!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
NAPLEX PREP QUESTIONS
Name three examples of at-home tests that can be purchased OTC? - ANS-pregnancy,
ovulation, HIV, herpes, fecal occult blood, drug tests
lifespan of platelets? - ANS-7-10 days -- reason you have to hold aspirin 10 days prior
to surgery
When would a CMP be helpful? - ANS-getting baseline electrolyte labs and liver
function tests in one blood draw
These are the three white blood cells (leukocytes) classified further as granulocytes -
ANS-neutrophils, basophils, eosinophils
Drug-induced agranulocytosis caused by what drugs? - ANS-clozapine, propylthiouracil,
methimazole, procainamide, carbamazepine, bactrim, isoniazid
For what lab values does JCO require a specific institution protocol? - ANS-critical lab
values and in that protocol, physicians are required to have a time frame to manage
them
Define "myelosuppression" - ANS-a reduction in all hematopoietic cells (RBCs,
platelets, leukocytes)
What medications increase serum calcium ? - ANS-vitamin D, thiazides
What medications DECREASE serum calcium? - ANS-corticosteroids, long-term
heparin, loops, bisphosphonates, cinacalcet, topiramate, calcitonin
T/F You must correct calcium every time you get a value for serum calcium. -
ANS-False, ionized calcium does not need to be corrected.
Corrected Ca = Reported Ca + [(4-albumin) x 0.8]
What medications / disease states lower serum magnesium?
normal 1.3-2.1 mEq/L - ANS-PPIs, diuretics, amphoB, echinocandins
Diarrhea, chronic alcohol use disorder
!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
,!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
What medications elevate serum magnesium?
normal 1.3-2.1 mEq/L - ANS-Mg-containing antacids, laxatives in renal impairment
Phosphate levels (normal 2.3-4.7 mg/L) in the blood can be lowered by... -
ANS-phosphate binders, oral Calcium
Role of PO4 in the body... - ANS-in bone metabolism, helps to buffer acid-base balance
Electrolyte imbalances/ changes resulting from renal impairment are: - ANS-increased
phosphate
increased BUN
increased Scr
Main intracellular cation that's normal range is 3.5-5mEq/L? - ANS-potassium
Elevate or reduce serum concentrations of potassium?
A. Corticosteroids
B. ACEi/ARBs/aliskerin
C. Canagliflozin
D. Albuterol
E. Loops
F. Insulin
G. Bactrim
H. Immunosuppressives (cyclosporine/ tacrolimus) - ANS-A. lower
B. elevate
C. elevate
D. lower
E. lower
F. lower
G. elevate
H. elevate
Medications that reduce extracellular sodium concentrations (normal 135-145mEq/L) -
ANS-carbamazepine, oxcarbazepine, SSRIs, diuretics
How does a salicylate overdose affect the body's acid-base balance? - ANS-body
enters alkalosis
When the anion gap is elevated above 5-12 normal range, what is the body's metabolic
state? - ANS-metabolic acidosis
!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
,!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
A 4 year old gets a new prescription for an antibiotic and her mother is asking you if it's
appropriately dosed. What references could you refer to check? - ANS-Harriet Lane
Handbook
Red Book by AAP
You get a call from a Dr. about to discharge a patient from the hospital who just had a GI
ulcer bleed. The doctor is asking what formulations are available for this patient's
maintenance medications because he is afraid oral tablets will be too harsh. What
references do you check? - ANS-Package inserts
Any drug monograph - Lexi, Micromedex, ClinPharm, Facts and Comparisons
A very concerned father rushes into your pharmacy after finding a small white pill on his
daughter's bedroom floor. He asks you to identify the medication. How would you go
about doing this if you didn't recognize the tablet? - ANS-Use the Drug ID tool on
Micromedex, Lexicomp, Pillbox, Ident-A-Drug
**only source without pill ID = AHFS
Which of the following are included in the package insert?
