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ATI Pharmacology Proctored Exam | 500 Practice Questions, Nursing Pharmacology Review & Study Guide

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Prepare for ATI Pharmacology assessments with a comprehensive study resource focused on essential nursing pharmacology concepts and medication safety. This review material is designed to help nursing students strengthen their understanding of medications and apply pharmacologic principles to patient-care situations. Review key topics including medication classifications, therapeutic effects, adverse reactions, contraindications, precautions, drug interactions, routes of administration, dosage considerations, patient education, and nursing interventions. Practice-oriented review can help reinforce medication knowledge, clinical reasoning, and safe nursing care principles. Use this resource alongside your ATI coursework, nursing textbooks, instructor materials, and other approved educational resources. It is intended for educational study and review and can help students organize their pharmacology preparation, reinforce important concepts, and identify areas that require additional study before nursing assessments.

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A. One

A provider prescribes phenobarbital for a client (Medications with long half-lives remain at their therapeutic levels between doses for long
who has a seizure disorder. The medication has a periods of time. The nurse should expect to administer this medication once a day.)
long half-life of 4 days. How many times per day
should the nurse expect to administer this
medication?

A. One
B. Two
C. Three
D. Four




C. Liver failure
E. Concurrent use of medication the same pathway metabolizes

C. Liver failure decreases metabolism and thus increases the concentration of a medication.
This requires decreasing the dosage.
A staff educator is reviewing medication dosages
and factors that influence medication metabolism E. When the same pathway metabolizes two medications, they compete for metabolism, thereby
with a group of nurses at an in-service
increasing the concentration of one or both medications. This requires decreasing the dosage of
presentation. Which of the following factors
one or both
should the educator include as a reason to
administer lower medication dosages? (Select all
that apply.)

A. Increased renal secretion
B. Increased medication-metabolizing enzymes
C. Liver failure
D. Peripheral vascular disease
E. Concurrent use of medication the same
pathway metabolizes




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B. Ask the client to look up at the ceiling.
D. Drop the medication into the center of the client's conjunctival sac.
E. Instruct the client to close her eye gently after instillation
A nurse is preparing to administer eye drops to a
client. Which of the following actions should the (B. The client should look upward to keep the drops from falling onto her cornea.
nurse take? (Select all that apply.) D. The nurse should drop the medication into the
center of the conjunctival sac to promote distribution.
A. Have the client lie on her side. E. The client should close her eye gently to promote distribution of the medication)
B. Ask the client to look up at the ceiling.
C. Tell the client to blink when the drops enter
her eye.
D. Drop the medication into the center of the
client's conjunctival sac.
E. Instruct the client to close her eye gently after
instillation




C. "I will apply the patch to an area of skin with no hair."

(The client should apply the patch to a hairless area of skin to promote absorption of the
medication.)
A nurse is completing discharge teaching for a
client who has a new prescription for transdermal
patches. Which of the following statements
should the nurse identify as an indication that the
client understands the instructions?

A. "I will clean the site with an alcohol swab
before I apply the patch."
B. "I will rotate the application sites weekly."
C. "I will apply the patch to an area of skin with
no hair."
D. "I will place the new patch on the site of the
old patch.




ATI Pharmacology Proctored,
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Pharmacology
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Pharmacology
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A. Obtain a blood specimen immediately prior to administering the next dose of medication.

(To verify trough levels of a medication, the nurse should obtain a blood specimen immediately
before administering the next dose of medication.)

A nurse reviewing a client's medical record notes
a new prescription for verifying the trough level
of the client's medication. Which of the
following actions should the nurse take?

A. Obtain a blood specimen immediately prior to
administering the next dose of medication.
B. Verify that the client has been taking the
medication for 24 hr before obtaining a blood
specimen.
C. Ask the client to provide a urine specimen
after the next dose of medication.
D. Administer the medication,and obtain a blood
specimen 30 min late




A. Maintain skill competency.
C. Monitor for adverse effects.
D. Safeguard medications.
A nurse is preparing a client's medications. (A.maintaining skill competency and using appropriate administration techniques are legal
Which of the following actions should the nurse responsibilities of the nurse
take in following legal practice guidelines?
(Select all that apply.) C. A nurse is legally responsible for monitoring for side and adverse effects of medication
A. Maintain skill competency. D. Safeguarding of medications, such as controlled substances, is a legal responsibility of the
B. Determine the dosage. nurse)
C. Monitor for adverse effects.
D. Safeguard medications.
E. Identify the client's diagnosis




C. Routine

(A routine or standard prescription identifies medications to give on a regular schedule with or
A nurse reviewing a client's health record notes a without a termination date or a specific number of doses. The nurse will administer
new prescription for Lisinopril 10 mg PO once this medication every day until the provider discontinues it.)
every day. The nurse should identify this as
which of the following types of prescription?

A. Single
B. Stat
C. Routine
D. Standing




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D. Frequency

A nurse is reviewing a new prescription for (This prescription does not include the time or frequency of medication administration. The
Ondansetron 4 mg PO PRN for nausea and nurse must clarify this with the prescribing provide)
vomiting for a client who has Hyperemesis
Gravidarum. The nurse should clarify which of
the following parts of the prescription with the
provider?

A. Name
B. Dosage
C. Route
D. Frequency



A. Use of herbal teas
C. Current health status
E. Food allergies

A nurse is admitting a client and completing a (A. The nurse should inquire about the client's use of herbal products, which often contain
preassessment before administering medications. caffeine, prior to medication administration because caffeine can affect medication
Which of the following data should the nurse biotransformation
include in the preassessment? (Select all that
apply.) C. The nurse should review the client's current health status because new prescriptions can
cause alterations in current health status
A. Use of herbal teas
B. Daily fluid intake E. The nurse should inquire about food allergies during the preassessment to identify any
C. Current health status potential reactions or interactions)
D. Previous surgical history
E. Food allergies




B. "Another nurse should listen to the phone call."

(A second nurse should listen to a telephone prescription to prevent errors in communication.)

A nurse orienting a newly licensed nurse is
reviewing the procedure for taking a telephone
prescription. Which of the following statements
should the nurse identify as an indication that the
newly licensed nurse understands the process?

A. "A second nurse enters the prescription into
the client's medical record."
B. "Another nurse should listen to the phone
call."
C. "The provider can clarify the prescription
when he signs the health record."
D. "I should omit the 'read back' if this is a
one‑time prescription




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500
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Uploaded on
September 26, 2026
Number of pages
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