NSG5003 Study Guide Questions with Verified
Correct Answers
Inserting bone marrow cells into an individual who produces abnormal erythrocytes is
an example of what type of therapy?
Somatic cell
DNA replication requires the enzyme DNA polymerase to:
Travel along the single DNA strand, adding the correct nucleotide to the new strand
Transcription is best defined as a process by which:
RNA is synthesized from a DNA template.
The purpose of a staining technique of chromosomes such as Giemsa is to:
Allow for the numbering of chromosomes and the identification of variations.
An amniocentesis indicates a neural tube defect when an increase in which protein is
evident?
Alpha fetoprotein
An amniocentesis is recommended for pregnant women who:
Have a family history of genetic disorders
The most clinically useful technique for prenatal diagnosis of chromosomal
abnormalities at 3 months' (12 weeks') gestation is:
Chorionic villus sampling
The term for an error in which homologous chromosomes fail to separate during
meiosis or mitosis is:
,Nondisjunction
Which clinical manifestations would be expected for a child who has complete trisomy
of the twenty-first chromosome?
An IQ of 25 to 70, low nasal bridge, protruding tongue, and flat, low-set ears
What is the most common cause of Down syndrome?
Maternal nondisjunction
What syndrome, characterized by an absent homologous X chromosome with only a
single X chromosome, exhibits features that include a short stature, widely spaced
nipples, and webbed neck?
Cri du chat
A person with 47, XXY karyotype has the genetic disorder resulting in which
syndrome?
Klinefelter
What is the chromosomal variation that causes Klinefelter syndrome?
Nondisjunction of X chromosome in the mother
What is the second most commonly recognized genetic cause of mental retardation?
Fragile X syndrome
What is the blood type of a person who is heterozygous, having A and B alleles as
codominant?
AB
, A couple has two children diagnosed with an autosomal dominant genetic disease. What
is the probability that the next child will have the same genetic disease?
One half
When a child inherits a disease that is autosomal recessive, it is inherited from:
Both parents
People diagnosed with neurofibromatosis have varying degrees of the condition because
of the genetic principle of:
Expressivity
Which genetic disease has been linked to a mutation of the tumor-suppressor gene?
Retinoblastoma
Cystic fibrosis is caused by what type of gene?
Autosomal recessive
Which is an important criterion for discerning autosomal recessive inheritance?
Consanguinity is sometimes present.
Consanguinity refers to the mating of persons:
Having common family relations
Males, having only one X chromosome (as is expected), are said to be:
Hemizygous
Males are more often affected by which type of genetic disease?
Sex-linked recessive
Correct Answers
Inserting bone marrow cells into an individual who produces abnormal erythrocytes is
an example of what type of therapy?
Somatic cell
DNA replication requires the enzyme DNA polymerase to:
Travel along the single DNA strand, adding the correct nucleotide to the new strand
Transcription is best defined as a process by which:
RNA is synthesized from a DNA template.
The purpose of a staining technique of chromosomes such as Giemsa is to:
Allow for the numbering of chromosomes and the identification of variations.
An amniocentesis indicates a neural tube defect when an increase in which protein is
evident?
Alpha fetoprotein
An amniocentesis is recommended for pregnant women who:
Have a family history of genetic disorders
The most clinically useful technique for prenatal diagnosis of chromosomal
abnormalities at 3 months' (12 weeks') gestation is:
Chorionic villus sampling
The term for an error in which homologous chromosomes fail to separate during
meiosis or mitosis is:
,Nondisjunction
Which clinical manifestations would be expected for a child who has complete trisomy
of the twenty-first chromosome?
An IQ of 25 to 70, low nasal bridge, protruding tongue, and flat, low-set ears
What is the most common cause of Down syndrome?
Maternal nondisjunction
What syndrome, characterized by an absent homologous X chromosome with only a
single X chromosome, exhibits features that include a short stature, widely spaced
nipples, and webbed neck?
Cri du chat
A person with 47, XXY karyotype has the genetic disorder resulting in which
syndrome?
Klinefelter
What is the chromosomal variation that causes Klinefelter syndrome?
Nondisjunction of X chromosome in the mother
What is the second most commonly recognized genetic cause of mental retardation?
Fragile X syndrome
What is the blood type of a person who is heterozygous, having A and B alleles as
codominant?
AB
, A couple has two children diagnosed with an autosomal dominant genetic disease. What
is the probability that the next child will have the same genetic disease?
One half
When a child inherits a disease that is autosomal recessive, it is inherited from:
Both parents
People diagnosed with neurofibromatosis have varying degrees of the condition because
of the genetic principle of:
Expressivity
Which genetic disease has been linked to a mutation of the tumor-suppressor gene?
Retinoblastoma
Cystic fibrosis is caused by what type of gene?
Autosomal recessive
Which is an important criterion for discerning autosomal recessive inheritance?
Consanguinity is sometimes present.
Consanguinity refers to the mating of persons:
Having common family relations
Males, having only one X chromosome (as is expected), are said to be:
Hemizygous
Males are more often affected by which type of genetic disease?
Sex-linked recessive
