Chapter 01
1. Which of the following organs undergoes atrophy during childhood and adolescence? [Multiple Choice]
a. Uterus
b. Thymus ✔
c. Thyroid
d. Adrenals
ANS: B
DIF: 2REF: P. 13OBJ: 8
2. Chronic hemolysis is characterized by accumulation of an iron-containing brown pigment in the cytoplasm of
liver cells. What is this brown pigment called? [Multiple Choice]
a. Melanin
b. Tyrosin
c. Hemosiderin ✔
d. Bilirubin
ANS: C
DIF: 3REF: P. 15OBJ: 11
3. When irritated by chronic exposure to cigarette smoke, columnar bronchial epithelium changes into stratified
squamous epithelium. What is this physiologic change an example of? [Multiple Choice]
a. Hypertrophy
b. Hyperplasia
c. Atrophy
d. Metaplasia ✔
ANS: D
DIF: 3REF: P. 14OBJ: 10
4. Which of the following is a sign of irreversible cell injury? [Multiple Choice]
a. Apoptosis
,b. Pyknosis ✔
c. Hydropic change
d. Vacuolar degeneration
ANS: B
DIF: 1REF: P. 10OBJ: 5
5. Which organ is metastatic calcification typically associated with? [Multiple Choice]
a. Liver
b. Brain
c. Pancreas
d. Kidney ✔
ANS: D
DIF: 3REF: P. 18OBJ: 16
6. Which of the following is an oxygen radical? [Multiple Choice]
a. Hydrogen peroxide ✔
b. Acid hydrolase
c. Carbon tetrachloride
d. Lipofuscin
ANS: A
DIF: 2REF: P. 11OBJ: 6
7. Which of the following would not be considered a pathogenetic mechanism for causing cellular injury? [Multiple
Choice]
a. Toxins
b. Microbial pathogens
c. Genetic disturbances
d. Coagulation ✔
ANS: D
DIF: 2REF: P. 7OBJ: 6
,8. Which statement best describes a fatty liver? [Multiple Choice]
a. There is an extracellular accumulation of intermediate metabolites.
b. There is an intracellular accumulation of intermediate metabolites. ✔
c. Extracellular sodium has accumulated in the liver.
d. Intracellular sodium has accumulated in the liver.
ANS: B
DIF: 3REF: P. 15OBJ: 12
9. What best describes hydropic change at the cellular level? [Multiple Choice]
a. An equal level of water inside and outside the cell
b. A decrease of water in the cytoplasm
c. An increase of water in the cytoplasm ✔
d. A result of irreversible cell injury
ANS: C
DIF: 2REF: P. 8OBJ: 5
10. Which type of necrosis is found in the lungs of those with tuberculosis? [Multiple Choice]
a. Coagulation necrosis
b. Liquefactive necrosis
c. Caseous necrosis ✔
d. Fibrinoid necrosis
ANS: C
DIF: 3REF: P. 17OBJ: 15
11. What type of cardiac tissue change is seen in myocardial infarction? [Multiple Choice]
a. Dystrophic calcification
b. Metastatic calcification
c. Fibrinoid necrosis
d. Coagulation necrosis ✔
, ANS: D
DIF: 3REF: P. 17OBJ: 15
12. Liquefactive necrosis caused by infarction is typically seen in which organ? [Multiple Choice]
a. Heart
b. Brain ✔
c. Liver
d. Kidney
ANS: B
DIF: 3REF: P. 17OBJ: 15
13. Minerals like copper and zinc play what role in cellular function? [Multiple Choice]
a. They assist maintaining cytoplasm homeostasis.
b. They assist in the removal of cellular waste products.
c. They are necessary for ATP production.
