MSN 570 Advanced
Pathophysiology
2026/2027 – Questions,
Answers & Complete
Study Guide
MI - answers 100% correct✔✔ Death of
myocardium from sudden blockage of coronary
artery blood flow
What causes cell death in MI? - answers 100%
correct✔✔ unstable plaque breaks off, triggering
platelet aggregation, coagulation cascade and
,thrombus formation. continued no blood flow in 10
seconds ischemia, 20 minutes cell die
What consequence of cell death leads to CP? -
answers 100% correct✔✔ hypoxia as cannot
meet cell demand for oxygen
How is MI diagnosed - answers 100% correct✔✔
EKG (STEMI) or elevated Troponin (non-STEMI)
What might you find in blood consistent with MI? -
answers 100% correct✔✔ elevated CK MB,
Troponin
Where does CK MB and Troponin come from? -
answers 100% correct✔✔ Release of lysosomal
enzymes; CK MB detected after myocardial
necrosis, Troponin released from damaged heart
muscle
3 mechanism of cell injury related to reperfussion
injury - answers 100% correct✔✔ ischemia,
necrosis, reperfussion l/t RAS
, define reperfussion injury - answers 100%
correct✔✔ injury that occurs after oxygen is
reintroduced to tissue perfusion
how does inflammatory process contribute to
reperfussion injury? - answers 100% correct✔✔
as oxygen is reintroduced it comes in contact with
damaged proteins triggering inflammatory response
how does oxidative process contribute to RI? -
answers 100% correct✔✔ RAS causes
impairment of cell membrane and pro-apotptoic cells
release. making cell unstable
what is primary Hypertension? - answers 100%
correct✔✔ Essential or idiopathic, elevated BP
without an identified cause, accounts for 90 - 95% of
all cases of hypertension?
what is secondary hypertension? - answers 100%
correct✔✔ Elevated BP, labile BP; related to
conditions ie kidney dz; resistant to BP meds
Pathophysiology
2026/2027 – Questions,
Answers & Complete
Study Guide
MI - answers 100% correct✔✔ Death of
myocardium from sudden blockage of coronary
artery blood flow
What causes cell death in MI? - answers 100%
correct✔✔ unstable plaque breaks off, triggering
platelet aggregation, coagulation cascade and
,thrombus formation. continued no blood flow in 10
seconds ischemia, 20 minutes cell die
What consequence of cell death leads to CP? -
answers 100% correct✔✔ hypoxia as cannot
meet cell demand for oxygen
How is MI diagnosed - answers 100% correct✔✔
EKG (STEMI) or elevated Troponin (non-STEMI)
What might you find in blood consistent with MI? -
answers 100% correct✔✔ elevated CK MB,
Troponin
Where does CK MB and Troponin come from? -
answers 100% correct✔✔ Release of lysosomal
enzymes; CK MB detected after myocardial
necrosis, Troponin released from damaged heart
muscle
3 mechanism of cell injury related to reperfussion
injury - answers 100% correct✔✔ ischemia,
necrosis, reperfussion l/t RAS
, define reperfussion injury - answers 100%
correct✔✔ injury that occurs after oxygen is
reintroduced to tissue perfusion
how does inflammatory process contribute to
reperfussion injury? - answers 100% correct✔✔
as oxygen is reintroduced it comes in contact with
damaged proteins triggering inflammatory response
how does oxidative process contribute to RI? -
answers 100% correct✔✔ RAS causes
impairment of cell membrane and pro-apotptoic cells
release. making cell unstable
what is primary Hypertension? - answers 100%
correct✔✔ Essential or idiopathic, elevated BP
without an identified cause, accounts for 90 - 95% of
all cases of hypertension?
what is secondary hypertension? - answers 100%
correct✔✔ Elevated BP, labile BP; related to
conditions ie kidney dz; resistant to BP meds
