[STUDY GUIDE] • HIGH-YIELD PRACTICE & REVIEW EDITION
COMSAE 113 Level 2 Questions &
Answers 2026/2027 | Latest High-Yield
Review
Comprehensive Examination Question Bank • Concept Mapping
TOTAL QUESTIONS EXAM TOPICS RATIONALES
146 Questions 12 Modules 100% Verified
DOCUMENT OVERVIEW
This document contains 146 verified questions with correct answers provided, focusing on high-yield nursing
concepts. Each question is designed to reinforce understanding of clinical scenarios and medical knowledge
applicable to nursing practice, making it suitable for NCLEX preparation, course review, and certification exam
study.
EXAM BLUEPRINT & TOPIC DISTRIBUTION
Systematic breakdown of subject domains and exam coverage.
Topic Module Scope & Core Focus Questions Share (%)
Focuses on conditions related to hormonal imbalances and
Endocrine Disorders their management. 13 Qs 8.9%
Covers various infectious diseases, their presentations, and
Infectious Diseases treatment options. 13 Qs 8.9%
Examines neurological disorders and their clinical
Neurological Conditions manifestations. 12 Qs 8.2%
Addresses diseases related to the cardiovascular system and
Cardiovascular Issues their implications. 12 Qs 8.2%
Explores various pulmonary diseases and their management
Respiratory Conditions strategies. 12 Qs 8.2%
Focuses on gastrointestinal conditions and their treatment
Gastrointestinal Disorders approaches. 12 Qs 8.2%
Confidential • Student Study Edition • Practice & Review Guide Page 1 of 34
,STUDENT STUDY & MASTERY EDITION PRACTICE & REVIEW GUIDE
Covers blood-related conditions and their clinical
Hematologic Disorders management. 12 Qs 8.2%
Examines mental health disorders and relevant therapeutic
Psychiatric Conditions interventions. 12 Qs 8.2%
Musculoskeletal Disorders Focuses on conditions affecting the musculoskeletal system. 12 Qs 8.2%
Covers issues related to reproductive health and pertinent
Reproductive Health clinical considerations. 12 Qs 8.2%
Explores study designs and statistical concepts relevant to
Research Methodology healthcare research. 12 Qs 8.2%
Focuses on healthcare issues specific to pediatric
Pediatric Considerations populations. 12 Qs 8.2%
Total Exam Coverage 12 Integrated Topic Modules 146 Qs 100.0%
Confidential • Student Study Edition • Practice & Review Guide Page 2 of 34
,STUDENT STUDY & MASTERY EDITION PRACTICE & REVIEW GUIDE
TOPIC 1: ENDOCRINE DISORDERS
13 Questions • 8.9% of Exam • Focuses on conditions related to hormonal imbalances and their management.
QUESTION 1
Classic Presentation of Myxedema Coma:
Answer: The most severe form of hypothyroidism.
The classic presentation is
- altered mental status/coma
- hypothermia
- bradycardia, hypoventilation
- dry coarse skin
- nonpitting edema (myxedema)
- delayed relaxation of deep tendon reflexes.
Elderly patients are particularly susceptible, and a precipitating event (infection, medication change, MI, cold
exposure) is often present.
QUESTION 2
How to confirm myxedema coma diagnosis?
Answer: Free thyroxine.
Tx: IV levothyroxine and empiric glucocorticoids should begin immediately.
QUESTION 3
FPR treatment position:
Answer: Neutral compress, EASE.
QUESTION 4
Which drug is an alkylating chemotherapy agent that has historically been used for
severe refractory autoimmune disease?
Answer: Chlorambucil.
Confidential • Student Study Edition • Practice & Review Guide Page 3 of 34
, STUDENT STUDY & MASTERY EDITION PRACTICE & REVIEW GUIDE
QUESTION 5
Atypical pneumonia pathogens (Mycoplasma, Chlamydia, Legionella) are treated with?
Answer: Macrolides, doxycycline, or fluoroquinolones.
QUESTION 6
Perimenopause =
Answer: Irregular menses, vasomotor symptoms.
QUESTION 7
When a lung mass is discovered, the next step is to obtain a
Answer: Tissue diagnosis. via biopsy.
QUESTION 8
Trichomonas → on wet mount?
Answer: Motile flagellated organisms on wet mount.
QUESTION 9
Hypothermia (35.5 °C)
Bradycardia (58/min)
Weight gain
Memory loss, fatigue
Hypoactive bowel sounds (constipation)
Dry skin
Answer: Primary Hypothyroidism.