A. Indications
B. Black box warnings
C. Drug cost
D. Major changes in safety
E. Dosing administration
F. Drug strengths and formulations
G. ADRs and DDIs
H. Mechanism of Action
I. Contraindications
J. Specific trial results from clinical trials - ANS-All of the above EXCEPT C.
Drug cost and off-label indications not on package insert --it is an FDA-approved item
part of the drug labeling. only FDA-approved indications included
There are four locations to find the package insert. List 2 - ANS-Daily Med
Drugs@FDA
manufacturer website
attached to box/printed
!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
,!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
Which resource would you go to first if doing an in-depth research paper on off-label
indications of duloxetine? - ANS-American Hospital Formulary Service (AHFS)
- can find on Lexicomp
- no pill ID, no pricing, no natural products
There are many free resources that can be accessed. These are: - ANS-Drug info portal
(National Library of Medicine - includes DailyMed, LactMed, Pillbox)
Epocrates (Plus offers ICD codes for billing at a fee)
Prescriber's Digital reference (drugs, vaccines, biologics)
Drugs.com
RxList
You are working in the pharmacy basement when a doctor calls and asks roughly how
much a medication will cost for a patient as she wants to make sure the patient can
afford it before prescribing. What two resources offer drug pricing? - ANS-Redbook
(Micromedex)
Medi-Span Price Rx
You are volunteering at a refugee community center in your city to do a brown bag event
with individuals. A lot of the medications being taken are from Venezuela, Peru,
Colombia and your Spanish is not helping you out today. How can you be sure which
medications patients are taking? - ANS-International drug names compendia
Index Nominum
Martindale's
USAN (USP Dictionary)
Lexicomp
When marketing a new OTC product, a manufacturer has two possible pathways to go
through for approval. - ANS-1. NDA - through FDA CDER and this will then be an
FDA-approved drug
2. OTC monograph process - labeling can be on the container itself (ie. vitamins)
Match the organization to the population/ disease state guidelines
!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
NAPLEX PREP QUESTIONS
Name three examples of at-home tests that can be purchased OTC? - ANS-pregnancy,
ovulation, HIV, herpes, fecal occult blood, drug tests
lifespan of platelets? - ANS-7-10 days -- reason you have to hold aspirin 10 days prior
to surgery
When would a CMP be helpful? - ANS-getting baseline electrolyte labs and liver
function tests in one blood draw
These are the three white blood cells (leukocytes) classified further as granulocytes -
ANS-neutrophils, basophils, eosinophils
Drug-induced agranulocytosis caused by what drugs? - ANS-clozapine, propylthiouracil,
methimazole, procainamide, carbamazepine, bactrim, isoniazid
For what lab values does JCO require a specific institution protocol? - ANS-critical lab
values and in that protocol, physicians are required to have a time frame to manage
them
Define "myelosuppression" - ANS-a reduction in all hematopoietic cells (RBCs,
platelets, leukocytes)
What medications increase serum calcium ? - ANS-vitamin D, thiazides
What medications DECREASE serum calcium? - ANS-corticosteroids, long-term
heparin, loops, bisphosphonates, cinacalcet, topiramate, calcitonin
T/F You must correct calcium every time you get a value for serum calcium. -
ANS-False, ionized calcium does not need to be corrected.
Corrected Ca = Reported Ca + [(4-albumin) x 0.8]
What medications / disease states lower serum magnesium?
normal 1.3-2.1 mEq/L - ANS-PPIs, diuretics, amphoB, echinocandins
Diarrhea, chronic alcohol use disorder
!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
,!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
What medications elevate serum magnesium?
normal 1.3-2.1 mEq/L - ANS-Mg-containing antacids, laxatives in renal impairment
Phosphate levels (normal 2.3-4.7 mg/L) in the blood can be lowered by... -
ANS-phosphate binders, oral Calcium
Role of PO4 in the body... - ANS-in bone metabolism, helps to buffer acid-base balance
Electrolyte imbalances/ changes resulting from renal impairment are: - ANS-increased
phosphate
increased BUN
increased Scr
Main intracellular cation that's normal range is 3.5-5mEq/L? - ANS-potassium
Elevate or reduce serum concentrations of potassium?
