NR 565 ADVANCED PHARMACOLOGY
EXAM 2 PRACTICE (VERIFIED AND
CORRECT Q & A) SATISFACTION
GUARANTEED 2026/2027
CHAMBERLAIN
1. A patient taking an ACE inhibitor for hypertension develops a persistent, dry cough. Which
mediator is primarily responsible for this adverse effect?
A. Angiotensin II
B. Bradykinin
C. Aldosterone
D. Renin
Answer: B
Conceptual Explanation: ACE inhibitors prevent the breakdown of bradykinin, leading to
its accumulation in the lungs, which triggers the characteristic dry cough.
2. When initiating statin therapy, which laboratory value must be assessed at baseline and
then only if clinically indicated for muscle symptoms?
A. Prothrombin time
B. Serum albumin
,C. Creatinine kinase (CK)
D. Hemoglobin A1c
Answer: C
Conceptual Explanation: Baseline CK is recommended for patients at risk for myopathy;
routine monitoring isn’t required unless the patient reports muscle pain or weakness.
3. A patient with atrial fibrillation is prescribed Warfarin. What is the target International
Normalized Ratio (INR) for this patient?
A. 1.0 to 2.0
B. 2.0 to 3.0
C. 3.0 to 4.0
D. 1.5 to 2.5
Answer: B
Conceptual Explanation: For most indications including atrial fibrillation, the standard
therapeutic range for INR is 2.0 to 3.0.
4. Which class of antihypertensives is contraindicated in a patient with a known history of
severe asthma due to the risk of bronchospasm?
A. Calcium Channel Blockers
B. Non-selective Beta-blockers
C. Thiazide Diuretics
, D. ARBs
Answer: B
Conceptual Explanation: Non-selective beta-blockers (like Propranolol) block Beta-2
receptors in the lungs, potentially causing bronchoconstriction in asthmatic patients.
5. Digoxin toxicity is significantly potentiated by which electrolyte imbalance?
A. Hyperkalemia
B. Hypokalemia
C. Hyponatremia
D. Hypernatremia
Answer: B
Conceptual Explanation: Hypokalemia increases the risk of digoxin toxicity because
potassium and digoxin compete for binding sites on the Na+/K+ ATPase pump.
6. Amiodarone has a very long half-life and several toxicities. Which organ system is most
critically affected by chronic pulmonary fibrosis associated with this drug?
A. Renal system
B. Hepatic system
C. Respiratory system
D. Endocrine system
EXAM 2 PRACTICE (VERIFIED AND
CORRECT Q & A) SATISFACTION
GUARANTEED 2026/2027
CHAMBERLAIN
1. A patient taking an ACE inhibitor for hypertension develops a persistent, dry cough. Which
mediator is primarily responsible for this adverse effect?
A. Angiotensin II
B. Bradykinin
C. Aldosterone
D. Renin
Answer: B
Conceptual Explanation: ACE inhibitors prevent the breakdown of bradykinin, leading to
its accumulation in the lungs, which triggers the characteristic dry cough.
2. When initiating statin therapy, which laboratory value must be assessed at baseline and
then only if clinically indicated for muscle symptoms?
A. Prothrombin time
B. Serum albumin
,C. Creatinine kinase (CK)
D. Hemoglobin A1c
Answer: C
Conceptual Explanation: Baseline CK is recommended for patients at risk for myopathy;
routine monitoring isn’t required unless the patient reports muscle pain or weakness.
3. A patient with atrial fibrillation is prescribed Warfarin. What is the target International
Normalized Ratio (INR) for this patient?
A. 1.0 to 2.0
B. 2.0 to 3.0
C. 3.0 to 4.0
D. 1.5 to 2.5
Answer: B
Conceptual Explanation: For most indications including atrial fibrillation, the standard
therapeutic range for INR is 2.0 to 3.0.
4. Which class of antihypertensives is contraindicated in a patient with a known history of
severe asthma due to the risk of bronchospasm?
A. Calcium Channel Blockers
B. Non-selective Beta-blockers
C. Thiazide Diuretics
, D. ARBs
Answer: B
Conceptual Explanation: Non-selective beta-blockers (like Propranolol) block Beta-2
receptors in the lungs, potentially causing bronchoconstriction in asthmatic patients.
5. Digoxin toxicity is significantly potentiated by which electrolyte imbalance?
A. Hyperkalemia
B. Hypokalemia
C. Hyponatremia
D. Hypernatremia
Answer: B
Conceptual Explanation: Hypokalemia increases the risk of digoxin toxicity because
potassium and digoxin compete for binding sites on the Na+/K+ ATPase pump.
6. Amiodarone has a very long half-life and several toxicities. Which organ system is most
critically affected by chronic pulmonary fibrosis associated with this drug?
A. Renal system
B. Hepatic system
C. Respiratory system
D. Endocrine system
