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Summary 3.4 Problem 1

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Summary for course 3.4 problem 1 depression

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PROBLEM 1

1.1 LEARNING GOALS
 What is depression?
 What are the symptoms (DSM-5)?
 How can depression be distinguished from a general temporary low mood?
 What are the different trajectories of the development of depression?
 What is the prevalence and demographics?
 What is the difference between depression and other general mood disorders?

WHO GLOBAL HEALTH ESTIMATES
- common mental disorders are: depressive disorders and anxiety disorders (are
usually comorbid)
- depression is the largest contributor to global disability and suicide deaths
- risk of depression is increased by poverty, unemployment, major life events, physical
illness and problems of drug/alcohol abuse
- depressive disorders:
o characterized by sadness, loss of interest or pleasure, feelings of guilt or low
self-worth, disturbed sleep or appetite, tiredness, poor concentration for at
least 2 weeks
o impairs person’s ability to cope with daily life, can be long lasting or recurrent
o distinct from feelings of sadness, stress or fear anyone can experience
o 2 main sub categories:
 major depressive disorder / depressive episode: mild, moderate or
severe episode
 dysthymia: persistent or chronic form of mild depression, less intense
than depressive episodes and lasts longer (at least 3 symptoms for at
least for 2 years in adults and 1 year in adolescents and children)
o also important: depression in people with or without manic episodes (bipolar)

Prevalence:
- over 300 million people suffer from depression (2015), around 4.4% of the
population  half of these people live in the South-East Asia region and Western
Pacific Region (India and China!)
o anxiety is 3.6% of the global population in comparison
- people living with depression increased 18.4% between 2005-2015
- depression is more common among females (5.1%) than males (3.6%)
- prevalence peaks in older adulthood (above 7.5% among females and above 5.5%
among males aged 55-74)
- also occurs in children and adolescents but at lower levels
- health loss: depressive disorders lead to 50 million Years Lived with Disability (YLD)
globally, 80% of it occurs in low- and middle-income countries
- suicide: accounted for 1.5% of all deaths, more than 700.000 people in 2015, male
suicide rates are higher than females, 78% of suicides occur in low- to middle-
income countries

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