Test Bank - Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition (Frandsen, 2026), 9781975222321, Chapter 1-61 All Chapters

ABRAM’S CLINICAL DRUG THERAPY RATIONALES FOR
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NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
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jl TESTBANK/COMPLETE GUIDE 2026-2027/ALL CHAPTERS 1-61
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,Chapter 1: The Foundation of Pharmacology: Quality and Safety
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1. Apatientdiagnosed with obsessive–compulsive disorder has been prescribed
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oralparoxetine hydrochloride. What is the expected effect for this prescription?
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A. Curativeeffect on symptoms jl jl jl



B. Systemiceffect onsymptoms jl jl jl



C. Localeffect on symptoms jl jl jl



D. Parenteraleffect on symptoms jl jl jl




ACCURATE ANSWER:-B jl



REASONING:->>>Pharmaceutical drug that produce systemic effects are taken into the jl jl jl jl jl jl jl jl jl



body, circulated through the bloodstream to their sites of action in various body tissues, and
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eventually eliminated from the body. Curative agents are given to cure a disease process.
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Inthis case, paroxetine hydrochloride will control the symptoms but not curethe disorder.
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Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act mainly at jl jl jl jl jl jl jl jl jl jl jl jl jl



the site of application. Paroxetine hydrochloride is not administered parenterally. Parenteral
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agentsare administered subcutaneously, intramuscularly, or intravenously.
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POINTS: 1 REFERENCE: p. 3, Introduction jl jl OBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
jl Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process j l jl jl jl



BLM: Cognitive Level: Understand NOT: Multiple Choice
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2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug is a
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naturally occurring substance that has been cheG
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name for this type of pharmaceutical drug?
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A. Synthetic drug jl



B. Semisynthetic drug jl



C. Biotechnology drug jl



D. Prototypedrug jl




ACCURATE ANSWER:-B jl



REASONING:->>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are jl jl jl jl jl jl



naturally occurring substances that have been chemically modified. Synthetic
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pharmaceutical drug are more standardized in their chemical characteristics, more
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consistent in their effects, and less likely to produce allergic reactions. Biotechnology
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pharmaceutical drug involve manipulating DNAand RNA and recombining genes into
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hybrid molecules that can be inserted into living organisms. Prototype pharmaceutical drug
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are the first drug of a particular group to be developed.
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POINTS: 1 REFERENCE: p. 3, Drug Sources jl jl jl OBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
jl Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process j l jl jl jl



BLM: Cognitive Level: Understand NOT: Multiple Choice
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3. Whichclassification applies to morphine? jl jl jl jl



A. Centralnervous systemdepressant jl jl jl



B. Centralnervous system stimulant jl jl jl

, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A jl



REASONING:->>>Pharmaceutical drug are classified according to their effects on jl jl jl jl jl jl jl jl



particular body systems, their therapeutic uses, and their chemical characteristics. Morphine
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is classified as a central nervous system depressant and will produce this effect in the hospital
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client. Acentral nervous system stimulant increases attention and raises mood. An anti-
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inflammatoryagent decreases inflammation at the site of tissue or joint inflammation. An jl jl jl jl jl jl jl jl jl jl jl jl



antihypertensiveagent reduces blood pressure.
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POINTS: 1 REFERENCE: p. 3, Drug jl jl



Classifications and PrototypesOBJ: 1
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NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
jl Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember j l NOT: Multiple Choice jl jl j l jl




4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical drug
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belongs to whichdrug group?
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A. Selective serotonin reuptake inhibitors jl jl jl



B. Diuretics
C. Penicillins
D. ACE inhibitors jl




ACCURATE ANSWER:-C jl



REASONING:->>>The generic name often indicates the drug group (e.g., pharmaceutical drug
GRADESBOOST.CO
with generic names ending in ―cillin‖ are penicillins). Selective serotonin
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reuptakeinhibitors are pharmaceutical drugs
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that have antidepressant effects; SSRI is a broad classification, not a generic name. Diureticsare
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pharmaceutical drugs that increase urine output; diuretic is a broad classification, not a
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generic name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
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not thegeneric name.
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POINTS: 1 REFERENCE: p. 3, Drug Names jl jl jl OBJ: 2
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
jl Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand NOT: Multiple Choice
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5. The administration ofdiphenhydramine is regulated bywhich U.S. government agency?
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A. PublicHealthService jl jl



B. Federal Trade Commission jl jl



C. Occupational Safetyand Health Administration jl jl jl jl



D. Food and jl




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on

ACCURATE ANSWER:-D jl

, REASONING:->>>The Food and Drug Administration approves pharmaceutical drug for jl jl jl jl jl jl jl jl



over- the-counter availability, including the transfer of pharmaceutical drug from
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prescription to OTC status, and may require clinical trials to determine the safety and
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effectiveness of OTC use.The Public Health Service is regulated by the state to maintain the
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health of individual citizens of the state. The Federal Trade Commission regulates imports
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and exports throughout the nation. TheOccupational Safetyand Health Administration
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regulates safetywithin the workplace.
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POINTS: 1 REFERENCE: p. 4, Prescriptionand Nonprescription jl jl jl jl



Pharmaceutical drug OBJ: 4 jl jl



NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
jl Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand j l NOT: Multiple Choice jl jl j l jl




6. In the U.S., the administration of anabolic steroids is regulated bywhich law?
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A. TheFood, Drug, and Cosmetic Act of 1938 jl jl jl jl jl jl jl



B. The Comprehensive Drug Abuse Prevention and Control Act
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C. TheHarrison Narcotic Act jl jl jl



D. The SherleyAmendment jl jl




ACCURATE ANSWER:-B jl



REASONING:->>>The Comprehensive Drug Abuse Prevention and Control Act regulates jl jl jl jl jl jl jl jl



the manufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and
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anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA
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powers and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic
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Act restricted the importation, manufacture, sale, and use ofopium,cocaine, marijuana, and
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other pharmaceuticaldrugthat the act defi GneRd AaDs E
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tiO
csS
.TTh.eCSOhM
erley Amendment of1912 jl jl jl jl jl jl jl jl jl j l jl jl jl jl



prohibited fraudulent claims of drug effectiveness.
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POINTS: 1 REFERENCE: p. 4, Prescriptionand Nonprescription jl jl jl jl



Pharmaceutical drug OBJ: 3 jl jl



NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
jl Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember j l NOT: Multiple Choice jl jl j l jl




7. A nursing attendant is responsible for maintaining an accurate count and record of the
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controlled substances on the nursing division. This nursing action is regulated bywhich
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U.S. law or agency? jl jl jl



A. TheFood, Drug, and Cosmetic Act of 1938 jl jl jl jl jl jl jl



B. ThePublic Health Service jl jl jl



C. The Drug Enforcement Administration jl jl jl



D. TheSherley jl




AmendmentACCURATE
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jl ANSWER:-C