COMLEX LEVEL 1 ACTUAL QUESTIONS WITH
VERIFIED SOLUTIONS
◉ Hypothalamus nuclei: Dorsomedial.
Answer: stim: sham rage
lesion: decreased aggression and feeding
◉ Hypothalamus nuclei:
Anterior.
Answer: Funct: Cooling, parasympathetic (think AC =
Anterior/Cooling)
Stim: Panting or sweating
Lesion: difficulty lowering body temp
◉ Hypothalamus nuclei:
Lateral.
Answer: Funct: Hunger
,Stim: Increased feeding (ghrelin)
lesion: decreased feeding (inhibit = leptin)
◉ Hypothalamus nuclei:
Ventromedial.
Answer: Funct: Satiety
Stim: decreased feeding
Lesion: increased feedling
◉ MOA: Ramelteon.
Answer: selective melatonin receptor agonist which binds to MT1
and MT2 receptors located in the suprachiasmatic nucleus
◉ What is the treatment of choice and MOA for Myesthenia Gravis.
Answer: Pyridostigmine
acetylcholinesterase inhibitor that prevents cholinesterase from
degrading ACh, thereby increasing the amount of ACh for receptor
binding
,◉ Broca's aphasia can be caused by an occlusion of which artery?.
Answer: LEFT middle cerebral artery, superior trunk
◉ Wernicke's aphasia can be caused by an occlusion of which
artery?.
Answer: Left Middle cerebral artery - inferior trunk
◉ What is the first like pharmacologic treatment for Tourettes?.
Answer: fluphenazine, pimozide, tetrabenazine - all dopamine
receptor antagonists
◉ What is Charcots triad associated with MS?.
Answer: 1. Scanning Speech
2. Intention Tremor
3. Nystagus
◉ What cells are associated with multiple sclerosis?.
Answer: Oligodendrocytes - produce myelin for the CNS.
◉ What are the characteristic MRI findings of Multiple Sclerosis?.
Answer: Periventricular lesions
, ◉ What is the first line medication for a patient presenting with
bipolar mania + first manic episode?.
Answer: LITHIUM, valproate, quetiapine, and lamotrigine.
◉ Lesion to posterior limb of internal capsule.
Answer: posterior limb of the internal capsule contains the
descending corticospinal tract and all ascending somatosensory
pathways.
Lesion leads to contralateral hemiparesis and hemianesthesia.
◉ What NT is predominantly affected in Alzheimer's disease?.
Answer: Acetylcholine
◉ Treatment of Alzheimer's Disease.
Answer: (reversible) acetylcholinesterase inhibitors
Donepezil, Galantamine, Rivastigmine, and Tacrine
Memantine (NMDA receptor antagonist) used as an adjuvant
◉ What actions occur during craniosacral flexion phase at the SBS?.
VERIFIED SOLUTIONS
◉ Hypothalamus nuclei: Dorsomedial.
Answer: stim: sham rage
lesion: decreased aggression and feeding
◉ Hypothalamus nuclei:
Anterior.
Answer: Funct: Cooling, parasympathetic (think AC =
Anterior/Cooling)
Stim: Panting or sweating
Lesion: difficulty lowering body temp
◉ Hypothalamus nuclei:
Lateral.
Answer: Funct: Hunger
,Stim: Increased feeding (ghrelin)
lesion: decreased feeding (inhibit = leptin)
◉ Hypothalamus nuclei:
Ventromedial.
Answer: Funct: Satiety
Stim: decreased feeding
Lesion: increased feedling
◉ MOA: Ramelteon.
Answer: selective melatonin receptor agonist which binds to MT1
and MT2 receptors located in the suprachiasmatic nucleus
◉ What is the treatment of choice and MOA for Myesthenia Gravis.
Answer: Pyridostigmine
acetylcholinesterase inhibitor that prevents cholinesterase from
degrading ACh, thereby increasing the amount of ACh for receptor
binding
,◉ Broca's aphasia can be caused by an occlusion of which artery?.
Answer: LEFT middle cerebral artery, superior trunk
◉ Wernicke's aphasia can be caused by an occlusion of which
artery?.
Answer: Left Middle cerebral artery - inferior trunk
◉ What is the first like pharmacologic treatment for Tourettes?.
Answer: fluphenazine, pimozide, tetrabenazine - all dopamine
receptor antagonists
◉ What is Charcots triad associated with MS?.
Answer: 1. Scanning Speech
2. Intention Tremor
3. Nystagus
◉ What cells are associated with multiple sclerosis?.
Answer: Oligodendrocytes - produce myelin for the CNS.
◉ What are the characteristic MRI findings of Multiple Sclerosis?.
Answer: Periventricular lesions
, ◉ What is the first line medication for a patient presenting with
bipolar mania + first manic episode?.
Answer: LITHIUM, valproate, quetiapine, and lamotrigine.
◉ Lesion to posterior limb of internal capsule.
Answer: posterior limb of the internal capsule contains the
descending corticospinal tract and all ascending somatosensory
pathways.
Lesion leads to contralateral hemiparesis and hemianesthesia.
◉ What NT is predominantly affected in Alzheimer's disease?.
Answer: Acetylcholine
◉ Treatment of Alzheimer's Disease.
Answer: (reversible) acetylcholinesterase inhibitors
Donepezil, Galantamine, Rivastigmine, and Tacrine
Memantine (NMDA receptor antagonist) used as an adjuvant
◉ What actions occur during craniosacral flexion phase at the SBS?.
