EvolutionaryAnalysis5thEdition
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byJonC.Herron;ScottFreemanChapters1-20
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,TABLEOFCONTENTS e e e
1ACaseforEvolutionaryThinking:UnderstandingHIV 2ThePatternofEvolution
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3 Evolution by Natural Selection 4 Estimating
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EvolutionaryTrees 5VariationAmongIndividuals
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6MendelianGeneticsinPopulationsI:SelectionandMutation 7MendelianGeneticsinPopulationsII:
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Migration,Drift,& NonrandomMating
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8 EvolutionatMultipleLoci:LinkageandSex e e e e e e
9 EvolutionatMultipleLoci:QuantitativeGenetics e e e e e
10 StudyingAdaptation:EvolutionaryAnalysisofFormand Function e e e e e e e
11 SexualSelection e
12 TheEvolutionofSocialBehavior
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13 AgingandOtherLife-HistoryCharacters 14EvolutionandHuman
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Health
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15GenomeEvolutionandtheMolecularBasisofAdaptation 16MechanismsofSpeciation
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17TheOriginsofLifeandPrecambrianEvolution 18EvolutionandtheFossilRecord
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19DevelopmentandEvolution 20HumanEvolution
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,Chapter1 ACase for Evolutionary Thinking:Understanding HIV
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1) In which ofthe followingregionshas AIDSkilled the largest numberof individuals?
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A) India
B) Sub-SaharanAfrica e
C) United States e
D) China
E) United
Kingdom Answer:
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BSection: 1.1
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Skill: Knowledge/Comprehension
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2) The HIV virus contains allofthefollowing components except
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A) integrase
B) double-strandedRNA e
C) single-strandedRNA e
D) reversetranscriptase e
E) proteas
e Answer: B
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Section:
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1.1
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Skill: Knowledge/Comprehension
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3) The acronym HIVstands forwhichof the following?
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A) human intercellular virus e e
B) human immunevirus e e
C) humanimmunodeficiencyvirus e e
D) human immunityvirus e e
E) humanimmunodeficiency e
vector Answer: C
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Section: 1.1 e
Skill: Knowledge/Comprehension
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4) Which ofthe followingenzymes is responsible fortranscribingviral RNA intoDNA?
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A) RNApolymerase e
B) reversetranscriptase e
C) DNApolymerase e
D) reverseintegrase e
E) RNA
duplicase
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Answer: B
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Section: 1.1
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Skill: Knowledge/Comprehension
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, 5) Theproteinsthat enablethe HIV virus to bindto cells are typicallyCD4 andCCR5. On
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what typeof cells aretheseproteinstypicallyobserved?
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A) plasmacells e
B) dendriticcells e
C) effectorhelperTcells e e e
D) memoryhelperT cells e e e
E) both C e
and
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DAnswer: E
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Section:
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1.1
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Skill: Knowledge/Comprehension
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6) The AIDSphase of HIVinfection begins whentheconcentrationofCD4 Tcells inthe
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blood dropsbelowwhatconcentration?
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A) 2,000cells percubicmillimeter e e e e
B) 1,000cells percubic millimeter e e e e
C) 500cells percubicmillimeter
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D) 200cells per cubicmillimeter
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E) NoCD4Tcellsaree e e e
observed. Answer: D
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Section: 1.1 e
Skill: Knowledge/Comprehension
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7) Which ofthe followingdrug categories are usedtotreat HIVinfections?
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A) integraseinhibitors e
B) proteaseinhibitors e
C) reversetranscriptaseinhibitors e e
D) DNAseinhibitors e
E) fusion
inhibitors
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Answer:
e D e
Section: 1.2
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Skill: Knowledge/Comprehension
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8) Coreceptor inhibitorsblock HIV infectionbypreventingwhich ofthe following? e e e e e e e e e e
A) bindingofthe HIV virion onto the plasmamembrane e e e e e e e e
B) bindingof the HIV virion onto the CCR5 receptor e e e e e e e e
C) bindingofthe HIV viriononto the gp120 protein e e e e e e e e
D) degradingthecoreceptor so thevirioncannot attach e e e e e e e
E) binding ofthe HIV virion onto theCD4 e e e e e e e
receptor Answer: B
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Section: 1.2 e
Skill: Application/Analysis
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9) What isthe effect ofthe∆32 allele of CCR5 on HIVbinding?
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