NUR 621 (Adult_Gero Acute) MOD #10 (heme_onc) Questions with CORRECT Answers (Grade A+)

NUR 621 (Adult_Gero Acute) MOD #10 (heme_onc) Questions with CORRECT Answers (Grade
A+)


Question 1:

hemophilia A vs hemophilia B

Answer:

hemophilia A (defects in factor VIII hemophilia B (defects in factor IX)

-both x linked recessive

-both primarily in males

Question 2:

defect in synthesis of Von Willebrand factor

-MOST COMMON INHERITED BLEEDING DIS-

ORDER

-affects males and females

-works by facilitating platelet adhesions and

transporting factor VIII

Answer:

Von Willebrand disease

Question 3:

s/s hemophilia A/B, VW

Answer:

-excessive bleeding/bruising

-severe bleeding after minor trauma

-hemarthroses/painful joints

-epistaxis

-prolonged menses

-hematuria

Question 4:

, treatment hemophilia A

Answer:

-factor VIII (within one hour of bleeding)

-DDAVP

-prophylaxis factor VIII infusions (severe)

Question 5:

treatment Hemophilia B

Answer:

-factor IX (within one hour of bleeding)

Question 6:

treatment VW disease

Answer:

-WF factor replacement

-DDAVP

-topical thrombin for superficial cuts

-aminocaproic acid or TXA -drugs that

prevent fibrinolysis (TXA is 6X stronger than aminocaproic acid)

Question 7:

why doesn't Vit K work for hemophilia/VW?

Answer:

it is on extrinsic pathway, factors 8,9 are intrinsic

Question 8:

What is the most appropriate initial treatment of mild mucosal bleeding in a patient with VW

disease?

Answer:
DDAVP