NSG5003 Advanced Patho Immunity and
Infection Questions with Verified Correct
Answers
Hypersensitivity is best defined as a(an):
A) Disturbance in the immunologic tolerance of self-antigens
B) Immunologic reaction of one person to the tissue of another person
C) Altered immunologic response to an antigen that results in disease
D) Undetectable immune response in the presence of antigens
C) Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called:
A) Hemolytic shock
B) Anaphylaxis
C) Necrotizing vasculitis
D) Systemic erythematosus
B) Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins?
A) IgE
B) IgG
C) IgM
D) T cells
,A) IgE
Which type of antibody is involved in type I hypersensitivity reaction?
A) IgA
B) IgE
C) IgG
D) IgM
B) IgE
Blood transfusion reactions are an example of:
A) Autoimmunity
B) Alloimmunity
C) Homoimmunity
D) Hypersensitivity
B) Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated?
A) Neutrophils
B) Monocytes
C) Eosinophils
D) T lymphocytes
C) Eosinophils
,During an IgE-mediated hypersensitivity reaction, what causes bronchospasm?
A) Bronchial edema caused by the chemotactic factor of anaphylaxis
B) Bronchial edema caused by binding of the cytotropic antibody
C) Smooth muscle contraction caused by histamine bound to H1 receptors
D) Smooth muscle contraction caused by histamine bound to H2 receptors
C) Smooth muscle contraction caused by histamine bound to H1 receptors
During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a
result of which receptor action?
A) Histamine bound to H2
B) Chemotactic factor binding to the receptor
C) Epinephrine bound to mast cells
D) Acetylcholine bound to mast cells
A) Histamine bound to H2
What characteristic do atopic individuals have that make them genetically predisposed
to develop allergies?
A) Greater quantities of histamine
B) More histamine receptors
C) Greater quantities of IgE
D) A deficiency in epinephrine
C) Greater quantities of IgE
, What is the mechanism that results in type II hypersensitivity reactions?
A) Antibodies coat mast cells by binding to receptors that signal its degranulation,
followed by a discharge of preformed mediators.
B) Antibodies bind to soluble antigens that were released into body fluids, and the
immune complexes are then deposited in the tissues.
C) Cytotoxic T lymphocytes or lymphokine-producing helper T 1 cells directly attack
and destroy cellular targets.
D) Antibodies bind to the antigens on the cell surface.
D) Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the
erythrocytes are destroyed by:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
D) Natural killer cells
A) Complement-mediated cell lysis
When antibodies are formed against red blood cell antigens of the Rh system, the blood
cells are destroyed by:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
Infection Questions with Verified Correct
Answers
Hypersensitivity is best defined as a(an):
A) Disturbance in the immunologic tolerance of self-antigens
B) Immunologic reaction of one person to the tissue of another person
C) Altered immunologic response to an antigen that results in disease
D) Undetectable immune response in the presence of antigens
C) Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called:
A) Hemolytic shock
B) Anaphylaxis
C) Necrotizing vasculitis
D) Systemic erythematosus
B) Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins?
A) IgE
B) IgG
C) IgM
D) T cells
,A) IgE
Which type of antibody is involved in type I hypersensitivity reaction?
A) IgA
B) IgE
C) IgG
D) IgM
B) IgE
Blood transfusion reactions are an example of:
A) Autoimmunity
B) Alloimmunity
C) Homoimmunity
D) Hypersensitivity
B) Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated?
A) Neutrophils
B) Monocytes
C) Eosinophils
D) T lymphocytes
C) Eosinophils
,During an IgE-mediated hypersensitivity reaction, what causes bronchospasm?
A) Bronchial edema caused by the chemotactic factor of anaphylaxis
B) Bronchial edema caused by binding of the cytotropic antibody
C) Smooth muscle contraction caused by histamine bound to H1 receptors
D) Smooth muscle contraction caused by histamine bound to H2 receptors
C) Smooth muscle contraction caused by histamine bound to H1 receptors
During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a
result of which receptor action?
A) Histamine bound to H2
B) Chemotactic factor binding to the receptor
C) Epinephrine bound to mast cells
D) Acetylcholine bound to mast cells
A) Histamine bound to H2
What characteristic do atopic individuals have that make them genetically predisposed
to develop allergies?
A) Greater quantities of histamine
B) More histamine receptors
C) Greater quantities of IgE
D) A deficiency in epinephrine
C) Greater quantities of IgE
, What is the mechanism that results in type II hypersensitivity reactions?
A) Antibodies coat mast cells by binding to receptors that signal its degranulation,
followed by a discharge of preformed mediators.
B) Antibodies bind to soluble antigens that were released into body fluids, and the
immune complexes are then deposited in the tissues.
C) Cytotoxic T lymphocytes or lymphokine-producing helper T 1 cells directly attack
and destroy cellular targets.
D) Antibodies bind to the antigens on the cell surface.
D) Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the
erythrocytes are destroyed by:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
D) Natural killer cells
A) Complement-mediated cell lysis
When antibodies are formed against red blood cell antigens of the Rh system, the blood
cells are destroyed by:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