Confidential • Student Study Edition • Practice & Review Guide Page 4 of 34
COMSAE 113 Level 2 Questions &
Answers 2026/2027 | Latest High-Yield
Review
Comprehensive Examination Question Bank • Concept Mapping
TOTAL QUESTIONS EXAM TOPICS RATIONALES
146 Questions 12 Modules 100% Verified
DOCUMENT OVERVIEW
This document contains 146 verified questions with correct answers provided, focusing on high-yield nursing
concepts. Each question is designed to reinforce understanding of clinical scenarios and medical knowledge
applicable to nursing practice, making it suitable for NCLEX preparation, course review, and certification exam
study.
EXAM BLUEPRINT & TOPIC DISTRIBUTION
Systematic breakdown of subject domains and exam coverage.
Topic Module Scope & Core Focus Questions Share (%)
Focuses on conditions related to hormonal imbalances and
Endocrine Disorders their management. 13 Qs 8.9%
Covers various infectious diseases, their presentations, and
Infectious Diseases treatment options. 13 Qs 8.9%
Examines neurological disorders and their clinical
Neurological Conditions manifestations. 12 Qs 8.2%
Addresses diseases related to the cardiovascular system and
Cardiovascular Issues their implications. 12 Qs 8.2%
Explores various pulmonary diseases and their management
Respiratory Conditions strategies. 12 Qs 8.2%
Focuses on gastrointestinal conditions and their treatment
Gastrointestinal Disorders approaches. 12 Qs 8.2%
Confidential • Student Study Edition • Practice & Review Guide Page 1 of 34
,STUDENT STUDY & MASTERY EDITION PRACTICE & REVIEW GUIDE
Covers blood-related conditions and their clinical
Hematologic Disorders management. 12 Qs 8.2%
Examines mental health disorders and relevant therapeutic
Psychiatric Conditions interventions. 12 Qs 8.2%
Musculoskeletal Disorders Focuses on conditions affecting the musculoskeletal system. 12 Qs 8.2%
Covers issues related to reproductive health and pertinent
Reproductive Health clinical considerations. 12 Qs 8.2%
Explores study designs and statistical concepts relevant to
Research Methodology healthcare research. 12 Qs 8.2%
Focuses on healthcare issues specific to pediatric
Pediatric Considerations populations. 12 Qs 8.2%
Total Exam Coverage 12 Integrated Topic Modules 146 Qs 100.0%
Confidential • Student Study Edition • Practice & Review Guide Page 2 of 34
,STUDENT STUDY & MASTERY EDITION PRACTICE & REVIEW GUIDE
TOPIC 1: ENDOCRINE DISORDERS
13 Questions • 8.9% of Exam • Focuses on conditions related to hormonal imbalances and their management.
QUESTION 1
Classic Presentation of Myxedema Coma:
Answer: The most severe form of hypothyroidism.
The classic presentation is
- altered mental status/coma
- hypothermia
- bradycardia, hypoventilation
- dry coarse skin
- nonpitting edema (myxedema)
- delayed relaxation of deep tendon reflexes.
Elderly patients are particularly susceptible, and a precipitating event (infection, medication change, MI, cold
exposure) is often present.
QUESTION 2
How to confirm myxedema coma diagnosis?
Answer: Free thyroxine.
Tx: IV levothyroxine and empiric glucocorticoids should begin immediately.
QUESTION 3
FPR treatment position:
Answer: Neutral compress, EASE.
QUESTION 4
Which drug is an alkylating chemotherapy agent that has historically been used for
severe refractory autoimmune disease?
Answer: Chlorambucil.
Confidential • Student Study Edition • Practice & Review Guide Page 3 of 34
, STUDENT STUDY & MASTERY EDITION PRACTICE & REVIEW GUIDE
QUESTION 5
Atypical pneumonia pathogens (Mycoplasma, Chlamydia, Legionella) are treated with?
Answer: Macrolides, doxycycline, or fluoroquinolones.
QUESTION 6
Perimenopause =
Answer: Irregular menses, vasomotor symptoms.
QUESTION 7
When a lung mass is discovered, the next step is to obtain a
Answer: Tissue diagnosis. via biopsy.
QUESTION 8
Trichomonas → on wet mount?
Answer: Motile flagellated organisms on wet mount.
QUESTION 9
Hypothermia (35.5 °C)
Bradycardia (58/min)
Weight gain
Memory loss, fatigue
Hypoactive bowel sounds (constipation)
Dry skin
Answer: Primary Hypothyroidism.
Confidential • Student Study Edition • Practice & Review Guide Page 4 of 34
