SEPSIS UROSEPSIS EXAMINATION TEST
COMPLETE QUESTIONS AND SOLUTIONS
●● T or F: Sepsis bundles improve patient outcomes
Answer: T
●● What is the new definition of sepsis?
Answer: life threatening organ dysfunction caused by dysregulated host
response to infection
●● What is included in the Sepsis Six?
Answer: 1) administer O2to maintain O2 >94%
2) take blood cultures and consider infective source
3) administer IV antibiotics
4) consider IV fluid resuscitation
5) check serial lactates
6) commence hourly urine output measurement
●● What is the definition of septic shock?
Answer: subset of sepsis with particularly profound circulatory, cellular
and metabolic abnormalities associated with a greater risk of mortality
than sepsis alone
,●● What is the diagnostic criteria for septic shock?
Answer: Vasopressor requirement required to maintain a MAP of
>65mm Hg and a serum lactate level >2mmol/L in the absence of
hypovolaemia
●● What is included in a qSOFA?
Answer: ► Respiratory rate of 22/min or greater,
► Altered mentation (Glasgow Coma Scale of <15), or
► Systolic blood pressure of 100 mm Hg or less.
●● T or F: SIRS (systematic inflammatory response syndrome) is used
as an indicator of sepsis
Answer: F
●● What is the criteria for a patient to meet SIRS?
Answer: ► Temperature >38°C or <36°C
► Respiratory rate >20 breaths per minute
► Heart rate >90 beats per minute
► White blood cell count of >12×109/L or <4×109/L
●● What are investigations to assess for end organ hypoperfusion?
Answer: ► CBC
, ► Clotting profile, with prothrombin time and INR
► Urea and electrolytes
► Liver function tests
► Serum lactate
► ABG
●● What lactate value indicated increased mortality? What does it
indicate is happening in the body?
Answer: >4 mmol/L
-hypoperfusion without hypotension due to compensation
●● What should initial fluid resuscitation be with? What should the
minimum rate be?
Answer: crystalloids
-30mL/kg of IV crystalloid fluid should be administered as a fluid
challenge within 3h
●● Why might colloid solutions not be used for sepsis?
Answer: increased risk of acute kidney injury
(more expensive, not as available)
●● What are the risks of fluid resusitation?
Answer: -prevent fluid overload
COMPLETE QUESTIONS AND SOLUTIONS
●● T or F: Sepsis bundles improve patient outcomes
Answer: T
●● What is the new definition of sepsis?
Answer: life threatening organ dysfunction caused by dysregulated host
response to infection
●● What is included in the Sepsis Six?
Answer: 1) administer O2to maintain O2 >94%
2) take blood cultures and consider infective source
3) administer IV antibiotics
4) consider IV fluid resuscitation
5) check serial lactates
6) commence hourly urine output measurement
●● What is the definition of septic shock?
Answer: subset of sepsis with particularly profound circulatory, cellular
and metabolic abnormalities associated with a greater risk of mortality
than sepsis alone
,●● What is the diagnostic criteria for septic shock?
Answer: Vasopressor requirement required to maintain a MAP of
>65mm Hg and a serum lactate level >2mmol/L in the absence of
hypovolaemia
●● What is included in a qSOFA?
Answer: ► Respiratory rate of 22/min or greater,
► Altered mentation (Glasgow Coma Scale of <15), or
► Systolic blood pressure of 100 mm Hg or less.
●● T or F: SIRS (systematic inflammatory response syndrome) is used
as an indicator of sepsis
Answer: F
●● What is the criteria for a patient to meet SIRS?
Answer: ► Temperature >38°C or <36°C
► Respiratory rate >20 breaths per minute
► Heart rate >90 beats per minute
► White blood cell count of >12×109/L or <4×109/L
●● What are investigations to assess for end organ hypoperfusion?
Answer: ► CBC
, ► Clotting profile, with prothrombin time and INR
► Urea and electrolytes
► Liver function tests
► Serum lactate
► ABG
●● What lactate value indicated increased mortality? What does it
indicate is happening in the body?
Answer: >4 mmol/L
-hypoperfusion without hypotension due to compensation
●● What should initial fluid resuscitation be with? What should the
minimum rate be?
Answer: crystalloids
-30mL/kg of IV crystalloid fluid should be administered as a fluid
challenge within 3h
●● Why might colloid solutions not be used for sepsis?
Answer: increased risk of acute kidney injury
(more expensive, not as available)
●● What are the risks of fluid resusitation?
Answer: -prevent fluid overload
