BSG COMPREHENSIVE EXAM FULL SOLUTION
STUDY GUIDE
◉ What are major causes of microcytic anemia?
Answer: TAILS
Thalessemia
anemia of chronic disease (asd)
iron deficiency anemia
lead poisoning
sideroblastic anemia
◉ Which above are the most common microcytic anemia?
Answer: Iron deficiency anemia
◉ Who in IDA are most common in?
Answer: Pregnant women
women of childbearing ages
elderly
◉ What is iron required for?
,Answer: Hemoglobin synthesis
Oxygen transport
Normal erythropoiesis
◉ Causes of ida?
Answer: Decrease iron intake
vegan
Celiac disease
Crohn disease
Gastric bypass
Gastrectomy
Duodenal/jejunal surgery
Rapid GI motility
H2 blockers (cimetidine)
◉ Common causes of chronic blood loss in adults?
Answer: GI
Peptic ulcer
Gastritis
Colon cancer
Diverticulosis
Hemorrhoids
,Ulcerative colitis
Crohn disease
GU
Menorrhagia
Hematuria
Bladder cancer
◉ Patho of IDA?
Answer: ↓ Heme synthesis
→ ↓ Hemoglobin
→ Smaller RBCs
→ Hypochromic microcytic anemia
◉ Causes of anemia of chronic disease?
Answer: Rheumatoid arthritis
Chronic infection
Cancer
Chronic inflammatory diseases
◉ What is HSV?
Answer: Herpes simplex virus that affects mouth, genitals,
, ◉ How does HSV remain lifelong?
Answer: Due to viral latency in sensory ganglia
◉ how is HSV transmitted?
Answer: direct contact wiht active lesions, saliva, semen, cervical
secretions
· Oral-genital sexual contact
· Asymptomatic viral shedding (major source)
◉ what is incubation period for HSV?
Answer: 2-21 days
◉ pathophysiology of hsv?
Answer: 1. Virus enters skin/mucosa.
2. Replicates in keratinocytes.
3. Travels via sensory nerves.
4. Establishes latency in sensory ganglia.
◉ reactivation triggers of hsv?
Answer: · Stress
· Fever
STUDY GUIDE
◉ What are major causes of microcytic anemia?
Answer: TAILS
Thalessemia
anemia of chronic disease (asd)
iron deficiency anemia
lead poisoning
sideroblastic anemia
◉ Which above are the most common microcytic anemia?
Answer: Iron deficiency anemia
◉ Who in IDA are most common in?
Answer: Pregnant women
women of childbearing ages
elderly
◉ What is iron required for?
,Answer: Hemoglobin synthesis
Oxygen transport
Normal erythropoiesis
◉ Causes of ida?
Answer: Decrease iron intake
vegan
Celiac disease
Crohn disease
Gastric bypass
Gastrectomy
Duodenal/jejunal surgery
Rapid GI motility
H2 blockers (cimetidine)
◉ Common causes of chronic blood loss in adults?
Answer: GI
Peptic ulcer
Gastritis
Colon cancer
Diverticulosis
Hemorrhoids
,Ulcerative colitis
Crohn disease
GU
Menorrhagia
Hematuria
Bladder cancer
◉ Patho of IDA?
Answer: ↓ Heme synthesis
→ ↓ Hemoglobin
→ Smaller RBCs
→ Hypochromic microcytic anemia
◉ Causes of anemia of chronic disease?
Answer: Rheumatoid arthritis
Chronic infection
Cancer
Chronic inflammatory diseases
◉ What is HSV?
Answer: Herpes simplex virus that affects mouth, genitals,
, ◉ How does HSV remain lifelong?
Answer: Due to viral latency in sensory ganglia
◉ how is HSV transmitted?
Answer: direct contact wiht active lesions, saliva, semen, cervical
secretions
· Oral-genital sexual contact
· Asymptomatic viral shedding (major source)
◉ what is incubation period for HSV?
Answer: 2-21 days
◉ pathophysiology of hsv?
Answer: 1. Virus enters skin/mucosa.
2. Replicates in keratinocytes.
3. Travels via sensory nerves.
4. Establishes latency in sensory ganglia.
◉ reactivation triggers of hsv?
Answer: · Stress
· Fever
