Test Bank For Clayton’s Basic Pharmacology for Nurses{19th Edition} By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton| All Chapters (1-48) Covered | Correct Answers with Rationals | Updated

TestBankForClayton’sBasicPharmacologyforNurses19th
Edition
ByMichelleJ.Willihnganz,SamuelL.Gurevitz,BruceClayton
Complete

,Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz: Clayton
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’s Basic Pharmacology for Nurses, 19th Edition
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MULTIPLE CHOICE rt




1. Whichname identifiesa druglisted bythe US Food and D
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rug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C rt


The official name is the name under which a drug is listed by th
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e FDA. The brand name, or trademark, is the name given t o a
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drug by its manufacturer. The nonproprietary, or generic, nam
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e is provided by the United States Adopted Names Coun cil.
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DIF: Cognitive Level: Knowledge REF: p. 9 rt rt rt rt


OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care Environmen
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t TOP: Nursing Process Step: Assessment
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CON:
Patient Education rt




2. Whichsource contains information specific to nutritional supplements?
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a. USPDictionary of USAN &International Drug Names rt rt rt rt rt


b. Natural Medicines Comprehensive Database rt rt rt


c. United States Pharmacopoeia/National Formulary(USPNF) rt rt rt


d. DrugInteraction Facts rt rt




ANS: C rt


United States Pharmacopoeia/National Formulary contains information specific to nutritional s u
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pplements. USP Dictionary of USAN & International Drug Names is a compilation of drug na mes
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, pronunciation guide, and possible future FDA approved drugs; it does not include nutritio nal su
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pplements. Natural Medicines Comprehensive Database contains rt rt rt rt rt


evidence-
based information on herbal medicines and herbal combination products; it does not include inf or
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mation specific to nutritional supplements. Drug Interaction Facts contains comprehensive i nfor
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mation on drug interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 rt rt rt rt


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integ
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rity
TOP: NursingProcess Step: Assessment
r t rt rt rt CON: Nutrition |Patient Education rt rt rt




3. Whichdrugreference contains drugmonographs that describe all drugs in a therapeutic class?
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a. Drug Facts and Comparisons rt rt rt

,Test Bank ForvClayton’s Basic PharmacologyvforvNurses 19th Edition
rt rt rt rt rt rt 3

b. DrugInteraction Facts rt rt


c. Handbook on Injectable Drugs rt rt rt


d. Martindale—The Complete Drug Reference rt rt rt




ANS: A rt


Drug Facts and Comparisons contains drug monographs that describe all drugs in a th er
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apeutic class. Monographs are formatted as tables to allow comparison of similar pro duct
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s, brand names, manufacturers, cost indices, and available dosage forms Online ve rsion is
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available.
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DIF: Cognitive Level: Knowledge REF: p. 4vTable 1.2 rt rt rt rt rt


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
rtrt rt rt rt rt rt rt


TOP: NursingProcess Step: Assessment
r t CON: Safety|Patient Education |Clinical Judgment rt rt rt rt rt tr rt rt rt




4. Whichdrugreference contains monographs about virtuallyeverysingle-
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entitydrug available in the United States and describes therapeutic uses of drugs, including ap prov
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ed and unapproved uses?
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a. Martindale: The Complete Drug Reference rt rt rt rt


b. AHFSDrug Information rt rt


c. DrugReference tr


d. DrugFacts and Comparisons rt rt rt




ANS: B rt


AHFS Drug Information contains monographs about virtually every single-
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entitydrug available inthe United States and describes therapeuticuses ofdrugs, includingappr ove
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d and unapproved uses.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 rt rt rt rt rt rt


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
rtrt rt rt rt rt rt rt


TOP: NursingProcess Step: Planning
r t CON: Safety|Patient Education |Clinical Judgment rt rt rt rt rt tr rt rt rt




5. Which online drug reference makes available to healthcare providers and the public a stand ard
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, comprehensive, up-to-date look up and downloadable resource about medicines?
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a. American Drug Index rt rt


b. American Hospital Formulary rt rt


c. DailyMed
d. DrugReference rt




ANS: C rt


DailyMed makes available to healthcare providers and the public a standard, comprehensive, u
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p-to-
date look up and downloadable resource about medicines. The American Drug Index is not app ro
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priate for patient use. The American Hospital Formulary is not appropriate for patient use. Th
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e drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 rt rt r t rt rt rt rt


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integ
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rity
TOP: Nursing Process Step: Implementation
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CON: Safety |Patient Education |Clinical Judgment
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6. Whichlegislation authorizes the FDAto determine the safetyofadrugbefore its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938) rt rt rt rt rt rt


b. DurhamHumphreyAmendment (1952) rt tr rt

, Test Bank ForvClayton’s Basic PharmacologyvforvNurses 19th Edition
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c. Controlled Substances Act (1970) rt rt rt


d. Kefauver Harris Drug Amendment (1962) rt rt rt rt




ANS: A rt


The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safet y o
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f all drugs before marketing. Later amendments and acts helped tighten FDA control and en surev
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drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used saf
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ely without medical supervision and restricts their sale to prescription by a licensed pr actitioner.
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The Controlled Substances Act addresses onlycontrolled substances and their catego rization. The
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Kefauver Harris Drug Amendment ensures drug efficacy and greater drug safety. Drug manufact
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urers are required to prove to the FDA the effectiveness of their products before marketing them.
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DIF: Cognitive Level: Knowledge rt rt


REF: p. 5Table l.3 OBJ: 5 rt rt tr rt rt r t


NAT: NCLEX Client Needs Category: Physiological Integrity rt rt rt rt rt rt rt


TOP: Nursing Process Step: Assessment
r t rt rt rt


CON: Safety |Patient Education |Evidence |Health Care Law
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7. Which classification does meperidine (Demerol) fall under?
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a. I
b. II
c. III
d. IV
ANS: B rt


Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to se vere
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psychological and physical dependence. Schedule I drugs have high potential for abuse and no rec
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ognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low to m
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oderate physical dependence or high psychological dependence. Schedule IV drugs ha ve low pot
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ential for abuse. Use may lead to limited physical or psychological dependence.
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DIF: Cognitive Level: Knowledge
r t r t REF: p. 10 rt rt rt rt


OBJ: 2 NAT: NCLEX Client Needs Category: Safe, Effective Car e rt rt rt rt rt rt rt rt rt rt rt


Environment
TOP: NursingProcess Step: Assessment
r t CON: Patient Education |Addiction |Pain rt rt rt r t r t rt rt rt rt tr




8. Whichaction would theFDAtaketo expedite drug development and approval foran outbreak o f sm
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allpox?
a. List smallpox as a health orphan disease. rt rt rt rt rt rt


b. Omit the preclinical research phase. rt rt rt rt


c. Extend the clinical research phase. rt rt rt rt


d. Fast track the investigational drug. rt rt rt rt




ANS: D rt


Once the Investigational New Drug Application has been approved, the drug can receive high es
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t priority within the agency, which is called fast tracking. A smallpox outbreak would beco me a
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priority concern in the world. Orphan diseases are not researched in a priority manner. Pr eclinica
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l research is not omitted. Extending any phase of the research would mean a longer tim e to develop
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a vaccine. The FDA must ensure that all phases of the preclinical and clinical resea rch phase have
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been completed in a safe manner.
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DIF: r t Cognitive Level: Knowledge rt rt REF: p. 7 r t rt OBJ: 5 rt