BMTCN UPDATED EXAM QUESTIONS AND
CORRECT ANSWERS
●● Which portion of the immunoglobulin activates the complement
pathway?
A. MHC Class I
B. Fab
C. Fc
D. MHC Class II
Answer: C. Fc
The Fc region activates the complement pathway.
●● Which of the following is a class II HLA antigen?
A. B
B. DR
C. A
D. C
Answer: B. DR
,HLA DR, DQ and DP are class II antigens.
●● Which of the following is a disadvantage for the host of matched
sibling/related donor stem cells?
A. Delayed time to engraftment
B. Increased rate of infection
C. Limited number of cells available
D. Graft-versus-host disease
Answer: D. Graft-versus-host disease
GVHD is a risk when using a matched sibling/related donor.
●● Which of the following statements by the nurse indicates an
understanding of the teaching regarding hematopoietic stem cells?
A. A high number are normally found in the peripheral circulation
B. They spend the majority of their life in an actively dividing state
C. A percentage of progenitor cells are self-renewing
D. They express protein markers on their cell surface
Answer: D. They express protein markers on their cell surface
, Hematopoietic stem cells express protein markers on their cell surface
that define the type of cell and facilitate communication with other cells.
●● A pre-transplant patient asks about ABO compatibility with the
donor. The nurse explains that:
A. there is less risk of GVHD.
B. the likelihood of engraftment is increased.
C. it is not essential for success.
D. compatibility is associated with better outcomes.
Answer: C. it is not essential for success.
ABO compatibility is not necessary for successful transplant
●● Which of the following factors affect the success of stem cell
mobilization?
A. Vaccination history
B. Exposure to prior radiation
C. Prior pregnancies
D. Ethnic origin
Answer: B. Exposure to prior radiation
CORRECT ANSWERS
●● Which portion of the immunoglobulin activates the complement
pathway?
A. MHC Class I
B. Fab
C. Fc
D. MHC Class II
Answer: C. Fc
The Fc region activates the complement pathway.
●● Which of the following is a class II HLA antigen?
A. B
B. DR
C. A
D. C
Answer: B. DR
,HLA DR, DQ and DP are class II antigens.
●● Which of the following is a disadvantage for the host of matched
sibling/related donor stem cells?
A. Delayed time to engraftment
B. Increased rate of infection
C. Limited number of cells available
D. Graft-versus-host disease
Answer: D. Graft-versus-host disease
GVHD is a risk when using a matched sibling/related donor.
●● Which of the following statements by the nurse indicates an
understanding of the teaching regarding hematopoietic stem cells?
A. A high number are normally found in the peripheral circulation
B. They spend the majority of their life in an actively dividing state
C. A percentage of progenitor cells are self-renewing
D. They express protein markers on their cell surface
Answer: D. They express protein markers on their cell surface
, Hematopoietic stem cells express protein markers on their cell surface
that define the type of cell and facilitate communication with other cells.
●● A pre-transplant patient asks about ABO compatibility with the
donor. The nurse explains that:
A. there is less risk of GVHD.
B. the likelihood of engraftment is increased.
C. it is not essential for success.
D. compatibility is associated with better outcomes.
Answer: C. it is not essential for success.
ABO compatibility is not necessary for successful transplant
●● Which of the following factors affect the success of stem cell
mobilization?
A. Vaccination history
B. Exposure to prior radiation
C. Prior pregnancies
D. Ethnic origin
Answer: B. Exposure to prior radiation
