NR566 (2026-2027) MIDTERM EXAM
REVIEW /LATEST ADVANCED
PHARMACOLOGY FOR CARE OF
FAMILY|AGRADE | A+ GRADED | 100 %
GUARANTEED PASS
QUESTION
Which non-amphetamines are FDA approved for weight loss that have lower abuse risk?
A) Phentermine and Diethylpropion
B) Orlistat and Lorcaserin
C) Naltrexone and Bupropion
D) Liraglutide and Semaglutide
Correct Answer: A
Rationale: Phentermine and Diethylpropion are non-amphetamine FDA-approved weight
loss medications with lower abuse risk compared to amphetamines.
QUESTION
How do Phentermine and Diethylpropion promote weight loss?
A) They are CNS stimulants that suppress appetite by increasing norepinephrine
availability at brain receptors
B) They inhibit lipase in the GI tract
C) They increase satiety by slowing gastric emptying
D) They block opioid receptors
Correct Answer: A
Rationale: Phentermine and Diethylpropion promote weight loss by decreasing appetite.
They are CNS stimulants that suppress appetite by increasing the availability of
norepinephrine at receptors in the brain.
QUESTION
What is the maximum recommended duration of use for non-amphetamines?
A) 3 months or less
B) 6 months or less
,C) 12 months or less
D) 1 month or less
Correct Answer: A
Rationale: The maximum recommended duration of use for non-amphetamines is 3
months or less.
QUESTION
What drug schedule are Phentermine and Diethylpropion under?
A) Schedule IV
B) Schedule II
C) Schedule III
D) Schedule V
Correct Answer: A
Rationale: Phentermine and Diethylpropion are Schedule IV controlled substances.
QUESTION
What labs should be monitored with Phentermine and Diethylpropion?
A) Baseline CMP (watch electrolytes and creatinine) and screen for depression
B) Baseline CBC and screen for anxiety
C) Baseline LFTs and screen for psychosis
D) Baseline TSH and screen for bipolar disorder
Correct Answer: A
Rationale: Baseline CMP should be monitored with Phentermine and Diethylpropion,
watching electrolytes and creatinine, and patients should be screened for depression.
QUESTION
What are the adverse effects of Phentermine?
A) Increased HR and BP, dry mouth, and constipation
B) Decreased HR and BP, diarrhea, and salivation
C) Increased HR and BP, diarrhea, and salivation
D) Decreased HR and BP, dry mouth, and constipation
Correct Answer: A
Rationale: Phentermine adverse effects include increased heart rate and blood pressure,
dry mouth, and constipation.
QUESTION
What is the role of topiramate in weight loss?
A) Increases satiety
B) Decreases satiety
C) Increases appetite
,D) Decreases metabolism
Correct Answer: A
Rationale: Topiramate increases satiety, contributing to weight loss when combined with
phentermine.
QUESTION
What are some Phentermine/topiramate contraindications for use?
A) Not approved in children and contraindicated with severe hepatic impairment
B) Not approved in adults and contraindicated with mild hepatic impairment
C) Approved in children and contraindicated with renal impairment
D) Approved in adults and contraindicated with cardiac impairment
Correct Answer: A
Rationale: Phentermine/topiramate is not approved in children and is contraindicated with
severe hepatic impairment.
QUESTION
How should we educate patients to take Phentermine/topiramate to avoid insomnia?
A) Given before 1600
B) Given after 1600
C) Given at bedtime
D) Given in the morning and at bedtime
Correct Answer: A
Rationale: Phentermine/topiramate should be given before 1600 (4 PM) to avoid insomnia.
QUESTION
What are some high-risk patient conditions that we should use Phentermine/topiramate
with caution?
A) History of drug abuse, glaucoma, pregnancy, HTN, hyperthyroidism
B) History of drug abuse, glaucoma, pregnancy, hypotension, hypothyroidism
C) No history of drug abuse, glaucoma, pregnancy, HTN, hypothyroidism
D) History of drug abuse, cataracts, pregnancy, HTN, hyperthyroidism
Correct Answer: A
Rationale: Phentermine/topiramate should be used with caution in patients with a history
of drug abuse, glaucoma, pregnancy, hypertension, and hyperthyroidism.
QUESTION
What are the adverse effects of Phentermine/topiramate?
A) Insomnia, nervousness, anxiety, depression, blurred vision
B) Drowsiness, calmness, euphoria, clear vision
C) Insomnia, calmness, euphoria, blurred vision
, D) Drowsiness, nervousness, anxiety, clear vision
Correct Answer: A
Rationale: Phentermine/topiramate adverse effects include insomnia, nervousness,
anxiety, depression, and blurred vision.
QUESTION
Which of the following would be a contraindication to prescribing
phentermine/topiramate?
A) Glaucoma, hypertension, and hyperthyroidism
B) Hypothyroidism and vitamin D deficiency
C) Glaucoma and hypothyroidism
D) Hypertension and vitamin D deficiency
Correct Answer: A
Rationale: Contraindications to prescribing phentermine/topiramate include glaucoma,
hypertension, and hyperthyroidism.
QUESTION
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat by
30%.
A) GI tract
B) Liver
C) Kidneys
D) Lungs
Correct Answer: A
Rationale: Orlistat is a lipase inhibitor that acts on the GI tract and reduces absorption of
fat by 30%.
QUESTION
Take multivitamin ___ hours before/after to supplement fat-soluble vitamins that may not
be absorbed well when taking Orlistat.
A) 2
B) 4
C) 6
D) 8
Correct Answer: A
Rationale: Take multivitamins 2 hours before or after Orlistat to supplement fat-soluble
vitamins that may not be absorbed well.
