Test Bank for Nursing Pharmacology, 2nd Edition by Kimberly
Ernstmeyer & Elizabeth Christman | All Chapters | Questions,
Answers & Rationales 2027
, TABLE OF CONTENTS
Textbook chapters
Chapter 1: Pharmacokinetics & Pharmacodynamics: Includes
basic concepts such as
absorption, distribution, metabolism, and excretion.
Chapter 2: Legal/Ethical: Covers safe medication administration,
legal guidelines, and
preventing medication errors.
Chapter 3: Antimicrobials: Focuses on various antimicrobial
therapies, including
penicillins, cephalosporins, antivirals, and antifungals.
Chapter 4: Autonomic Nervous System: Discusses medications
related to the
autonomic nervous system, including agonists and antagonists.
Chapter 5: Respiratory System: Covers medications used for
respiratory disorders,
such as antihistamines, decongestants, and corticosteroids.
Chapter 6: Cardiovascular & Renal Systems: Addresses
medications for the
cardiovascular and renal systems, including antiarrhythmics, diuretics,
and
antihypertensives.
Chapter 7: Gastrointestinal System: Focuses on medications for
the GI system, such as
antiulcer medications, laxatives, and antiemetics.
Chapter 8: Central Nervous System: Covers CNS depressants,
stimulants,
antidepressants, and anticonvulsants.
Chapter 9: Endocrine System: Explores endocrine medications,
including
corticosteroids, antidiabetics, and thyroid medications.
Chapter 10: Analgesics & Musculoskeletal System: Includes
nonopioid and opioid
analgesics, as well as anesthetics.
,CHAPTER 1 — PHARMACOKINETICS &
PHARMACODYNAMICS
Question 1
A nurse is teaching a newly licensed nurse about drug
absorption. Which factor primarily affects the rate of
absorption after oral administration?
A. Volume of
distribution
B. Gastric emptying
time
C. Hepatic enzyme
activity
D. Protein binding
Correct answer: B. Gastric emptying time
Rationale:
B is correct. Gastric emptying time determines how quickly
an orally administered drug reaches the small intestine,
where most absorption occurs; faster emptying → more
rapid absorption.
A(Volume of distribution) affects distribution, not initial
absorption rate.
C (Hepatic enzyme activity) influences metabolism (first-
pass effect) and clearance, not the absorption rate from the
GI tract.
D (Protein binding) affects free drug available for
distribution and action, not the physical process/rate of
absorption across the GI mucosa.
, Question 2
A 68-year-old patient with decreased renal function is
prescribed a drug that is 90% renally excreted unchanged.
Which pharmacokinetic change is most likely and requires
nurse action?
A. Increased hepatic metabolism leading to subtherapeutic levels
Ernstmeyer & Elizabeth Christman | All Chapters | Questions,
Answers & Rationales 2027
, TABLE OF CONTENTS
Textbook chapters
Chapter 1: Pharmacokinetics & Pharmacodynamics: Includes
basic concepts such as
absorption, distribution, metabolism, and excretion.
Chapter 2: Legal/Ethical: Covers safe medication administration,
legal guidelines, and
preventing medication errors.
Chapter 3: Antimicrobials: Focuses on various antimicrobial
therapies, including
penicillins, cephalosporins, antivirals, and antifungals.
Chapter 4: Autonomic Nervous System: Discusses medications
related to the
autonomic nervous system, including agonists and antagonists.
Chapter 5: Respiratory System: Covers medications used for
respiratory disorders,
such as antihistamines, decongestants, and corticosteroids.
Chapter 6: Cardiovascular & Renal Systems: Addresses
medications for the
cardiovascular and renal systems, including antiarrhythmics, diuretics,
and
antihypertensives.
Chapter 7: Gastrointestinal System: Focuses on medications for
the GI system, such as
antiulcer medications, laxatives, and antiemetics.
Chapter 8: Central Nervous System: Covers CNS depressants,
stimulants,
antidepressants, and anticonvulsants.
Chapter 9: Endocrine System: Explores endocrine medications,
including
corticosteroids, antidiabetics, and thyroid medications.
Chapter 10: Analgesics & Musculoskeletal System: Includes
nonopioid and opioid
analgesics, as well as anesthetics.
,CHAPTER 1 — PHARMACOKINETICS &
PHARMACODYNAMICS
Question 1
A nurse is teaching a newly licensed nurse about drug
absorption. Which factor primarily affects the rate of
absorption after oral administration?
A. Volume of
distribution
B. Gastric emptying
time
C. Hepatic enzyme
activity
D. Protein binding
Correct answer: B. Gastric emptying time
Rationale:
B is correct. Gastric emptying time determines how quickly
an orally administered drug reaches the small intestine,
where most absorption occurs; faster emptying → more
rapid absorption.
A(Volume of distribution) affects distribution, not initial
absorption rate.
C (Hepatic enzyme activity) influences metabolism (first-
pass effect) and clearance, not the absorption rate from the
GI tract.
D (Protein binding) affects free drug available for
distribution and action, not the physical process/rate of
absorption across the GI mucosa.
, Question 2
A 68-year-old patient with decreased renal function is
prescribed a drug that is 90% renally excreted unchanged.
Which pharmacokinetic change is most likely and requires
nurse action?
A. Increased hepatic metabolism leading to subtherapeutic levels
