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NR 565 Midterm Exam Study Guide (Latest 2025 UPDATED): Advanced Pharmacology Fundamentals - Chamberlain

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NR 565 Midterm Exam Study Guide (Latest 2025 UPDATED): Advanced Pharmacology Fundamentals - Chamberlain

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9/28/26, 10:31 AM NR 565 Midterm Exam Study Guide (Latest 2025 UPDATED): Advanced Pharmacology Fundamentals - Chamberlain Flashcards |…




NR 565 Midterm Exam Study Guide (Latest 2025
UPDATED): Advanced Pharmacology Fundamentals
- Chamberlain

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Terms in this set (306)




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APRN prescribing role Prescriptive authority for nurse practitioners also
regulates prescribing rights beyond medications and
controlled substances. These rights include
therapeutic devices and services and are outlined in
state practice laws and regulations and include
Durable Medical Equipment (DME) such as
wheelchairs, power scooters, hospital beds, portable
oxygen equipment, handicap placards, etc. and
medical services such as Physical Therapy (PT),
Occupational Therapy (OT), home health services, etc.
Prescriptive authority encompasses more than writing
a prescription correctly. It requires adherence to
ethical guidelines to ensure that patients are
safeguarded from harm. Ethical prescribing starts with
being well-informed about medications. Mechanism
of action, efficacy, and safety are important
considerations, as are a patient's distinct needs and
circumstances, including the number of medications
prescribed (Mitchell & Oliphant, 2016). Most patients
receiving a prescription are taking other medications,
whether prescription or over-the-counter.
Appropriate selection, dosing, and duration of
pharmaceutical agents are key to maximizing
outcomes and minimizing adverse effects


benefits of full practice authority Nurse practitioners have the autonomy to evaluate
patients, diagnose, order and interpret tests, initiate
and manage treatments and prescribe medications,
including controlled substances without physician
oversight




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promoting positive outcomes through Administering medications and prescribing
prudent prescribing practices medications are two distinct processes. Prescription
writing requires prudent and deliberate decision-
making processes to maintain patient safety and
reduce liability, including:


*documentation of a provider-patient relationship for
the recipient of the prescribed medications


*documentation of a thorough history and physical
examination for the recipient


*documentation of discussions regarding risk factors,
side effects, or therapy options


*documentation of drug monitoring or titration plan, if
applicable


*documentation of consultations, if any
avoidance of prescribing medications for self, family,
or friends


Rational drug selection requires a logical approach
that includes the formulation of a diagnosis based on
clinical reasoning and the selection and monitoring of
the most appropriate pharmacological treatment


Considerations include: Cost, guidelines, availability,
interactions, side effects, allergies, hepatic/renal
functions, need for monitoring, & special populations




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Beer's Criteria identifies drugs with a high likelihood of causing
adverse effects in older adults. Accordingly, drugs on
this list should generally be avoided in adults older
than 65 years except when the benefits are
significantly greater than the risks.


Pharmacodynamics the study of the biochemical and physiologic effects
of drugs on the body and the molecular mechanisms
by which those effects are produced


Pharmacokinetics the study of drug movement throughout the body


Pharmacogenomics the study of how genes affect a person's response to
drugs. The purpose of this is to combine the sciences
of genomics and pharmacology to provide
individualized, targeted, safe drug therapies to
patients


CYP450 inducers Inducers are xenobiotics (medications and
environmental agents) that elevate CYP450 enzyme
activity by increasing enzyme synthesis. This action
leads to additional sites available for
biotransformation. The increased number of sites
enhances medication metabolism, decreasing the
concentration of the "parent drug" while increasing
metabolite production.


Inducers = Increase medication metabolism


(Carbamazepine, Rifampin, Alcohol, Phenytoin,
Griseofulvin, Phenobarbital, Sulfonylureas)




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