NURS 5334 The University of Texas at Arlington | UPDATED Questions
with 100% Verified Answers
Question:
Key Elements of a Prescription
Answer:
1) Prescriber Name
2) License Number
3) Contact Information
4) DEA number of prescriber and supervising physician
5) Patient Name
6) Patient DOB
7) Patient Allergies
8) Name of Medication
9) Indication for Medication
10) Strength of Medication
11) Dosing Frequency
12) Number of tablets/capsules to disepense
13) Number of refills
14) SIG or instructions for the prescription (E.g. "Take one
tablet by mouth daily")
Question:
3 primary reasons for drug monitoring
Answer:
1) determine therapeutic dosage
2) evaluating medication adequacy: desired effect achieved
3) identifying adverse effects: presence of patient harm
Question:
Pharmacokinetics
Answer:
Study of drug movement throughout the body Includes drug
metabolism and excretion Passage across cell membrane
,Question:
Absorption
Answer:
Drug's movement from site of administration to the blood
Rate=how soon effects begin Amount=how intense the effects
will be
Question:
Rate of absorption depends on
Answer:
rate of dissolution surface area blood flow lipid solubility pH
partitioning
Question:
Distribution
Answer:
Drug's movement from blood into interstitial space and then
into cells
Question:
Metabolism
Answer:
"Biotransformation" Enzyme mediated alteration of the drug
structure
Question:
Excretion
Answer:
How drugs and metabolites move out of the body
Question:
Elimination
, Answer:
combination of metabolism and excretion
Question:
Movement of drugs
Answer:
GI Tract/Site of administration-->Blood-->Liver/Kidney/Site
of action/Other Sites-- >Bile/Urine-->Outside of body
Question:
3 ways for drugs to cross cell membrane
Answer:
1) Channels and pores
2) Transport systems (P-glycoprotein)
3) Direct penetration of the membrane - *Most common*
Question:
P-Glycoprotein
Answer:
Transmembrane protein that transports a wide variety of drugs
out of cells Liver to Bile; Kidney to Urine, Placenta to
Maternal blood; Brain to Blood
Question:
Passage of drugs across membrane
Answer:
"Like dissolves like" cell membrane composition lipid - lipid
soluble drugs can cross membrane without help Must be
Non-Ionized to cross from one side to the other
Question:
Ions
with 100% Verified Answers
Question:
Key Elements of a Prescription
Answer:
1) Prescriber Name
2) License Number
3) Contact Information
4) DEA number of prescriber and supervising physician
5) Patient Name
6) Patient DOB
7) Patient Allergies
8) Name of Medication
9) Indication for Medication
10) Strength of Medication
11) Dosing Frequency
12) Number of tablets/capsules to disepense
13) Number of refills
14) SIG or instructions for the prescription (E.g. "Take one
tablet by mouth daily")
Question:
3 primary reasons for drug monitoring
Answer:
1) determine therapeutic dosage
2) evaluating medication adequacy: desired effect achieved
3) identifying adverse effects: presence of patient harm
Question:
Pharmacokinetics
Answer:
Study of drug movement throughout the body Includes drug
metabolism and excretion Passage across cell membrane
,Question:
Absorption
Answer:
Drug's movement from site of administration to the blood
Rate=how soon effects begin Amount=how intense the effects
will be
Question:
Rate of absorption depends on
Answer:
rate of dissolution surface area blood flow lipid solubility pH
partitioning
Question:
Distribution
Answer:
Drug's movement from blood into interstitial space and then
into cells
Question:
Metabolism
Answer:
"Biotransformation" Enzyme mediated alteration of the drug
structure
Question:
Excretion
Answer:
How drugs and metabolites move out of the body
Question:
Elimination
, Answer:
combination of metabolism and excretion
Question:
Movement of drugs
Answer:
GI Tract/Site of administration-->Blood-->Liver/Kidney/Site
of action/Other Sites-- >Bile/Urine-->Outside of body
Question:
3 ways for drugs to cross cell membrane
Answer:
1) Channels and pores
2) Transport systems (P-glycoprotein)
3) Direct penetration of the membrane - *Most common*
Question:
P-Glycoprotein
Answer:
Transmembrane protein that transports a wide variety of drugs
out of cells Liver to Bile; Kidney to Urine, Placenta to
Maternal blood; Brain to Blood
Question:
Passage of drugs across membrane
Answer:
"Like dissolves like" cell membrane composition lipid - lipid
soluble drugs can cross membrane without help Must be
Non-Ionized to cross from one side to the other
Question:
Ions