A. Corticosteroids
B. ACEi/ARBs/aliskerin
C. Canagliflozin
D. Albuterol
E. Loops
F. Insulin
G. Bactrim
H. Immunosuppressives (cyclosporine/ tacrolimus) - ANS-A. lower
B. elevate
C. elevate
D. lower
E. lower
F. lower
G. elevate
H. elevate
Medications that reduce extracellular sodium concentrations (normal 135-145mEq/L) -
ANS-carbamazepine, oxcarbazepine, SSRIs, diuretics
How does a salicylate overdose affect the body's acid-base balance? - ANS-body
enters alkalosis
When the anion gap is elevated above 5-12 normal range, what is the body's metabolic
state? - ANS-metabolic acidosis
!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
,!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
A 4 year old gets a new prescription for an antibiotic and her mother is asking you if it's
appropriately dosed. What references could you refer to check? - ANS-Harriet Lane
Handbook
Red Book by AAP
You get a call from a Dr. about to discharge a patient from the hospital who just had a GI
ulcer bleed. The doctor is asking what formulations are available for this patient's
maintenance medications because he is afraid oral tablets will be too harsh. What
references do you check? - ANS-Package inserts
Any drug monograph - Lexi, Micromedex, ClinPharm, Facts and Comparisons
A very concerned father rushes into your pharmacy after finding a small white pill on his
daughter's bedroom floor. He asks you to identify the medication. How would you go
about doing this if you didn't recognize the tablet? - ANS-Use the Drug ID tool on
Micromedex, Lexicomp, Pillbox, Ident-A-Drug
**only source without pill ID = AHFS
Which of the following are included in the package insert?
A. Indications
B. Black box warnings
C. Drug cost
D. Major changes in safety
E. Dosing administration
F. Drug strengths and formulations
G. ADRs and DDIs
H. Mechanism of Action
I. Contraindications
J. Specific trial results from clinical trials - ANS-All of the above EXCEPT C.
Drug cost and off-label indications not on package insert --it is an FDA-approved item
part of the drug labeling. only FDA-approved indications included
There are four locations to find the package insert. List 2 - ANS-Daily Med
Drugs@FDA
manufacturer website
attached to box/printed
!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
,!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
Which resource would you go to first if doing an in-depth research paper on off-label
indications of duloxetine? - ANS-American Hospital Formulary Service (AHFS)
- can find on Lexicomp
- no pill ID, no pricing, no natural products
There are many free resources that can be accessed. These are: - ANS-Drug info portal
(National Library of Medicine - includes DailyMed, LactMed, Pillbox)
Epocrates (Plus offers ICD codes for billing at a fee)
Prescriber's Digital reference (drugs, vaccines, biologics)
Drugs.com
RxList
You are working in the pharmacy basement when a doctor calls and asks roughly how
much a medication will cost for a patient as she wants to make sure the patient can
afford it before prescribing. What two resources offer drug pricing? - ANS-Redbook
(Micromedex)
Medi-Span Price Rx
You are volunteering at a refugee community center in your city to do a brown bag event
with individuals. A lot of the medications being taken are from Venezuela, Peru,
Colombia and your Spanish is not helping you out today. How can you be sure which
medications patients are taking? - ANS-International drug names compendia
Index Nominum
Martindale's
USAN (USP Dictionary)
Lexicomp
When marketing a new OTC product, a manufacturer has two possible pathways to go
through for approval. - ANS-1. NDA - through FDA CDER and this will then be an
FDA-approved drug
2. OTC monograph process - labeling can be on the container itself (ie. vitamins)
Match the organization to the population/ disease state guidelines
!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
fNAPLEX NAPLEX
PREP PREPQUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!######################################
QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!#######################NAPLEX
PREP QUESTIONS.pdfNAPLEX PREP QUESTIONS.pdf!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
PREP QU
