1807NRS EOT Practice Exam Questions with Correct Answers
(Grade A+)
Question 1: Action of b1 antagonist
Answer: decrease HR and GIT
Question 2: Action of b2 agonist
Answer: raise BP and HR and ↓ GIT
Question 3: Muscarinic antagonists action
Answer: bronchodilation, ↓
cognitive processes = sedation, ↓ peristalsis and gastric secretion
and tachycardia
Question 4: Muscarinic agonist action
Answer: bradycardia, hypotension,
pupil constriction, diaphoresis and bronchoconstriction
Question 5: Where are nicotinic receptors located
Answer: PNS and SNS
smooth and cardiac muscle, NMJ of skeletal muscles and CNS
Question 6: MOA of nicotinic agonist
Answer: skeletal tremors, relaxation and
wellbeing sensations, adrenal medulla stimulation (↑HR), ↑ ANS tone
(↑NP, GI-diarrhoea)
Question 7: Adverse effects of nicotinic receptor agonist
Answer: smoking can
cause HTN, nausea, insomnia
Question 8: Nursing care for nicotinic agonist
Answer: monitor skeletal
muscle weakenss and nicotine withdrawl symptoms
Page 1
,Question 9: How do chemical mediators communicate
Answer: cell to cell
Question 10: What are the 4 classifications of chemical mediators, how they send signals and example
for each
Answer: neurone (Ach) - synapse,
endocrine (Insulin) - through bloodstream, paracrine (Histamine) -
target cell is close by and autocrine (Cytokines) - target cell is the
same
Question 11: Where is histamine highly concentrated in the body
Answer: lungs,
skin, GI and CNS
Question 12: Role of histamine in the body
Answer: allergic and inflammatory
reactions, and gastric acid secretion
Question 13: MOA of anti-histamine drugs
Answer: antagonise H1 receptors to
treat allergies
Question 14: Difference between 1st and 2nd generation anti-histamine drugs
Answer: 1st gen crosses BBB (sedating) and 2nd only has small
amounts crossing BBB
Question 15: S/E of anti-histamine drugs
Answer: dry mouth and drowsiness
Question 16: MOA of H2 antagonist drugs
Answer: inhibits gastric secretion
Question 17: What are prostoglandins synthesised from
Answer: omega 3 and 6
Page 2
, Question 18: What are some effects of PGs
Answer: SM constriction,
vasodilation, aggregation of platelets, sensititses neurons to pain,
mediation of inflammation, produces fever, inhibits acid secretion in
stomach and relaxes uterine muscle
Question 19: What does arachidonic acid produce
Answer: inflammatory
mediators
Question 20: MOA of NSAIDs
Answer: inhibit PG by interfering with COX
enzymes
Question 21: Where are COXI found
Answer: stomach, intestines, kidneys and
platelets
Question 22: Where are COXII found
Answer: periphial tissues
Question 23: What are some S/Es of nonselective blocking of COX I
Answer: irritation of GI mucosa, HCL- acid secretion, bleeding times, alter
renal functions
Question 24: What does blocking COX enzymes do
Answer: ↓ pain and
inflammation
Question 25: Examples of non-specific COX I inhibitors
Answer: aspirin,
ibuprofen, infomethicin, diclofenac
Page 3
(Grade A+)
Question 1: Action of b1 antagonist
Answer: decrease HR and GIT
Question 2: Action of b2 agonist
Answer: raise BP and HR and ↓ GIT
Question 3: Muscarinic antagonists action
Answer: bronchodilation, ↓
cognitive processes = sedation, ↓ peristalsis and gastric secretion
and tachycardia
Question 4: Muscarinic agonist action
Answer: bradycardia, hypotension,
pupil constriction, diaphoresis and bronchoconstriction
Question 5: Where are nicotinic receptors located
Answer: PNS and SNS
smooth and cardiac muscle, NMJ of skeletal muscles and CNS
Question 6: MOA of nicotinic agonist
Answer: skeletal tremors, relaxation and
wellbeing sensations, adrenal medulla stimulation (↑HR), ↑ ANS tone
(↑NP, GI-diarrhoea)
Question 7: Adverse effects of nicotinic receptor agonist
Answer: smoking can
cause HTN, nausea, insomnia
Question 8: Nursing care for nicotinic agonist
Answer: monitor skeletal
muscle weakenss and nicotine withdrawl symptoms
Page 1
,Question 9: How do chemical mediators communicate
Answer: cell to cell
Question 10: What are the 4 classifications of chemical mediators, how they send signals and example
for each
Answer: neurone (Ach) - synapse,
endocrine (Insulin) - through bloodstream, paracrine (Histamine) -
target cell is close by and autocrine (Cytokines) - target cell is the
same
Question 11: Where is histamine highly concentrated in the body
Answer: lungs,
skin, GI and CNS
Question 12: Role of histamine in the body
Answer: allergic and inflammatory
reactions, and gastric acid secretion
Question 13: MOA of anti-histamine drugs
Answer: antagonise H1 receptors to
treat allergies
Question 14: Difference between 1st and 2nd generation anti-histamine drugs
Answer: 1st gen crosses BBB (sedating) and 2nd only has small
amounts crossing BBB
Question 15: S/E of anti-histamine drugs
Answer: dry mouth and drowsiness
Question 16: MOA of H2 antagonist drugs
Answer: inhibits gastric secretion
Question 17: What are prostoglandins synthesised from
Answer: omega 3 and 6
Page 2
, Question 18: What are some effects of PGs
Answer: SM constriction,
vasodilation, aggregation of platelets, sensititses neurons to pain,
mediation of inflammation, produces fever, inhibits acid secretion in
stomach and relaxes uterine muscle
Question 19: What does arachidonic acid produce
Answer: inflammatory
mediators
Question 20: MOA of NSAIDs
Answer: inhibit PG by interfering with COX
enzymes
Question 21: Where are COXI found
Answer: stomach, intestines, kidneys and
platelets
Question 22: Where are COXII found
Answer: periphial tissues
Question 23: What are some S/Es of nonselective blocking of COX I
Answer: irritation of GI mucosa, HCL- acid secretion, bleeding times, alter
renal functions
Question 24: What does blocking COX enzymes do
Answer: ↓ pain and
inflammation
Question 25: Examples of non-specific COX I inhibitors
Answer: aspirin,
ibuprofen, infomethicin, diclofenac
Page 3
