QUIZ 2 TEST BANK QUESTIONS NURS 5334 The University of Texas
at Arlington | UPDATED Questions with 100% Verified Answers
Question:
A 26-year-old woman with pustular psoriasis would like to
become pregnant and start a family within the next two years.
Which agent should be avoided for treatment of her psoriasis
because the duration of its teratogenic potential may affect her
plans for pregnancy? Triamcinolone acetonide Infliximab
Acitretin Calcipotriene
Answer:
Acitretin is teratogenic, and women must avoid pregnancy for
at least 3 years after the use of this drug (due to the long
duration of teratogenic potential).
Question:
Which of the following agents is used as a repigmentation
agent for patients with vitiligo that must be photoactivated by
UV radiation to form a DNA adduct inhibiting DNA
replication by psoralen plus UVA radiation? Methoxsalen
Tazarotene Hydroquinone Adapalene
Answer:
Methoxsalen: Methoxsalen is a psoralen photoactive agent
that stimulates melanocytes and is used as a repigmentation
agent for patients with vitiligo (Figure 43.7). It must be
photoactivated by UV radiation to form a DNA adduct
inhibiting DNA replication by a method called PUVA
(psoralen plus UVA radiation)
Question:
A 33-year-old man wants to quickly get his plaque psoriasis
in visible areas under control for a planned trip to Jamaica and
wants to keep it under control for at least the remainder of the
summer. Which of the following therapeutic strategies for
,psoriasis would best enable the patient to achieve his goals?
Combination therapy Step-up therapy Monotherapy
Sequential therapy
Answer:
Sequential therapy would likely be the best approach, as
stronger and sometimes more toxic agents are used initially to
rapidly clear the lesions, followed by less toxic agents for
maintenance therapy.
Question:
A 45-year-old woman burned her hand while cooking dinner.
Her skin blistered from the burn, and now the burned area is
open. Which of the following topical medications is most
appropriate to recommend to the patient for prevention of skin
infection after a burn? Retapamulin Bacitracin/polymyxin
Ozenoxacin Mupirocin
Answer:
Bacitracin/polymyxin This combination ointment containing
both bacitracin and polymyxin is mostly used for the
prevention of skin infections after burns or minor scrapes.
Question:
A 32-year-old man presents to your clinic with rosacea
characterized by erythema on his cheeks, chin, and forehead.
Which of the following topical medications would be the best
choice to treat the erythema? Ivermectin Brimonidine
Metronidazole Minocycline
Answer:
Brimonidine is an ·2 adrenoceptor agonist that reduces
erythema through vasoconstriction.
Question:
Which is correct regarding ivermectin and the treatment of
,rosacea? Reduces erythema through vasoconstriction Poorly
tolerated with the possibility of skin irritation and burning An
antiparasitic agent with unknown mechanism of action
Available as a twice a day cream
Answer:
An antiparasitic agent with unknown mechanism of action It
is an antiparasitic: Ivermectin is an antiparasitic agent and its
mechanism of action is unknown in the treatment of
papulopustular rosacea.
Question:
Which of the following is correct regarding the use of
isotretinoin in the treatment of acne? It is contraindicated in
pregnancy. It acts primarily on the corticosteroid receptors. It
is used for milder forms of acne. It is used topically in the
treatment of acne.
Answer:
Isotretinoin is an oral retinoid reserved for more severe forms
of acne. Retinoic acids play an important role in mammalian
embryogenesis. Excessive amounts of retinoids such as
isotretinoin have been shown to cause teratogenicity, but the
exact molecular mechanism is not known.
Question:
A patient has been using topical minoxidil to manage his
baldness for several years, but now wants to stop using the
medication. What is the likely consequence of discontinuing
this medication? Hair growth will be maintained. Hair color
will start to turn gray. Blood pressure will increase. Hair loss
will resume.
Answer:
, Hair loss will resume. Rationale:Topical minoxidil must be
used continuously to maintain effects on hair growth.
Minoxidil does not affect hair color, and topical minoxidil
does not affect blood pressure.
Question:
Which of the following topical anti-acne medications is the
best recommendation if one of the goals is to reduce
postinflammatory hyperpigmentation? Azelaic acid
Minocycline Clindamycin Benzoyl peroxide
Answer:
Topical azelaic acid exhibits a lightening effect on
hyperpigmented skin, which makes it useful in patients who
experience dyspigmentation as a consequence of
inflammatory acne.
Question:
A 5-year-old boy presents with impetigo lesions around his
lips. Which of the following topical agents is best to treat
these lesions caused by S. aureus? Polymyxin Mupirocin
Gentamicin Bacitracin
Answer:
Mupirocin is a topical antibiotic that works by inhibiting
protein synthesis targeting gram- positive organisms, such as
S. aureus. It is useful in treating impetigo. Gentamicin and
polymyxin target gram-negative bacteria. Bacitracin targets
gram-positive bacteria but is used for prevention of infections.
