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NRS 455 Exam 3 V1 | NRS 455 Pathophysiology | Actual Q&A with Rationale (NRS455 Exam 3) | Grand Canyon University

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NRS 455 Exam 3 V1 | NRS 455 Pathophysiology | Actual Q&A with Rationale (NRS455 Exam 3) | Grand Canyon University

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NRS 455 Exam 3 V1 | NRS 455 Pathophysiology |
Actual Q&A with Rationale (NRS455 Exam 3) |
Grand Canyon University
1. A patient is admitted with a suspected diagnosis of Type 1 Diabetes Mellitus. Which of the

following clinical manifestations should the nurse expect to find? (Select all that apply)

A. Polyuria


B. Polydipsia


C. Weight gain


D. Polyphagia


E. Fatigue


F. Increased energy levels


Correct Answer: A, B, D, E


Explanation: Type 1 Diabetes Mellitus is characterized by the ‘three Ps’: polyuria,

polydipsia, and polyphagia. The lack of insulin prevents glucose from entering cells, leading

to cellular starvation and subsequent weight loss despite increased intake. Fatigue is a

common secondary symptom due to the metabolic shift toward using fats and proteins for

energy instead of glucose.


2. Which pathophysiological process occurs in a patient experiencing Graves’ disease?

A. Production of thyroid-stimulating immunoglobulins (TSI) that mimic TSH

,B. Destruction of the thyroid gland by T-cells


C. Insufficient secretion of Thyrotropin-releasing hormone from the hypothalamus


D. Iodine deficiency leading to goiter formation


Correct Answer: A


Explanation: Graves’ disease is an autoimmune disorder where the body produces

antibodies known as thyroid-stimulating immunoglobulins. These antibodies bind to the

TSH receptors on the thyroid gland and stimulate the overproduction of thyroxine. This

leads to the characteristic symptoms of hyperthyroidism, such as tachycardia, heat

intolerance, and exophthalmos.


3. A patient presents with a ‘buffalo hump,’ moon face, and purple striae on the abdomen.

Which laboratory finding would the nurse most likely anticipate?

A. Hypercortisolism


B. Hyperkalemia


C. Hypoglycemia


D. Hypocalcemia


Correct Answer: A


Explanation: The clinical signs described are classic presentations of Cushing’s Syndrome,

which results from excessive levels of cortisol. Cortisol influences metabolism and fat

distribution, leading to the characteristic fat pads and skin changes. Elevated cortisol levels

, are often confirmed through 24-hour urinary free cortisol tests or late-night salivary

cortisol monitoring.


4. Which of the following are acute complications of Diabetes Mellitus? (Select all that apply)

A. Diabetic Ketoacidosis (DKA)


B. Hyperosmolar Hyperglycemic Nonketotic Syndrome (HHNS)


C. Hypoglycemia


D. Diabetic Retinopathy


E. Diabetic Nephropathy


Correct Answer: A, B, C


Explanation: Acute complications of diabetes are life-threatening conditions that occur

rapidly, including DKA, HHNS, and hypoglycemia. Retinopathy and nephropathy are

considered chronic microvascular complications that develop over many years of poor

glycemic control. DKA is more common in Type 1 patients, while HHNS is typically seen in

elderly Type 2 patients.


5. A patient with Addison’s disease is at risk for an Addisonian crisis. Which trigger is most

likely to cause this life-threatening event?

A. Sudden cessation of long-term corticosteroid therapy


B. Excessive intake of sodium


C. Exposure to cold weather

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