NSG5003. QUIZ 2 REVIEW: KEY CONCEPTS IN HEMATOLOGY AND
IMMUNOLOGY QUESTIONS WITH COMPLETE SOLUTIONS
1. Malignant tumors, compared with benign tumors, have more rapid growth rat vg vg vg vg vg vg vg vg vg vg
es, specific microscopic alterations, absence of normal tissue organization and
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no capsule. They invade blood vessels and lymphatics and have distant metasta
vg vg vg vg vg vg vg vg vg vg vg
ses. Several of the hallmarks of these cancers include sustained proliferation si
vg vg vg vg vg vg vg vg vg vg vg
gnaling, evading growth suppression and replication. immortality. Metastasis i vg vg vg vg vg vg vg vg
s the major cause of death from cancer. Metastasis is a complex process that req
vg vg vg vg vg vg vg vg vg vg vg vg vg vg
uires cells to have many new abilities, including the ability to invade. survive a
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nd proliferate in a new environment.
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2. Acute lymphoid leukemia (ALL) is primarily diagnosed in pediatric pa
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tients.
3. B12 Deficiency Anemia B12 deficiency anemia occurs when there is a lack of t
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he vitamin B12 in the body, which leads to a decrease in the production of healt
vg vg vg vg vg vg vg vg vg vg vg vg vg vg vg
hy red blood cells. Symptoms of B12 deficiency can vary from person to person
vg vg vg vg vg vg vg vg vg vg vg vg vg
, but there is some common signs and symptoms to look for.
vg vg vg vg vg vg vg vg vg vg vg
1.fatigue and weakness 2. Pale or yellowish skin. 3. Shortness of breath. 4. Dizzi vg vg vg vg vg vg vg vg vg vg vg vg vg
ness or Lightheadedness 5 Tingling or numbness. 6 Inflamed tongue. 7. changes
vg vg vg vg vg vg vg vg vg vg vg vg
in mental health vg vg
4. Iron deficiency anemia red blood cells are microcytic and hypochromic.
vg vg vg vg vg vg vg vg vg
5. Chronic Myeloid Leukemia (CML) is a type of cancer that affects the bone vg vg vg vg vg vg vg vg vg vg vg vg vg
marrow and blood cells. CML is primarily caused by genetic mutation known vg vg vg vg vg vg vg vg vg vg vg vg
as the Philadelphia chromosome. This mutation occurs when two specific gene
vg vg vg vg vg vg vg vg vg vg
s, the BCR which is the break point cluster region gene and the ABL1 Gene fuse
vg vg vg vg vg vg vg vg vg vg vg vg vg vg vg
d together. The presence of the Philadelphia chromosome leads to the producti
vg vg vg vg vg vg vg vg vg vg vg
on of an abnormal protein called BCR-
vg vg vg vg vg vg
ABL1 which then triggers the overgrowth of white blood cells in the bone marr
vg vg vg vg vg vg vg vg vg vg vg vg vg
ow.
6. Types of immunity. Innate immunity is the body's first line of defense and is p
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resent at birth. It simply provides a generalized, nonspecific response to a wide r
vg vg vg vg vg vg vg vg vg vg vg vg vg
ange or pathogen. In it, immunity includes physical barriers like the skin and m
vg vg vg vg vg vg vg vg vg vg vg vg vg
ucous membranes. Adaptive immunity. Adaptive immunity is also known as
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acquired. Immunity develops over time in response to exposure to specific path vg vg vg vg vg vg vg vg vg vg vg
ogens. It is highly specific and provides a targeted response to the particular pat
vg vg vg vg vg vg vg vg vg vg vg vg vg
hogen that is encountered. Passive immunity. Passive immunity is temporary
vg vg vg v g vg vg vg vg vg vg
and is acquired through another source rather than the body's own. System. As st
vg vg vg vg vg vg vg vg vg vg vg vg vg
, ated, it only provides short-
vg vg vg vg
term protection. It can be acquired naturally, such as the transfer of antibodies
vg vg vg vg vg vg vg vg vg vg vg vg
IMMUNOLOGY QUESTIONS WITH COMPLETE SOLUTIONS
1. Malignant tumors, compared with benign tumors, have more rapid growth rat vg vg vg vg vg vg vg vg vg vg
es, specific microscopic alterations, absence of normal tissue organization and
vg vg vg vg vg vg vg vg vg vg
no capsule. They invade blood vessels and lymphatics and have distant metasta
vg vg vg vg vg vg vg vg vg vg vg
ses. Several of the hallmarks of these cancers include sustained proliferation si
vg vg vg vg vg vg vg vg vg vg vg
gnaling, evading growth suppression and replication. immortality. Metastasis i vg vg vg vg vg vg vg vg
s the major cause of death from cancer. Metastasis is a complex process that req
vg vg vg vg vg vg vg vg vg vg vg vg vg vg
uires cells to have many new abilities, including the ability to invade. survive a
vg vg vg vg vg vg v g vg vg vg vg vg vg
nd proliferate in a new environment.
