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NR507 Advanced Pathophysiology Final Exam

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Prepare for the NR507 Advanced Pathophysiology Final Exam with a focused review of essential concepts related to disease processes, physiological dysfunction, clinical manifestations, and underlying mechanisms of illness. This study resource is designed to help students organize key pathophysiology concepts, review important terminology, connect disease mechanisms with patient findings, and strengthen their understanding of complex physiological changes. Use this guide for exam preparation, coursework review, and reinforcement of advanced pathophysiology concepts across major body systems and disease conditions.

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Pathophysiology
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Terms in this set (51)



Acute renal failure Reversible
Determining prognosis- kidneys respond to diuretic with good output; this indicates
that kidneys are functioning well


Acute Pyelonephritis Diagnosing by clinical symptoms alone can be difficult; can be similar to cystitis


Diagnosis established by:
-Urine culture
-Urinalysis (WBC casts indicates pyelonephritis, but may not always be present)
-Signs/Symptoms
-Complicated pyelonephritis requires blood cultures and urinary tract imaging


Renal Calculi (Renal Stones) Goals of Treatment:
Manage acute pain
Promote passage of stone
Reduce size of stone
Prevent new stone formation


Chronic Renal Failure Chronic Kidney Disease (CKD) is a progressive loss of renal function associated with
systemic disease such as hypertension, diabetes mellitus (most significant risk factor),
systemic lupus erythematosus or intrinsic kidney disease
CKD stage is determined by estimates of GFR and albuminuria




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Who is a candidate for dialysis? End-stage renal disease (ESRD) is the final stage of CKD with the number one cause
being diabetes mellitus combined with hypertension. At this point, the patient is
completely dependent on dialysis to survive.
CKD is classified into five stages and is based on the patient's GFR rather than
symptoms.


Patients will need dialysis when the following symptoms are present:
--Metabolic acidosis.
--Hyperkalemia: Hyperkalemia in the presence of EKG changes (peaked T-waves) is an
indication for dialysis. --Hyperkalemia by itself is not an indication for dialysis.
--Drug toxicity: Drug toxicity due to the following drugs is an indication for dialysis
and include salicylates, Lithium, Isopropanol, Methanol and Ethylene glycol).
--Fluid volume overload that is not responsive to diuretics.
--Uremic symptoms due to nitrogenous wastes in the blood stream.


Stage I CKD There is kidney damage with normal or elevated GFR
90-120


Stage II CKD There is kidney damage with mild decrease in GFR
60-89


Stage III CKD There is a moderate decrease in GFR
30-59


Stage IV CKD There is a severe decrease in GFR
15-29


Stage V CKD Kidney failure- End-stage renal disease
<15 (dialysis) Once Stage IV is reached, progression to Stage V is inevitable as well as
dialysis or kidney transplant




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Pathophysiology
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Final Exam.pdf@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!$$$$$$$$$$$$$$$$$$$$$$
Pathophysiology Final Exam.pdfNR507- Advanced Pathophysiology Final Exam.pdf@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@

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