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NURS 5315 Advanced Pathophysiology
UTA Exam 1 | Q&A 2025/2026
NURS 5315 Advanced Pathophysiology
NURS UTA
5315
Exam
Advanced
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Pathophysiology
2025_2026NURS
(1).pdf
UTA
5315
Exam
Advanced
1 _ Q&A
Pathophysiology
2025_2026 (1).pdf
UTA Exam 1 _ Q&A 2025_2026 (1).pdf
,NURS 5315 Advanced
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What can Reactive Oxygen Species cause?
Heart disease, Alzheimers, Parkinsons, Amyotrophic Lateral Sclerosis (ALS), CV disease,
HTN, HLD, DM, ischemic heart disease, HF, OSA. Lipid perioxidation, damage proteins,
fragment DNA, less protein synthesis, chromatin destruction, damage mitochondria
How are free radicals produced?
1. Normal cellular respiration
2. Absorption of extreme energy sources (radiation, UV light)
3. Metabolism of exogenous chemicals, drugs, and pesticides
4. Transition of metals
5. Nitric oxide acting like a chemical mediator and a free radical
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What is the body's defense against ROS?
Antioxidants (Vitamin E, Vitamin C, cysteine, glutathione, albumin, ceruloplasmin, transferrin)
action potential
Process of conducting an impulse. Activates the neuron --> the neuron depolarizes --> then
repolarizes
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Threshold potential
Point at which depolarization must reach in order to initiate an action potential
Hypokalemia and action potentials
HYPERpolarized (more negative, ex. -100). Less excitable. Decreased neuromuscular
excitability: weakness, smooth muscle atony, paresthesia, cardiac dysrhythmias
Hyperkalemia and action potentials
HYPOpolarized (more positive, ex: closer to 0). More excitable. Peaked T waves.
When resting membrane potential=threshold potential, it is BAD = cardiac standstill,
paresthesia, paralysis
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