NCE CRNA EXAM |ACTUAL QUESTIONS AND
VERIFIED ANSWERS|BRAND NEW 2026-2027
UPDATE|GRADED A+
Question 1
The potency of local anesthetics increases as the:
A. Lipid Solubility Increases
B. pKa increases
C. Number of Double Bonds in the local anesthetic molecule increases
D. Molecular weight decreases
CORRECT ANSWER
Answer: A. lipid solubility increases
Explanation: Local anesthetic potency correlates directly with lipid solubility. In general,
lipid solubility increases with an increase in the total number of carbon atoms in the
molecule and by adding a halogen to the aromatic ring.
Question 2
Correct location of the catheter tip of a central venous line is in the:
A. Superior Vena Cava
B. Right Atrium
C. Right Ventricle
D. Pulmonary Artery
CORRECT ANSWER
Answer: A. Superior Vena Cava
1
, Explanation: The CVP catheter tip should not be allowed to migrate into the heart
chambers to avoid arrhythmias and perforation.
Question 3
The rapid shallow breathing index (RSBI) is useful in predicting successful weaning from
mechanical ventilation. Prior to extubation this index should be:
A. Between 300 and 400
B. Between 200 and 300
C. Between 100 and 200
D. Less than 100
CORRECT ANSWER
Answer: D. Less than 100
Explanation: RSBI is frequently used to help predict who can be successfully weaned
from mechanical ventilation. With the patient breathing spontaneously, the ventilatory
rate is divided by the tidal volume (liters). An RSBI of less than 100 can predict successful
extubation.
Question 4
The perception of an ordinarily non-noxious stimulus as pain is referred to as:
A. allodynia
B. anesthesia dolorosa
C. dysesthesia
D. hyperalgesia
CORRECT ANSWER
2
, Answer: A. Allodynia
Explanation: Allodynia is the perception of non-noxious stimuli as pain. Dysesthesia is an
unpleasant sensation without a stimulus. Hyperesthesia is an increased response to a
mild stimulus. Anesthesia dolorosa is pain in an area that lacks sensation.
Question 5
Pathophysiologic factors affecting the anesthetic management of patients with
hypothyroidism include:
A. Hypernatremia
B. Hyperglycemia
C. Difficulty with intubation and airway management
D. Increased blood viscosity due to elevated hematocrit
CORRECT ANSWER
Answer: C. Difficulty with intubation and airway management
Explanation: Potential problems of hypothyroidism include hypoglycemia, anemia,
hyponatremia and difficulty during intubation because of a large tongue or the presence
of a goiter. Hypothermia secondary to a low metabolic rate is a common postoperative
complication.
Question 6
Airway obstruction caused by the tongue falling posteriorly against the wall of the pharynx
is secondary to relaxation of the:
A. genioglossus muscle
B. longitudinal muscle of the tongue
3
VERIFIED ANSWERS|BRAND NEW 2026-2027
UPDATE|GRADED A+
Question 1
The potency of local anesthetics increases as the:
A. Lipid Solubility Increases
B. pKa increases
C. Number of Double Bonds in the local anesthetic molecule increases
D. Molecular weight decreases
CORRECT ANSWER
Answer: A. lipid solubility increases
Explanation: Local anesthetic potency correlates directly with lipid solubility. In general,
lipid solubility increases with an increase in the total number of carbon atoms in the
molecule and by adding a halogen to the aromatic ring.
Question 2
Correct location of the catheter tip of a central venous line is in the:
A. Superior Vena Cava
B. Right Atrium
C. Right Ventricle
D. Pulmonary Artery
CORRECT ANSWER
Answer: A. Superior Vena Cava
1
, Explanation: The CVP catheter tip should not be allowed to migrate into the heart
chambers to avoid arrhythmias and perforation.
Question 3
The rapid shallow breathing index (RSBI) is useful in predicting successful weaning from
mechanical ventilation. Prior to extubation this index should be:
A. Between 300 and 400
B. Between 200 and 300
C. Between 100 and 200
D. Less than 100
CORRECT ANSWER
Answer: D. Less than 100
Explanation: RSBI is frequently used to help predict who can be successfully weaned
from mechanical ventilation. With the patient breathing spontaneously, the ventilatory
rate is divided by the tidal volume (liters). An RSBI of less than 100 can predict successful
extubation.
Question 4
The perception of an ordinarily non-noxious stimulus as pain is referred to as:
A. allodynia
B. anesthesia dolorosa
C. dysesthesia
D. hyperalgesia
CORRECT ANSWER
2
, Answer: A. Allodynia
Explanation: Allodynia is the perception of non-noxious stimuli as pain. Dysesthesia is an
unpleasant sensation without a stimulus. Hyperesthesia is an increased response to a
mild stimulus. Anesthesia dolorosa is pain in an area that lacks sensation.
Question 5
Pathophysiologic factors affecting the anesthetic management of patients with
hypothyroidism include:
A. Hypernatremia
B. Hyperglycemia
C. Difficulty with intubation and airway management
D. Increased blood viscosity due to elevated hematocrit
CORRECT ANSWER
Answer: C. Difficulty with intubation and airway management
Explanation: Potential problems of hypothyroidism include hypoglycemia, anemia,
hyponatremia and difficulty during intubation because of a large tongue or the presence
of a goiter. Hypothermia secondary to a low metabolic rate is a common postoperative
complication.
Question 6
Airway obstruction caused by the tongue falling posteriorly against the wall of the pharynx
is secondary to relaxation of the:
A. genioglossus muscle
B. longitudinal muscle of the tongue
3