d. They enable several important enzymes to function. ✔
ANS: D
DIF: 1REF: P. 8OBJ: 2
14. The inhibition of ATP production caused by hypoxia will result in which cellular outcome? [Multiple Choice]
a. Increased ribosome production
b. Dilation and fragmentation of the rough endoplasmic reticulum ✔
c. Mitochondrial atrophy
d. Increased alkalinity of the hyaloplasm
ANS: B
DIF: 1REF: P. 8OBJ: 4
15. Enlargement of the heart, caused by hypertension, is a result of which physiologic process? [Multiple Choice]
a. Hypertrophy ✔
b. Atrophy
1. Which of the following organs undergoes atrophy during childhood and adolescence? [Multiple Choice]
a. Uterus
b. Thymus ✔
c. Thyroid
d. Adrenals
ANS: B
DIF: 2REF: P. 13OBJ: 8
2. Chronic hemolysis is characterized by accumulation of an iron-containing brown pigment in the cytoplasm of
liver cells. What is this brown pigment called? [Multiple Choice]
a. Melanin
b. Tyrosin
c. Hemosiderin ✔
d. Bilirubin
ANS: C
DIF: 3REF: P. 15OBJ: 11
3. When irritated by chronic exposure to cigarette smoke, columnar bronchial epithelium changes into stratified
squamous epithelium. What is this physiologic change an example of? [Multiple Choice]
a. Hypertrophy
b. Hyperplasia
c. Atrophy
d. Metaplasia ✔
ANS: D
DIF: 3REF: P. 14OBJ: 10
4. Which of the following is a sign of irreversible cell injury? [Multiple Choice]
a. Apoptosis
,b. Pyknosis ✔
c. Hydropic change
d. Vacuolar degeneration
ANS: B
DIF: 1REF: P. 10OBJ: 5
5. Which organ is metastatic calcification typically associated with? [Multiple Choice]
a. Liver
b. Brain
c. Pancreas
d. Kidney ✔
ANS: D
DIF: 3REF: P. 18OBJ: 16
6. Which of the following is an oxygen radical? [Multiple Choice]
a. Hydrogen peroxide ✔
b. Acid hydrolase
c. Carbon tetrachloride
d. Lipofuscin
ANS: A
DIF: 2REF: P. 11OBJ: 6
7. Which of the following would not be considered a pathogenetic mechanism for causing cellular injury? [Multiple
Choice]
a. Toxins
b. Microbial pathogens
c. Genetic disturbances
d. Coagulation ✔
ANS: D
DIF: 2REF: P. 7OBJ: 6
,8. Which statement best describes a fatty liver? [Multiple Choice]
a. There is an extracellular accumulation of intermediate metabolites.
b. There is an intracellular accumulation of intermediate metabolites. ✔
c. Extracellular sodium has accumulated in the liver.
d. Intracellular sodium has accumulated in the liver.
ANS: B
DIF: 3REF: P. 15OBJ: 12
9. What best describes hydropic change at the cellular level? [Multiple Choice]
a. An equal level of water inside and outside the cell
b. A decrease of water in the cytoplasm
c. An increase of water in the cytoplasm ✔
d. A result of irreversible cell injury
ANS: C
DIF: 2REF: P. 8OBJ: 5
10. Which type of necrosis is found in the lungs of those with tuberculosis? [Multiple Choice]
a. Coagulation necrosis
b. Liquefactive necrosis
c. Caseous necrosis ✔
d. Fibrinoid necrosis
ANS: C
DIF: 3REF: P. 17OBJ: 15
11. What type of cardiac tissue change is seen in myocardial infarction? [Multiple Choice]
a. Dystrophic calcification
b. Metastatic calcification
c. Fibrinoid necrosis
d. Coagulation necrosis ✔
, ANS: D
DIF: 3REF: P. 17OBJ: 15
12. Liquefactive necrosis caused by infarction is typically seen in which organ? [Multiple Choice]
a. Heart
b. Brain ✔
c. Liver
d. Kidney
ANS: B
DIF: 3REF: P. 17OBJ: 15
13. Minerals like copper and zinc play what role in cellular function? [Multiple Choice]
a. They assist maintaining cytoplasm homeostasis.
b. They assist in the removal of cellular waste products.
c. They are necessary for ATP production.
d. They enable several important enzymes to function. ✔
ANS: D
DIF: 1REF: P. 8OBJ: 2
14. The inhibition of ATP production caused by hypoxia will result in which cellular outcome? [Multiple Choice]
a. Increased ribosome production
b. Dilation and fragmentation of the rough endoplasmic reticulum ✔
c. Mitochondrial atrophy
d. Increased alkalinity of the hyaloplasm
ANS: B
DIF: 1REF: P. 8OBJ: 4
15. Enlargement of the heart, caused by hypertension, is a result of which physiologic process? [Multiple Choice]
a. Hypertrophy ✔
b. Atrophy