to prevent seizures
and delirium tremens?
A) Naltrexone
B) Lorazepam
C) Disulfiram
D) Acamprosate
Answer: B
Rationale: Benzodiazepines are first-line for alcohol withdrawal to prevent
seizures and DTs.
2. A patient on disulfiram drinks alcohol and develops flushing, vomiting,
and hypotension. What is this reaction?
A) Serotonin syndrome
B) Acetaldehyde syndrome
C) Neuroleptic malignant syndrome
D) Anticholinergic crisis
Answer: B
,Rationale: Disulfiram blocks aldehyde dehydrogenase; acetaldehyde accumulates
causing severe reaction.
3. Which medication is used for opioid use disorder as a partial agonist?
A) Methadone
B) Buprenorphine
C) Naltrexone
D) Disulfiram
Answer: B
Rationale: Buprenorphine is a partial mu agonist; reduces cravings and withdrawal
with a ceiling effect.
4. A patient on buprenorphine/naloxone (Suboxone) should be instructed to:
A) Inject the medication
B) Place the film under the tongue and let it dissolve
C) Swallow the tablet whole
D) Chew the tablet
Answer: B
Rationale: Suboxone is sublingual; swallowing reduces absorption and naloxone
causes withdrawal if injected.
5. Which medication is used for opioid overdose?
2
,A) Naltrexone
B) Naloxone
C) Buprenorphine
D) Methadone
Answer: B
Rationale: Naloxone is an opioid antagonist used for acute overdose; short half-
life may require repeat dosing.
6. Which medication is used for alcohol use disorder to reduce craving?
A) Disulfiram
B) Naltrexone
C) Lorazepam
D) Thiamine
Answer: B
Rationale: Naltrexone reduces alcohol craving by blocking opioid receptors; also
used for opioid use disorder.
7. A patient on naltrexone for alcohol use disorder should be monitored for:
A) Hypertension
B) Hepatotoxicity
C) Bradycardia
D) Hyperglycemia
Answer: B
3
, Rationale: Naltrexone can cause liver enzyme elevation; monitor LFTs at baseline
and periodically.
8. Which medication is used for opioid use disorder as a full agonist?
A) Buprenorphine
B) Methadone
C) Naltrexone
D) Naloxone
Answer: B
Rationale: Methadone is a full mu agonist used for maintenance; requires daily
dosing and monitoring for QT prolongation.
9. A patient on methadone reports palpitations. Which ECG finding is
concerning?
A) Sinus tachycardia
B) QT prolongation
C) ST elevation
D) U waves
Answer: B
Rationale: Methadone can prolong QT interval; monitor ECG and electrolytes.
4
Bank: 300 Questions with Correct Answers, NGN Case
Scenarios & Detailed Rationales 2026/2027 | Practice
Study Guide | Guaranteed Pass
1. Which medication is first-line for alcohol withdrawal to prevent seizures
and delirium tremens?
A) Naltrexone
B) Lorazepam
C) Disulfiram
D) Acamprosate
Answer: B
Rationale: Benzodiazepines are first-line for alcohol withdrawal to prevent
seizures and DTs.
2. A patient on disulfiram drinks alcohol and develops flushing, vomiting,
and hypotension. What is this reaction?
A) Serotonin syndrome
B) Acetaldehyde syndrome
C) Neuroleptic malignant syndrome
D) Anticholinergic crisis
Answer: B
,Rationale: Disulfiram blocks aldehyde dehydrogenase; acetaldehyde accumulates
causing severe reaction.
3. Which medication is used for opioid use disorder as a partial agonist?
A) Methadone
B) Buprenorphine
C) Naltrexone
D) Disulfiram
Answer: B
Rationale: Buprenorphine is a partial mu agonist; reduces cravings and withdrawal
with a ceiling effect.
4. A patient on buprenorphine/naloxone (Suboxone) should be instructed to:
A) Inject the medication
B) Place the film under the tongue and let it dissolve
C) Swallow the tablet whole
D) Chew the tablet
Answer: B
Rationale: Suboxone is sublingual; swallowing reduces absorption and naloxone
causes withdrawal if injected.
5. Which medication is used for opioid overdose?
2
,A) Naltrexone
B) Naloxone
C) Buprenorphine
D) Methadone
Answer: B
Rationale: Naloxone is an opioid antagonist used for acute overdose; short half-
life may require repeat dosing.
6. Which medication is used for alcohol use disorder to reduce craving?
A) Disulfiram
B) Naltrexone
C) Lorazepam
D) Thiamine
Answer: B
Rationale: Naltrexone reduces alcohol craving by blocking opioid receptors; also
used for opioid use disorder.
7. A patient on naltrexone for alcohol use disorder should be monitored for:
A) Hypertension
B) Hepatotoxicity
C) Bradycardia
D) Hyperglycemia
Answer: B
3
, Rationale: Naltrexone can cause liver enzyme elevation; monitor LFTs at baseline
and periodically.
8. Which medication is used for opioid use disorder as a full agonist?
A) Buprenorphine
B) Methadone
C) Naltrexone
D) Naloxone
Answer: B
Rationale: Methadone is a full mu agonist used for maintenance; requires daily
dosing and monitoring for QT prolongation.
9. A patient on methadone reports palpitations. Which ECG finding is
concerning?
A) Sinus tachycardia
B) QT prolongation
C) ST elevation
D) U waves
Answer: B
Rationale: Methadone can prolong QT interval; monitor ECG and electrolytes.
4
