Physiological Changes |
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, What are stochastic Theories? They explain aging as events that occur randomly and accumulate over time.
What are non-stochastic theories? It views aging as certain predetermined and timed phenomena.
It is genetically programmed.
What is error theory? - Result of errors in DNA and RNA synthesis
- Accumulation of errors over time.
- Change of cellular activity and function
What is free radical theory? - Free radicals are products of fundamental metabolic activities within the body
(i.e., protein, fats, carbohydrates).
- Normally free radicals are neutralized
- Unstable free radicals impact on cell and organ functions and change
chromosome
- Anti-oxidant (A,C, or E) may reduce the aging effects of free radicals.
What is the wear and tear theory? - Cells wear out over time because of continuous use or injury of body over
time.
- Organs and tissues will function less efficiently with prolonged use.
- Harmful stress factors can exacerbate the wearing-out process
What is programmed theory? This is a non-stochastic theory
- aging is a result of an inner "biological clock" for each cell. When the
presetting clock is released, the cell dies.
What is the auto-immune theory? A non-stochastic theory
-Overtime B- and T-cells changed their role and destroy the cellular regulation
- Elderly are susceptible to infections, cancer, autoimmune disease.
What happens to the number of cells in the body as a it is gradually reduced.
person ages?
What happens to the total body fat as a proportion of It increases
the body's composition?
What happens to lean body mass? It is reduced
Up to when do fat tissue increase? Until the age 60
What happens to cellular solids and bone mass? They are decreased
What happens to extracellular fluids? They remain fairly constant
What happens to intracellular fluid? It is decreased