WGU D441 Pharmacology
Study Guide–
andComprehensive
Exam Preparation.pdf
Study Guide and Exam Preparation.pdf 1 of 54
WGU D441 Pharmacology –
Comprehensive Study Guide and Exam
Preparation
Page 1 of 54 WGU
Page
D441
1 Pharmacology – Comprehensive Study Guide and Exam Preparation
,Pharmacology D441.pdf Pharmacology D441.pdf 2 of 54
Spironolactone
Diuretic - Potassium Sparing /Aldosterone Antagonist
IND- Heart failure
MOA- K-sparing, aldosterone inhibition
SE- hyperkalemia, androgen blocking, estrogen build up, ST depression
IA- other K+ sparing diuretics, lithium, NSAIDS
CI- hyperkalemia, renal failure, anuria
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Angiotensin receptor blockers (ARB'S)
ARBs
-"sartan"
Losartan, valsartan, candesartan, irbesartan
IND- htn, 2nd choice
MOA- lowers bp, inhibits/ blocks angiotensin receptors from binding. Can give w/
bradyardia, prevents systemic vasoconstriction
SE- hyperkalemia, orthostatic hypotension, angioedema
IA- monitor potassium, pregnancy, renal stenosis
CI- hyperkalemia
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Beta Blockers
Antagonist, has cholinergic effect
-"olol"
Propanolol, atenolol, esmolol, metoprolol
IND- HTN, tachy, stage fright
MOA- block adrenergic effects, lowers hr, bp & cardiac output
SE- low alertness, slow HR, cold hands & feet, tired, bronchoconstriction, bradycardia,
wheeze
IA-
CI- COPD, asthma, bradycardia, diabetic
"A-N"= 1 "O-Z"=2
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