QUESTION
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____.
REVIEW /LATEST ADVANCED
PHARMACOLOGY FOR CARE OF
FAMILY|AGRADE | A+ GRADED | 100 %
GUARANTEED PASS
QUESTION
Which non-amphetamines are FDA approved for weight loss that have lower abuse risk?
A) Phentermine and Diethylpropion
B) Orlistat and Lorcaserin
C) Naltrexone and Bupropion
D) Liraglutide and Semaglutide
Correct Answer: A
Rationale: Phentermine and Diethylpropion are non-amphetamine FDA-approved weight
loss medications with lower abuse risk compared to amphetamines.
QUESTION
How do Phentermine and Diethylpropion promote weight loss?
A) They are CNS stimulants that suppress appetite by increasing norepinephrine
availability at brain receptors
B) They inhibit lipase in the GI tract
C) They increase satiety by slowing gastric emptying
D) They block opioid receptors
Correct Answer: A
Rationale: Phentermine and Diethylpropion promote weight loss by decreasing appetite.
They are CNS stimulants that suppress appetite by increasing the availability of
norepinephrine at receptors in the brain.
QUESTION
What is the maximum recommended duration of use for non-amphetamines?
A) 3 months or less
B) 6 months or less
,C) 12 months or less
D) 1 month or less
Correct Answer: A
Rationale: The maximum recommended duration of use for non-amphetamines is 3
months or less.
QUESTION
What drug schedule are Phentermine and Diethylpropion under?
A) Schedule IV
B) Schedule II
C) Schedule III
D) Schedule V
Correct Answer: A
Rationale: Phentermine and Diethylpropion are Schedule IV controlled substances.
QUESTION
What labs should be monitored with Phentermine and Diethylpropion?
A) Baseline CMP (watch electrolytes and creatinine) and screen for depression
B) Baseline CBC and screen for anxiety
C) Baseline LFTs and screen for psychosis
D) Baseline TSH and screen for bipolar disorder
Correct Answer: A
Rationale: Baseline CMP should be monitored with Phentermine and Diethylpropion,
watching electrolytes and creatinine, and patients should be screened for depression.
QUESTION
What are the adverse effects of Phentermine?
A) Increased HR and BP, dry mouth, and constipation
B) Decreased HR and BP, diarrhea, and salivation
C) Increased HR and BP, diarrhea, and salivation
D) Decreased HR and BP, dry mouth, and constipation
Correct Answer: A
Rationale: Phentermine adverse effects include increased heart rate and blood pressure,
dry mouth, and constipation.
QUESTION
What is the role of topiramate in weight loss?
A) Increases satiety
B) Decreases satiety
C) Increases appetite
,D) Decreases metabolism
Correct Answer: A
Rationale: Topiramate increases satiety, contributing to weight loss when combined with
phentermine.
QUESTION
What are some Phentermine/topiramate contraindications for use?
A) Not approved in children and contraindicated with severe hepatic impairment
B) Not approved in adults and contraindicated with mild hepatic impairment
C) Approved in children and contraindicated with renal impairment
D) Approved in adults and contraindicated with cardiac impairment
Correct Answer: A
Rationale: Phentermine/topiramate is not approved in children and is contraindicated with
severe hepatic impairment.
QUESTION
How should we educate patients to take Phentermine/topiramate to avoid insomnia?
A) Given before 1600
B) Given after 1600
C) Given at bedtime
D) Given in the morning and at bedtime
Correct Answer: A
Rationale: Phentermine/topiramate should be given before 1600 (4 PM) to avoid insomnia.
QUESTION
What are some high-risk patient conditions that we should use Phentermine/topiramate
with caution?
A) History of drug abuse, glaucoma, pregnancy, HTN, hyperthyroidism
B) History of drug abuse, glaucoma, pregnancy, hypotension, hypothyroidism
C) No history of drug abuse, glaucoma, pregnancy, HTN, hypothyroidism
D) History of drug abuse, cataracts, pregnancy, HTN, hyperthyroidism
Correct Answer: A
Rationale: Phentermine/topiramate should be used with caution in patients with a history
of drug abuse, glaucoma, pregnancy, hypertension, and hyperthyroidism.
QUESTION
What are the adverse effects of Phentermine/topiramate?
A) Insomnia, nervousness, anxiety, depression, blurred vision
B) Drowsiness, calmness, euphoria, clear vision
C) Insomnia, calmness, euphoria, blurred vision
, D) Drowsiness, nervousness, anxiety, clear vision
Correct Answer: A
Rationale: Phentermine/topiramate adverse effects include insomnia, nervousness,
anxiety, depression, and blurred vision.
QUESTION
Which of the following would be a contraindication to prescribing
phentermine/topiramate?
A) Glaucoma, hypertension, and hyperthyroidism
B) Hypothyroidism and vitamin D deficiency
C) Glaucoma and hypothyroidism
D) Hypertension and vitamin D deficiency
Correct Answer: A
Rationale: Contraindications to prescribing phentermine/topiramate include glaucoma,
hypertension, and hyperthyroidism.
QUESTION
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat by
30%.
A) GI tract
B) Liver
C) Kidneys
D) Lungs
Correct Answer: A
Rationale: Orlistat is a lipase inhibitor that acts on the GI tract and reduces absorption of
fat by 30%.
QUESTION
Take multivitamin ___ hours before/after to supplement fat-soluble vitamins that may not
be absorbed well when taking Orlistat.
A) 2
B) 4
C) 6
D) 8
Correct Answer: A
Rationale: Take multivitamins 2 hours before or after Orlistat to supplement fat-soluble
vitamins that may not be absorbed well.
QUESTION
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____.