Question:
Which of the following is correct regarding trichogenic
agents? Finasteride inhibits the 5·-reductase enzyme that
controls the production of DHT from testosterone. Both oral
and topical minoxidil are commonly used for alopecia.
at Arlington | UPDATED Questions with 100% Verified Answers
Question:
A 26-year-old woman with pustular psoriasis would like to
become pregnant and start a family within the next two years.
Which agent should be avoided for treatment of her psoriasis
because the duration of its teratogenic potential may affect her
plans for pregnancy? Triamcinolone acetonide Infliximab
Acitretin Calcipotriene
Answer:
Acitretin is teratogenic, and women must avoid pregnancy for
at least 3 years after the use of this drug (due to the long
duration of teratogenic potential).
Question:
Which of the following agents is used as a repigmentation
agent for patients with vitiligo that must be photoactivated by
UV radiation to form a DNA adduct inhibiting DNA
replication by psoralen plus UVA radiation? Methoxsalen
Tazarotene Hydroquinone Adapalene
Answer:
Methoxsalen: Methoxsalen is a psoralen photoactive agent
that stimulates melanocytes and is used as a repigmentation
agent for patients with vitiligo (Figure 43.7). It must be
photoactivated by UV radiation to form a DNA adduct
inhibiting DNA replication by a method called PUVA
(psoralen plus UVA radiation)
Question:
A 33-year-old man wants to quickly get his plaque psoriasis
in visible areas under control for a planned trip to Jamaica and
wants to keep it under control for at least the remainder of the
summer. Which of the following therapeutic strategies for
,psoriasis would best enable the patient to achieve his goals?
Combination therapy Step-up therapy Monotherapy
Sequential therapy
Answer:
Sequential therapy would likely be the best approach, as
stronger and sometimes more toxic agents are used initially to
rapidly clear the lesions, followed by less toxic agents for
maintenance therapy.
Question:
A 45-year-old woman burned her hand while cooking dinner.
Her skin blistered from the burn, and now the burned area is
open. Which of the following topical medications is most
appropriate to recommend to the patient for prevention of skin
infection after a burn? Retapamulin Bacitracin/polymyxin
Ozenoxacin Mupirocin
Answer:
Bacitracin/polymyxin This combination ointment containing
both bacitracin and polymyxin is mostly used for the
prevention of skin infections after burns or minor scrapes.
Question:
A 32-year-old man presents to your clinic with rosacea
characterized by erythema on his cheeks, chin, and forehead.
Which of the following topical medications would be the best
choice to treat the erythema? Ivermectin Brimonidine
Metronidazole Minocycline
Answer:
Brimonidine is an ·2 adrenoceptor agonist that reduces
erythema through vasoconstriction.
Question:
Which is correct regarding ivermectin and the treatment of
,rosacea? Reduces erythema through vasoconstriction Poorly
tolerated with the possibility of skin irritation and burning An
antiparasitic agent with unknown mechanism of action
Available as a twice a day cream
Answer:
An antiparasitic agent with unknown mechanism of action It
is an antiparasitic: Ivermectin is an antiparasitic agent and its
mechanism of action is unknown in the treatment of
papulopustular rosacea.
Question:
Which of the following is correct regarding the use of
isotretinoin in the treatment of acne? It is contraindicated in
pregnancy. It acts primarily on the corticosteroid receptors. It
is used for milder forms of acne. It is used topically in the
treatment of acne.
Answer:
Isotretinoin is an oral retinoid reserved for more severe forms
of acne. Retinoic acids play an important role in mammalian
embryogenesis. Excessive amounts of retinoids such as
isotretinoin have been shown to cause teratogenicity, but the
exact molecular mechanism is not known.
Question:
A patient has been using topical minoxidil to manage his
baldness for several years, but now wants to stop using the
medication. What is the likely consequence of discontinuing
this medication? Hair growth will be maintained. Hair color
will start to turn gray. Blood pressure will increase. Hair loss
will resume.
Answer:
, Hair loss will resume. Rationale:Topical minoxidil must be
used continuously to maintain effects on hair growth.
Minoxidil does not affect hair color, and topical minoxidil
does not affect blood pressure.
Question:
Which of the following topical anti-acne medications is the
best recommendation if one of the goals is to reduce
postinflammatory hyperpigmentation? Azelaic acid
Minocycline Clindamycin Benzoyl peroxide
Answer:
Topical azelaic acid exhibits a lightening effect on
hyperpigmented skin, which makes it useful in patients who
experience dyspigmentation as a consequence of
inflammatory acne.
Question:
A 5-year-old boy presents with impetigo lesions around his
lips. Which of the following topical agents is best to treat
these lesions caused by S. aureus? Polymyxin Mupirocin
Gentamicin Bacitracin
Answer:
Mupirocin is a topical antibiotic that works by inhibiting
protein synthesis targeting gram- positive organisms, such as
S. aureus. It is useful in treating impetigo. Gentamicin and
polymyxin target gram-negative bacteria. Bacitracin targets
gram-positive bacteria but is used for prevention of infections.
Question:
Which of the following is correct regarding trichogenic
agents? Finasteride inhibits the 5·-reductase enzyme that
controls the production of DHT from testosterone. Both oral
and topical minoxidil are commonly used for alopecia.
