NUR 378 Exam 4 Concordia University-Saint Paul | UPDATED
Questions with 100% Verified Answers
Question:
Mechanisms of action of antibiotics
Answer:
-Interference with bacterial cell wall synthesis
-Interference with protein synthesis
-Interference with replication of nucleic acids
(DNA/RNA)
-Antimetabolite action that disrupts critical
metabolic reactions inside bacterial cell
Question:
Contraindications for Sulfonamides
Answer:
-Known drug allergy to sulfonamides,
trimethoprim, Celebrex (COX-2 inhibitors)
-Pregnant women at term or nursing women
-Infants younger than 2 months
-Impaired kidney function
-Hyperkalemia (use w/ caution w/ ACE inhibitors
and angiotensin II receptor blockers)
-Megaloblastic anemia result from folic acid
deficiency
-Pharyngitis from GABHS
Question:
Adverse effects of sulfonamides
Answer:
-Sulfa allergy
-Photosensitivity
-Crystalluria
-Stevens-Johnson syndrome
,-GI upset
-Blood dyscrasias
Question:
Nursing assessment for
Sulfonamides
Answer:
-Assess for drug allergies to sulfa-type drugs
and/or sulfites (sulfonylurea, oral DM drugs,
thiazide diuretics)
-Skin assessment due to adverse effect of
Stevens-Johnson syndrome
-CBC before starting therapy (anemia concern)
-Kidney function studies: BUN, creatinine, UA
Question:
Which drugs are Macrolides?
Answer:
-Azithromycin
-Clarithromycin
-Erythromycin
Question:
Mechanism of action of Macrolides
Answer:
-Bacteriostatic drugs
-Inhibit protein synthesis by binding reversibly to
50S ribosomal subunits, preventing amino acids
from adding to peptide chain
-Inhibits transfer RNA from binding with
messenger RNA
Question:
, Therapeutic use of Macrolides
Answer:
-Upper and lower respiratory infections (mild-
moderate) casued by Haemophilus influenzae
-Streptococcus pyogenes (GABHS)
-Mycoplasma infections
-Gonorrhea/Chlamydia
-Legionnaires' disease
-Whooping cough
-Acute diptheria
Question:
Adverse effects of Macrolides
Answer:
-GI upset
-Rash
-Ototoxicity
-Dysrhythmia/Prolonged QT interval
-Decreases effectiveness of oral contraceptives
Question:
Drug interactions of Macrolides
Answer:
Drugs metabolized in the liver or protein
binding
-Carbamazepine
-Cyclosporine
-Theophylline
-Warfarin
-Oral contraceptives
Question:
Nursing assessment for Macrolides
Answer:
Questions with 100% Verified Answers
Question:
Mechanisms of action of antibiotics
Answer:
-Interference with bacterial cell wall synthesis
-Interference with protein synthesis
-Interference with replication of nucleic acids
(DNA/RNA)
-Antimetabolite action that disrupts critical
metabolic reactions inside bacterial cell
Question:
Contraindications for Sulfonamides
Answer:
-Known drug allergy to sulfonamides,
trimethoprim, Celebrex (COX-2 inhibitors)
-Pregnant women at term or nursing women
-Infants younger than 2 months
-Impaired kidney function
-Hyperkalemia (use w/ caution w/ ACE inhibitors
and angiotensin II receptor blockers)
-Megaloblastic anemia result from folic acid
deficiency
-Pharyngitis from GABHS
Question:
Adverse effects of sulfonamides
Answer:
-Sulfa allergy
-Photosensitivity
-Crystalluria
-Stevens-Johnson syndrome
,-GI upset
-Blood dyscrasias
Question:
Nursing assessment for
Sulfonamides
Answer:
-Assess for drug allergies to sulfa-type drugs
and/or sulfites (sulfonylurea, oral DM drugs,
thiazide diuretics)
-Skin assessment due to adverse effect of
Stevens-Johnson syndrome
-CBC before starting therapy (anemia concern)
-Kidney function studies: BUN, creatinine, UA
Question:
Which drugs are Macrolides?
Answer:
-Azithromycin
-Clarithromycin
-Erythromycin
Question:
Mechanism of action of Macrolides
Answer:
-Bacteriostatic drugs
-Inhibit protein synthesis by binding reversibly to
50S ribosomal subunits, preventing amino acids
from adding to peptide chain
-Inhibits transfer RNA from binding with
messenger RNA
Question:
, Therapeutic use of Macrolides
Answer:
-Upper and lower respiratory infections (mild-
moderate) casued by Haemophilus influenzae
-Streptococcus pyogenes (GABHS)
-Mycoplasma infections
-Gonorrhea/Chlamydia
-Legionnaires' disease
-Whooping cough
-Acute diptheria
Question:
Adverse effects of Macrolides
Answer:
-GI upset
-Rash
-Ototoxicity
-Dysrhythmia/Prolonged QT interval
-Decreases effectiveness of oral contraceptives
Question:
Drug interactions of Macrolides
Answer:
Drugs metabolized in the liver or protein
binding
-Carbamazepine
-Cyclosporine
-Theophylline
-Warfarin
-Oral contraceptives
Question:
Nursing assessment for Macrolides
Answer:
