NUR 621 (Adult_Gero Acute) MOD #5, Part 2 (PAH, liability) Questions with CORRECT Answers
(Grade A+)
Question 1:
elevated pulmonary artery pressure due to narrowed lumens
-can be from right/left sided HF, mitral valve
stenosis, PE, drugs, infections, autoimmune disease, polycythemia vera
Answer:
pulmonary arterial hypertension (PAH)
Question 2:
if PAH is not treated, it can be
Answer:
fatalcan lead to right sided heart failure
Question 3:
complication of untreated congenital heart defects, like ASD/VSD/PDA, can cause high pressure in
the pulmonary arteries
-causes vasoconstriction, fibrosis, vascular remodeling
Answer:
Eisenmenger syndrome
Question 4:
what happens during idiopathic PAH?
Answer:
endothelial damage
-smooth muscle hypertrophy
-cytokine mediated inflammation
Question 5:
heritable PAH is
Answer:
, autosomal dominant, seen more in females
-BMPR2 mutation
Question 6:
examples of drugs/toxins that can cause PAH
Answer:
SSRI's, Adderall, cocaine, meth
Question 7:
parasitic infection that can cause PAH, has a better prognosis than idiopathic PAH
-found tropical locations
Answer:
Schistosomiasis
Question 8:
25% of PAH cases, causes by SLE, RA, connective tissue disease, systemic sclerosis
Answer:
autoimmune mediated vascular injury PAH
Question 9:
PAH is also associated with
Answer:
HIV and portal hypertension (causes increased pressure and backflow to right heart)
Question 10:
dyspnea on exertion to dyspnea rest
- angina, hemoptysis, edema, palpitations are
all signs of
Answer:
PAH
Question 11:
loud S2, parasternal lift, tachypnea, s4 are
(Grade A+)
Question 1:
elevated pulmonary artery pressure due to narrowed lumens
-can be from right/left sided HF, mitral valve
stenosis, PE, drugs, infections, autoimmune disease, polycythemia vera
Answer:
pulmonary arterial hypertension (PAH)
Question 2:
if PAH is not treated, it can be
Answer:
fatalcan lead to right sided heart failure
Question 3:
complication of untreated congenital heart defects, like ASD/VSD/PDA, can cause high pressure in
the pulmonary arteries
-causes vasoconstriction, fibrosis, vascular remodeling
Answer:
Eisenmenger syndrome
Question 4:
what happens during idiopathic PAH?
Answer:
endothelial damage
-smooth muscle hypertrophy
-cytokine mediated inflammation
Question 5:
heritable PAH is
Answer:
, autosomal dominant, seen more in females
-BMPR2 mutation
Question 6:
examples of drugs/toxins that can cause PAH
Answer:
SSRI's, Adderall, cocaine, meth
Question 7:
parasitic infection that can cause PAH, has a better prognosis than idiopathic PAH
-found tropical locations
Answer:
Schistosomiasis
Question 8:
25% of PAH cases, causes by SLE, RA, connective tissue disease, systemic sclerosis
Answer:
autoimmune mediated vascular injury PAH
Question 9:
PAH is also associated with
Answer:
HIV and portal hypertension (causes increased pressure and backflow to right heart)
Question 10:
dyspnea on exertion to dyspnea rest
- angina, hemoptysis, edema, palpitations are
all signs of
Answer:
PAH
Question 11:
loud S2, parasternal lift, tachypnea, s4 are