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HESI A2 Biology | Questions, Answers & Study Guide | 2026/2027

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Prepare for the HESI A2 Biology exam with comprehensive practice questions, answers, and focused biology review. Covers essential concepts in cell biology, genetics, metabolism, evolution, biological organization, and human biology commonly tested on nursing and allied-health entrance exams.

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A2-Biology
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Hesi A2/Biology
Hesi A2/Biology Exam
Study online at https://quizlet.com/_h8bcom

1. Five King- Kingdom
dom Classifica- Phylum/division
tion System Class
Order
Family
Genus
Species

King Phillip Came Over For Good Soup

2. The five king- Monera, Protista, Fungi, Plantae, Animalia
doms are

3. The Mon- includes about 10,000 known species of prokaryotes such as bacteria and
era Kingdom cyanobacteria. Members of this kingdom can be unicellular organisms or
(Prokaryotes) colonies.

4. Protista Kingdom unicellular, protozoans and unicellular and multi cellular algae.

5. Fungi Kingdom eukaryotic kingdom of heterotrophic decomposers with cell walls made of chitin

6. Three Domains Bacteria, Archaea, Eukarya

7. Human Classifi- Domain: Eukarya
cation Kingdom: Animalia
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Sapiens

8. Classification system in which each species is assigned a two-part scientific name


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Hesi A2/Biology
Hesi A2/Biology Exam
Study online at https://quizlet.com/_h8bcom

binomial nomen-
clature

9. Species A group of similar organisms that can breed and produce fertile offspring.

10. Natural selection A process in which individuals that have certain inherited traits tend to survive and
reproduce at higher rates than other individuals because of those traits.

11. Darwin's Four 1. From generation to generation, there are various individuals within a species
Principles 2. Genes determine variations
3. More individuals are born than survive to maturation
4. Specific genes enable an organism to better survive

12. Gradualism The theory that evolution occurs slowly but steadily

13. punctuated equi- Pattern of evolution in which long stable periods are interrupted by brief periods
librium of more rapid change

14. stasis long periods of no change

15. scientific knowl- sum of all scientific inquiries for truths about the natural world
edge

16. scientific inquiry The diverse ways in which scientists study the natural world and propose expla-
nations based on evidence they gather.

17. Scientific Method 1. Identifying a problem or posing a question
2. Formulating a hypothesis or an educated guess
3. Conducting experiments or tests that will provide a basis to solve the problem
or answer the question.
4. Observing the results of the test
5. Drawing conclusions

18.


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Hesi A2/Biology
Hesi A2/Biology Exam
Study online at https://quizlet.com/_h8bcom

Important prop- high polarity
erties of water
hydrogen bonding

cohesiveness

adhesiveness

high specific heat

high latent heat

high heat of vaporization

19. Water is liq- room temperature
uidized at

20. high specific heat It takes a lot of energy to heat up water, which allows for a stable environment;
of water due to hydrogen bonding

21. Water is cohesive water is attracted to itself due to hydrogen bonds and it is readily attracted to
and adhesive other molecules.

22. Water is hy- If water tends to adhere to another substance
drophilic

23. Water is a good substances, particularly with polar ions and molecules, readily dissolve in water.
solvent because

24. Macromolecules A very large organic molecule composed of many smaller molecules

they play an important role in cell structure and function

25. The four basic or- 1. carbohydrates (polysaccharides)
ganic macromol- 2 .nucleic acids

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Hesi A2/Biology
Hesi A2/Biology Exam
Study online at https://quizlet.com/_h8bcom

ecules produced 3. proteins
by anabolic reac- 4.lipids
tions are

26. nucleic acids Nucleic acids are the biopolymers, or small biomolecules, essential to all known
forms of life. The term nucleic acid is the overall name for DNA and RNA. They are
composed of nucleotides, which are the monomers made of three components:
a 5-carbon sugar, a phosphate group and a nitrogenous base.

27. proteins any of a class of nitrogenous organic compounds that consist of large molecules
composed of one or more long chains of amino acids and are an essential part
of all living organisms, especially as structural components of body tissues such
as muscle, hair, collagen, etc., and as enzymes and antibodies.

28. four basic build- 1. monosaccharides (glucose)
ing blocks in- 2. amino acids
volved in catabol- 3.fatty acids (glycerol)
ic reactions 4. nucleotides

29. carbohydrates are the primary source of energy and are responsible for providing energy as
they can be easily converted to glucose. it is the oxidation of carbohydrates that
provides the cells with most of their energy.

Glucose can be further broken down by respiration or fermentation by glycolysis.

They are involved in the metabolic energy cycles of photosynthesis and respira-
tion.

Carbohydrates are made of carbon, hyrdrogen, and oxygen.

Carbohydrates are broken down into sugars or glucose.

The simple sugars can be grouped into monosaccharides and disaccharides.


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