vg vg vg vg vg
2. Acute lymphoid leukemia (ALL) is primarily diagnosed in pediatric pa
vg vg vg vg vg vg vg vg vg
tients.
3. B12 Deficiency Anemia B12 deficiency anemia occurs when there is a lack of t
vg vg vg vg vg vg vg vg vg vg vg vg vg
he vitamin B12 in the body, which leads to a decrease in the production of healt
vg vg vg vg vg vg vg vg vg vg vg vg vg vg vg
hy red blood cells. Symptoms of B12 deficiency can vary from person to person
vg vg vg vg vg vg vg vg vg vg vg vg vg
, but there is some common signs and symptoms to look for.
vg vg vg vg vg vg vg vg vg vg vg
1.fatigue and weakness 2. Pale or yellowish skin. 3. Shortness of breath. 4. Dizzi vg vg vg vg vg vg vg vg vg vg vg vg vg
ness or Lightheadedness 5 Tingling or numbness. 6 Inflamed tongue. 7. changes
vg vg vg vg vg vg vg vg vg vg vg vg
in mental health vg vg
4. Iron deficiency anemia red blood cells are microcytic and hypochromic.
vg vg vg vg vg vg vg vg vg
5. Chronic Myeloid Leukemia (CML) is a type of cancer that affects the bone vg vg vg vg vg vg vg vg vg vg vg vg vg
marrow and blood cells. CML is primarily caused by genetic mutation known vg vg vg vg vg vg vg vg vg vg vg vg
as the Philadelphia chromosome. This mutation occurs when two specific gene
vg vg vg vg vg vg vg vg vg vg
s, the BCR which is the break point cluster region gene and the ABL1 Gene fuse
vg vg vg vg vg vg vg vg vg vg vg vg vg vg vg
d together. The presence of the Philadelphia chromosome leads to the producti
vg vg vg vg vg vg vg vg vg vg vg
on of an abnormal protein called BCR-
vg vg vg vg vg vg
ABL1 which then triggers the overgrowth of white blood cells in the bone marr
vg vg vg vg vg vg vg vg vg vg vg vg vg
ow.
6. Types of immunity. Innate immunity is the body's first line of defense and is p
vg vg vg vg vg vg vg vg vg vg vg vg vg vg
resent at birth. It simply provides a generalized, nonspecific response to a wide r
vg vg vg vg vg vg vg vg vg vg vg vg vg
ange or pathogen. In it, immunity includes physical barriers like the skin and m
vg vg vg vg vg vg vg vg vg vg vg vg vg
ucous membranes. Adaptive immunity. Adaptive immunity is also known as
vg v g vg vg vg vg vg vg vg vg
acquired. Immunity develops over time in response to exposure to specific path vg vg vg vg vg vg vg vg vg vg vg
ogens. It is highly specific and provides a targeted response to the particular pat
vg vg vg vg vg vg vg vg vg vg vg vg vg
hogen that is encountered. Passive immunity. Passive immunity is temporary
vg vg vg v g vg vg vg vg vg vg
and is acquired through another source rather than the body's own. System. As st
vg vg vg vg vg vg vg vg vg vg vg vg vg
, ated, it only provides short-
vg vg vg vg
term protection. It can be acquired naturally, such as the transfer of antibodies
vg vg vg vg vg vg vg vg vg vg vg vg